ID   MATA_BPGA               Reviewed;         390 AA.
AC   P07394;
DT   01-APR-1988, integrated into UniProtKB/Swiss-Prot.
DT   01-APR-1988, sequence version 1.
DT   23-FEB-2022, entry version 76.
DE   RecName: Full=Maturation protein A;
DE            Short=MP;
DE   AltName: Full=Assembly protein;
DE            Short=A protein;
GN   Name=A;
OS   Enterobacteria phage GA (Bacteriophage GA).
OC   Viruses; Riboviria; Orthornavirae; Lenarviricota; Leviviricetes;
OC   Norzivirales; Fiersviridae; Emesvirus; Emesvirus japonicum.
OX   NCBI_TaxID=12018;
OH   NCBI_TaxID=562; Escherichia coli.
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RX   PubMed=3711059; DOI=10.1093/oxfordjournals.jbchem.a135580;
RA   Inokuchi Y., Takahashi R., Hirose T., Inayama S., Jacobson A.B.,
RA   Hirashima A.;
RT   "The complete nucleotide sequence of the group II RNA coliphage GA.";
RL   J. Biochem. 99:1169-1180(1986).
CC   -!- FUNCTION: The maturation protein is required for the typical attachment
CC       of the phage to the side of the bacterial pili. Binds to sequences
CC       located toward each end of the genome, hence circularizing it. The RNA
CC       genome-maturation protein A complex is released from the capsid upon
CC       host receptor binding. Maturation protein A enters the cell along with
CC       the viral RNA. {ECO:0000250|UniProtKB:P03610}.
CC   -!- SUBUNIT: Interacts with the host pilus. {ECO:0000250|UniProtKB:P03610}.
CC   -!- SUBCELLULAR LOCATION: Virion {ECO:0000250|UniProtKB:P03610}. Note=A
CC       single copy of the maturation protein is present in the virion.
CC       {ECO:0000250|UniProtKB:P03610}.
CC   -!- PTM: During internalization, MP is proteolytically cleaved into two
CC       fragments allowing translation and replication to start.
CC       {ECO:0000250|UniProtKB:P03610}.
CC   -!- SIMILARITY: Belongs to the Levivirus maturation protein family.
CC       {ECO:0000305}.
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DR   EMBL; X03869; CAA27496.1; -; mRNA.
DR   PIR; JS0009; ACBPMG.
DR   SMR; P07394; -.
DR   Proteomes; UP000002126; Genome.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046718; P:viral entry into host cell; IEA:UniProtKB-KW.
DR   GO; GO:0099009; P:viral genome circularization; IEA:UniProtKB-KW.
DR   GO; GO:0039666; P:virion attachment to host cell pilus; IEA:UniProtKB-KW.
DR   InterPro; IPR005563; A_protein.
DR   Pfam; PF03863; Phage_mat-A; 1.
PE   2: Evidence at transcript level;
KW   Host-virus interaction; Reference proteome; RNA-binding;
KW   Viral attachment to host cell; Viral attachment to host cell pilus;
KW   Viral genome circularization; Viral penetration into host cytoplasm;
KW   Virion; Virus entry into host cell.
FT   CHAIN           1..390
FT                   /note="Maturation protein A"
FT                   /id="PRO_0000164858"
SQ   SEQUENCE   390 AA;  44385 MW;  B3B86A05209A1735 CRC64;
     MFPKSNIDRN YKVKLISYDK KGKLVSDDSF EQVENYLFQN RSTTYKPGYI RRDFRRPTNF
     WNGYRCFNQP VGTFTRKLSD GGRQVADYGI VNPNKFTANS QHLGDNMVIY PGPFSINIDQ
     RASVEVLNKL SQSNLNIGVA IAEAKMTASL LAKQSIALIR AYTAAKRGNW REVLSQLLIS
     EHRFRAPAKD LGGRWLELQY GWLPLMSDLK AAYDLLTQTK LPAFMPLRVT RTVGGTHNYK
     VRNVESAGDT WSYRHRLSVN YRIWYFISDP RLAWASSLGL LNPLEIYWEK TPWSFVVDWF
     LPVGNLIEAM SNPLGLDIIS GTKTWQLESK LNATLPASGW SGTAKLTAYA KAYDRSTFYS
     FPTPLPYVKS PLSGLHLANA LALINQRLKR