MARC_ECOL6
ID MARC_ECOL6 Reviewed; 221 AA.
AC Q8FHE5;
DT 22-JUL-2008, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2003, sequence version 1.
DT 03-AUG-2022, entry version 76.
DE RecName: Full=UPF0056 inner membrane protein MarC;
GN Name=marC; OrderedLocusNames=c1951;
OS Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=199310;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CFT073 / ATCC 700928 / UPEC;
RX PubMed=12471157; DOI=10.1073/pnas.252529799;
RA Welch R.A., Burland V., Plunkett G. III, Redford P., Roesch P., Rasko D.,
RA Buckles E.L., Liou S.-R., Boutin A., Hackett J., Stroud D., Mayhew G.F.,
RA Rose D.J., Zhou S., Schwartz D.C., Perna N.T., Mobley H.L.T.,
RA Donnenberg M.S., Blattner F.R.;
RT "Extensive mosaic structure revealed by the complete genome sequence of
RT uropathogenic Escherichia coli.";
RL Proc. Natl. Acad. Sci. U.S.A. 99:17020-17024(2002).
CC -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000250}; Multi-pass
CC membrane protein {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the UPF0056 (MarC) family. {ECO:0000305}.
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DR EMBL; AE014075; AAN80408.1; -; Genomic_DNA.
DR RefSeq; WP_000885042.1; NC_004431.1.
DR AlphaFoldDB; Q8FHE5; -.
DR STRING; 199310.c1951; -.
DR EnsemblBacteria; AAN80408; AAN80408; c1951.
DR KEGG; ecc:c1951; -.
DR eggNOG; COG2095; Bacteria.
DR HOGENOM; CLU_079909_2_0_6; -.
DR OMA; MMAIVML; -.
DR BioCyc; ECOL199310:C1951-MON; -.
DR Proteomes; UP000001410; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR InterPro; IPR002771; Multi_antbiot-R_MarC.
DR PANTHER; PTHR33508; PTHR33508; 1.
DR Pfam; PF01914; MarC; 1.
DR TIGRFAMs; TIGR00427; TIGR00427; 1.
PE 3: Inferred from homology;
KW Cell inner membrane; Cell membrane; Membrane; Transmembrane;
KW Transmembrane helix.
FT CHAIN 1..221
FT /note="UPF0056 inner membrane protein MarC"
FT /id="PRO_0000343819"
FT TOPO_DOM 1..7
FT /note="Periplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 8..28
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 29..44
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 45..65
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 66..68
FT /note="Periplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 69..89
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 90..118
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 119..139
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 140..154
FT /note="Periplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 155..175
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 176..196
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 197..217
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 218..221
FT /note="Periplasmic"
FT /evidence="ECO:0000255"
SQ SEQUENCE 221 AA; 23590 MW; 68AB1298E2391C35 CRC64;
MLDLFKAIGL GLVVLLPLAN PLTTVALFLG LAGNMSSAER NRQSLMASVY VFAIMMVAYY
AGQLVMDTFG ISIPGLRIAG GLIVAFIGFR MLFPQQKAID SPEAKSKSEE LEDEPSANIA
FVPLAMPSTA GPGTIAMIIS SASTVRQSST FADWVLMVAP PLIFFLVAVI LWGSLRSSGA
IMRLVGKGGI EAISRLMGFL LVCMGVQFII NGILEIIKTY H