MATA_LYSSH
ID MATA_LYSSH Reviewed; 180 AA.
AC P26840;
DT 01-AUG-1992, integrated into UniProtKB/Swiss-Prot.
DT 01-AUG-1992, sequence version 1.
DT 25-MAY-2022, entry version 63.
DE RecName: Full=Probable macrolide acetyltransferase;
DE EC=2.3.1.-;
DE Flags: Fragment;
OS Lysinibacillus sphaericus (Bacillus sphaericus).
OC Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Lysinibacillus.
OX NCBI_TaxID=1421;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=3025178; DOI=10.1128/jb.169.1.340-350.1987;
RA Monod M., Mohan S., Dubnau D.;
RT "Cloning and analysis of ermG, a new macrolide-lincosamide-streptogramin B
RT resistance element from Bacillus sphaericus.";
RL J. Bacteriol. 169:340-350(1987).
CC -!- SIMILARITY: Belongs to the transferase hexapeptide repeat family.
CC {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAA22417.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR EMBL; M15332; AAA22417.1; ALT_INIT; Genomic_DNA.
DR PIR; A26930; A26930.
DR AlphaFoldDB; P26840; -.
DR SMR; P26840; -.
DR GO; GO:0016746; F:acyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0046677; P:response to antibiotic; IEA:UniProtKB-KW.
DR InterPro; IPR001451; Hexapep.
DR InterPro; IPR018357; Hexapep_transf_CS.
DR InterPro; IPR011004; Trimer_LpxA-like_sf.
DR Pfam; PF00132; Hexapep; 1.
DR SUPFAM; SSF51161; SSF51161; 1.
DR PROSITE; PS00101; HEXAPEP_TRANSFERASES; 1.
PE 3: Inferred from homology;
KW Acyltransferase; Antibiotic resistance; Repeat; Transferase.
FT CHAIN <1..180
FT /note="Probable macrolide acetyltransferase"
FT /id="PRO_0000068662"
FT NON_TER 1
SQ SEQUENCE 180 AA; 20399 MW; 7EDF56157EF63B1A CRC64;
DHKNSPEKFY DNIEHHYEFI GDKLIIGKFC AIAEGVKFIM NGANHRMDGI TTYPFNIFGC
GWEKVTPTIE QLPFKGDTVI GNDVWIGQNV TIMPGVIIGD GAIIAANSTV VKSVEPYSIY
SGNPAKFIKK RFSDEKIEFL LKLEWWNWSG EEIFDNLEIL TSEAGLEELM NKYSKRDAIN