ID   MARB_ECOLI              Reviewed;          72 AA.
AC   P31121;
DT   01-JUL-1993, integrated into UniProtKB/Swiss-Prot.
DT   01-JUL-1993, sequence version 1.
DT   03-AUG-2022, entry version 112.
DE   RecName: Full=Multiple antibiotic resistance protein MarB;
GN   Name=marB; OrderedLocusNames=b1532, JW1525;
OS   Escherichia coli (strain K12).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=83333;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=8383113; DOI=10.1128/jb.175.5.1484-1492.1993;
RA   Cohen S.P., Haechler H., Levy S.B.;
RT   "Genetic and functional analysis of the multiple antibiotic resistance
RT   (mar) locus in Escherichia coli.";
RL   J. Bacteriol. 175:1484-1492(1993).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=K12;
RX   PubMed=8491710; DOI=10.1128/jb.175.10.2888-2894.1993;
RA   Gambino L., Gracheck S., Miller P.F.;
RT   "Overexpression of the MarA positive regulator is sufficient to confer
RT   multiple antibiotic resistance in Escherichia coli.";
RL   J. Bacteriol. 175:2888-2894(1993).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX   PubMed=9097039; DOI=10.1093/dnares/3.6.363;
RA   Aiba H., Baba T., Fujita K., Hayashi K., Inada T., Isono K., Itoh T.,
RA   Kasai H., Kashimoto K., Kimura S., Kitakawa M., Kitagawa M., Makino K.,
RA   Miki T., Mizobuchi K., Mori H., Mori T., Motomura K., Nakade S.,
RA   Nakamura Y., Nashimoto H., Nishio Y., Oshima T., Saito N., Sampei G.,
RA   Seki Y., Sivasundaram S., Tagami H., Takeda J., Takemoto K., Takeuchi Y.,
RA   Wada C., Yamamoto Y., Horiuchi T.;
RT   "A 570-kb DNA sequence of the Escherichia coli K-12 genome corresponding to
RT   the 28.0-40.1 min region on the linkage map.";
RL   DNA Res. 3:363-377(1996).
RN   [4]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / MG1655 / ATCC 47076;
RX   PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA   Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA   Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA   Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B.,
RA   Shao Y.;
RT   "The complete genome sequence of Escherichia coli K-12.";
RL   Science 277:1453-1462(1997).
RN   [5]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX   PubMed=16738553; DOI=10.1038/msb4100049;
RA   Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA   Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT   "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655
RT   and W3110.";
RL   Mol. Syst. Biol. 2:E1-E5(2006).
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DR   EMBL; M96235; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; L06966; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; U00096; AAC74605.1; -; Genomic_DNA.
DR   EMBL; AP009048; BAA15222.1; -; Genomic_DNA.
DR   PIR; C47072; C47072.
DR   RefSeq; NP_416049.1; NC_000913.3.
DR   RefSeq; WP_000803657.1; NZ_SSZK01000001.1.
DR   AlphaFoldDB; P31121; -.
DR   BioGRID; 4259111; 169.
DR   STRING; 511145.b1532; -.
DR   PaxDb; P31121; -.
DR   EnsemblBacteria; AAC74605; AAC74605; b1532.
DR   EnsemblBacteria; BAA15222; BAA15222; BAA15222.
DR   GeneID; 946184; -.
DR   KEGG; ecj:JW1525; -.
DR   KEGG; eco:b1532; -.
DR   PATRIC; fig|511145.12.peg.1601; -.
DR   EchoBASE; EB1556; -.
DR   eggNOG; ENOG50330WV; Bacteria.
DR   HOGENOM; CLU_194634_0_0_6; -.
DR   OMA; HMGAGSD; -.
DR   PhylomeDB; P31121; -.
DR   BioCyc; EcoCyc:EG11599-MON; -.
DR   PRO; PR:P31121; -.
DR   Proteomes; UP000000318; Chromosome.
DR   Proteomes; UP000000625; Chromosome.
DR   GO; GO:0030288; C:outer membrane-bounded periplasmic space; IDA:EcoCyc.
DR   GO; GO:0046677; P:response to antibiotic; IEA:UniProtKB-KW.
DR   InterPro; IPR025732; MarB.
DR   Pfam; PF13999; MarB; 1.
PE   4: Predicted;
KW   Antibiotic resistance; Reference proteome.
FT   CHAIN           1..72
FT                   /note="Multiple antibiotic resistance protein MarB"
FT                   /id="PRO_0000096241"
SQ   SEQUENCE   72 AA;  7537 MW;  81BFBB2820FF742A CRC64;
     MKPLSSAIAA ALILFSAQGV AEQTTQPVVT SCANVVVVPP SQEHPPFDLN HMGTGSDKSD
     ALGVPYYNQH AM