ID   MATA1_PICAN             Reviewed;         181 AA.
AC   Q707Y6;
DT   01-MAR-2005, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   25-MAY-2022, entry version 60.
DE   RecName: Full=Mating-type protein A1;
DE   AltName: Full=MATa1 transcription factor;
GN   Name=MATA1;
OS   Pichia angusta (Yeast) (Hansenula polymorpha).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Pichiaceae; Ogataea.
OX   NCBI_TaxID=870730;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=ATCC 34438 / CBS 4732 / DSM 70277 / JCM 3621 / NBRC 1476 / NRRL
RC   Y-5445;
RX   PubMed=14745027; DOI=10.1073/pnas.0304170101;
RA   Butler G., Kenny C., Fagan A., Kurischko C., Gaillardin C., Wolfe K.H.;
RT   "Evolution of the MAT locus and its Ho endonuclease in yeast species.";
RL   Proc. Natl. Acad. Sci. U.S.A. 101:1632-1637(2004).
CC   -!- FUNCTION: Mating type proteins are sequence specific DNA-binding
CC       proteins that act as master switches in yeast differentiation by
CC       controlling gene expression in a cell type-specific fashion.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00108}.
CC   -!- MISCELLANEOUS: In P.angusta, all mating-type proteins (MATA1, MATALPHA1
CC       and MATALPHA2) are encoded on one idiomorph, consistent with the fact
CC       that P.angusta is a homothallic haploid in which any strain can mate
CC       with any other strain.
CC   -!- SIMILARITY: Belongs to the MATA1 family. {ECO:0000305}.
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DR   EMBL; AJ617305; CAE84419.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q707Y6; -.
DR   SMR; Q707Y6; -.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IEA:InterPro.
DR   CDD; cd00086; homeodomain; 1.
DR   InterPro; IPR009057; Homeobox-like_sf.
DR   InterPro; IPR017970; Homeobox_CS.
DR   InterPro; IPR001356; Homeobox_dom.
DR   Pfam; PF00046; Homeodomain; 1.
DR   SMART; SM00389; HOX; 1.
DR   SUPFAM; SSF46689; SSF46689; 1.
DR   PROSITE; PS00027; HOMEOBOX_1; 1.
DR   PROSITE; PS50071; HOMEOBOX_2; 1.
PE   3: Inferred from homology;
KW   DNA-binding; Homeobox; Nucleus; Transcription; Transcription regulation.
FT   CHAIN           1..181
FT                   /note="Mating-type protein A1"
FT                   /id="PRO_0000049181"
FT   DNA_BIND        122..181
FT                   /note="Homeobox"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00108"
SQ   SEQUENCE   181 AA;  21048 MW;  6F807AF0A4AB459F CRC64;
     MQFTILNEPS LDSQRREGDL ASENYVFGDI RKEGVRILED SLRSERNALL AIGAGGAADR
     VKQHYRKLLD DWEAAIMEIR SNDKYESLCC GFAIEKAEVE TEMRNTEELD VYKECLVSEC
     FDKKKRRHIP ESSKELLEKA FKVKRFPNSK ERERIARECG ISPLQVRVWF TNKRARSKSR
     A