ID   MATA2_BPSP              Reviewed;         450 AA.
AC   P09676;
DT   01-JUL-1989, integrated into UniProtKB/Swiss-Prot.
DT   01-JUL-1989, sequence version 1.
DT   03-AUG-2022, entry version 70.
DE   RecName: Full=Maturation protein A2;
DE            Short=MP;
DE   AltName: Full=A2;
DE   AltName: Full=Assembly protein;
DE            Short=A protein;
GN   Name=A;
OS   Enterobacteria phage SP (Bacteriophage SP).
OC   Viruses; Riboviria; Orthornavirae; Lenarviricota; Leviviricetes;
OC   Levivirales; Leviviridae; Allolevivirus.
OX   NCBI_TaxID=12027;
OH   NCBI_TaxID=562; Escherichia coli.
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RX   PubMed=3399390; DOI=10.1093/nar/16.13.6205;
RA   Hirashima A., Hirose T., Inayama S., Inokuchi Y., Jacobson A.B.;
RT   "Analysis of the complete nucleotide sequence of the group IV RNA coliphage
RT   SP.";
RL   Nucleic Acids Res. 16:6205-6221(1988).
CC   -!- FUNCTION: Induces host cell lysis. Inhibits host MurA activity thereby
CC       blocking the synthesis of murein precursors necessary for the host cell
CC       wall biosynthesis. May be responsible for the attachment to the host
CC       pilus. {ECO:0000250|UniProtKB:Q8LTE2}.
CC   -!- SUBUNIT: Interacts with host MurA; this interaction inhibits the first
CC       step in host cell wall synthesis. Interacts with the capsid protein
CC       dimers. {ECO:0000250|UniProtKB:Q8LTE2}.
CC   -!- SUBCELLULAR LOCATION: Virion {ECO:0000250|UniProtKB:Q8LTE2}. Note=A
CC       single copy of the maturation protein is present in the virion.
CC       {ECO:0000250|UniProtKB:Q8LTE2}.
CC   -!- SIMILARITY: Belongs to the Levivirus maturation protein family.
CC       {ECO:0000305}.
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DR   EMBL; X07489; CAA30372.1; -; mRNA.
DR   PIR; S01963; S01963.
DR   SMR; P09676; -.
DR   Proteomes; UP000000728; Genome.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0098671; P:adhesion receptor-mediated virion attachment to host cell; IEA:UniProtKB-KW.
DR   GO; GO:0019835; P:cytolysis; IEA:UniProtKB-KW.
DR   GO; GO:0046718; P:viral entry into host cell; IEA:UniProtKB-KW.
DR   GO; GO:0039666; P:virion attachment to host cell pilus; IEA:UniProtKB-KW.
DR   InterPro; IPR005563; A_protein.
DR   Pfam; PF03863; Phage_mat-A; 2.
PE   2: Evidence at transcript level;
KW   Cytolysis; Host cell lysis by virus; Host-virus interaction;
KW   Reference proteome; RNA-binding;
KW   Viral attachment to host adhesion receptor; Viral attachment to host cell;
KW   Viral attachment to host cell pilus; Viral release from host cell; Virion;
KW   Virus entry into host cell.
FT   CHAIN           1..450
FT                   /note="Maturation protein A2"
FT                   /id="PRO_0000164860"
FT   REGION          156..174
FT                   /note="RNA-binding"
FT                   /evidence="ECO:0000250|UniProtKB:Q8LTE2"
FT   REGION          255..265
FT                   /note="RNA-binding"
FT                   /evidence="ECO:0000250|UniProtKB:Q8LTE2"
FT   REGION          321..325
FT                   /note="RNA-binding"
FT                   /evidence="ECO:0000250|UniProtKB:Q8LTE2"
SQ   SEQUENCE   450 AA;  51239 MW;  5F26781A4E3FD888 CRC64;
     MPTLPRGLRF GSNGEVLNDF EALWFPERHT VDLSNGTCKL TGYITNLPGY SDIFPNKGVT
     AARTPYRSTV PVNHLGYRPV TTVEYIPDGT YVRLDGHVKF EGDLVNGSVD LTNFVISLAA
     QGGFDYQSVI GPRFSARFSA FSTKYGVLLG EGRETLKYLL LVVRRMREGY RAVRRGDLKR
     LRNVISTFEP STIKGKRARA EFSQTYRDKL TGNKVEVRPS EGKWNSSSAS DLWLEFRYGL
     MPLFYDIQSV MEDFMRVHKK IAKIQRFSAG HGKLETVSSR FYPDVHFSLE VTAVLQRRHR
     WGVIYQDTGS FATFNNGRLV PVKDWKTAAF ALLNPAEVAW EVTPYSFVVD WFVNVGDMLE
     QMGQLYRHVD VVDGFDRKDI KLKSVSVRVL TNDVAHVASF QLRQAKLLHS YYSRVHTVAF
     PQISPQLDTE IRSVKHVIDS IALLTQRVKR