ARGLA_DANRE
ID ARGLA_DANRE Reviewed; 251 AA.
AC Q6P5L7; B0UY72; Q803Q3;
DT 29-MAY-2007, integrated into UniProtKB/Swiss-Prot.
DT 05-JUL-2004, sequence version 1.
DT 03-AUG-2022, entry version 80.
DE RecName: Full=Arginine and glutamate-rich protein 1-A;
GN Name=arglu1a; ORFNames=si:ch211-149b20.2, zgc:55375;
OS Danio rerio (Zebrafish) (Brachydanio rerio).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC Danionidae; Danioninae; Danio.
OX NCBI_TaxID=7955;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Tuebingen;
RX PubMed=23594743; DOI=10.1038/nature12111;
RA Howe K., Clark M.D., Torroja C.F., Torrance J., Berthelot C., Muffato M.,
RA Collins J.E., Humphray S., McLaren K., Matthews L., McLaren S., Sealy I.,
RA Caccamo M., Churcher C., Scott C., Barrett J.C., Koch R., Rauch G.J.,
RA White S., Chow W., Kilian B., Quintais L.T., Guerra-Assuncao J.A., Zhou Y.,
RA Gu Y., Yen J., Vogel J.H., Eyre T., Redmond S., Banerjee R., Chi J., Fu B.,
RA Langley E., Maguire S.F., Laird G.K., Lloyd D., Kenyon E., Donaldson S.,
RA Sehra H., Almeida-King J., Loveland J., Trevanion S., Jones M., Quail M.,
RA Willey D., Hunt A., Burton J., Sims S., McLay K., Plumb B., Davis J.,
RA Clee C., Oliver K., Clark R., Riddle C., Elliot D., Threadgold G.,
RA Harden G., Ware D., Begum S., Mortimore B., Kerry G., Heath P.,
RA Phillimore B., Tracey A., Corby N., Dunn M., Johnson C., Wood J., Clark S.,
RA Pelan S., Griffiths G., Smith M., Glithero R., Howden P., Barker N.,
RA Lloyd C., Stevens C., Harley J., Holt K., Panagiotidis G., Lovell J.,
RA Beasley H., Henderson C., Gordon D., Auger K., Wright D., Collins J.,
RA Raisen C., Dyer L., Leung K., Robertson L., Ambridge K., Leongamornlert D.,
RA McGuire S., Gilderthorp R., Griffiths C., Manthravadi D., Nichol S.,
RA Barker G., Whitehead S., Kay M., Brown J., Murnane C., Gray E.,
RA Humphries M., Sycamore N., Barker D., Saunders D., Wallis J., Babbage A.,
RA Hammond S., Mashreghi-Mohammadi M., Barr L., Martin S., Wray P.,
RA Ellington A., Matthews N., Ellwood M., Woodmansey R., Clark G., Cooper J.,
RA Tromans A., Grafham D., Skuce C., Pandian R., Andrews R., Harrison E.,
RA Kimberley A., Garnett J., Fosker N., Hall R., Garner P., Kelly D., Bird C.,
RA Palmer S., Gehring I., Berger A., Dooley C.M., Ersan-Urun Z., Eser C.,
RA Geiger H., Geisler M., Karotki L., Kirn A., Konantz J., Konantz M.,
RA Oberlander M., Rudolph-Geiger S., Teucke M., Lanz C., Raddatz G.,
RA Osoegawa K., Zhu B., Rapp A., Widaa S., Langford C., Yang F.,
RA Schuster S.C., Carter N.P., Harrow J., Ning Z., Herrero J., Searle S.M.,
RA Enright A., Geisler R., Plasterk R.H., Lee C., Westerfield M.,
RA de Jong P.J., Zon L.I., Postlethwait J.H., Nusslein-Volhard C.,
RA Hubbard T.J., Roest Crollius H., Rogers J., Stemple D.L.;
RT "The zebrafish reference genome sequence and its relationship to the human
RT genome.";
RL Nature 496:498-503(2013).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=AB;
RG NIH - Zebrafish Gene Collection (ZGC) project;
RL Submitted (NOV-2003) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the UPF0430 family. {ECO:0000305}.
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DR EMBL; CR391949; CAQ15594.1; -; Genomic_DNA.
DR EMBL; BC044383; AAH44383.1; -; mRNA.
DR EMBL; BC062839; AAH62839.1; -; mRNA.
DR RefSeq; NP_998381.2; NM_213216.2.
DR AlphaFoldDB; Q6P5L7; -.
DR STRING; 7955.ENSDARP00000013189; -.
DR PaxDb; Q6P5L7; -.
DR PRIDE; Q6P5L7; -.
DR Ensembl; ENSDART00000011910; ENSDARP00000013189; ENSDARG00000019223.
DR GeneID; 406834; -.
DR KEGG; dre:406834; -.
DR CTD; 406834; -.
DR ZFIN; ZDB-GENE-040426-2914; arglu1a.
DR eggNOG; ENOG502QPR5; Eukaryota.
DR GeneTree; ENSGT00730000111249; -.
DR HOGENOM; CLU_076749_0_0_1; -.
DR InParanoid; Q6P5L7; -.
DR OMA; DRRYRKD; -.
DR OrthoDB; 1645445at2759; -.
DR TreeFam; TF324123; -.
DR PRO; PR:Q6P5L7; -.
DR Proteomes; UP000000437; Genome assembly.
DR Proteomes; UP000814640; Chromosome 9.
DR Bgee; ENSDARG00000019223; Expressed in brain and 28 other tissues.
DR GO; GO:0005739; C:mitochondrion; IBA:GO_Central.
DR GO; GO:0005654; C:nucleoplasm; IBA:GO_Central.
DR InterPro; IPR033371; ARGLU1.
DR PANTHER; PTHR31711; PTHR31711; 1.
DR Pfam; PF15346; ARGLU; 1.
PE 2: Evidence at transcript level;
KW Reference proteome.
FT CHAIN 1..251
FT /note="Arginine and glutamate-rich protein 1-A"
FT /id="PRO_0000288443"
FT REGION 1..92
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 215..251
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..48
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 49..92
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 215..236
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CONFLICT 66
FT /note="R -> W (in Ref. 2; AAH44383)"
FT /evidence="ECO:0000305"
FT CONFLICT 157
FT /note="Q -> L (in Ref. 2; AAH44383)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 251 AA; 30422 MW; 82783C12CF15550A CRC64;
MGRSRSRSSS RSKHSKHSRK RSRSKSKSKK RSRSKEPKRN RRSRSRSGSR RDRGGSPPDR
TDMFGRTLSK RNNDEKQKRE EEDRRVEIER QRKIRQQEIE ERLIEEETAR RVEELVARRV
EEELEKRRDE IEHEVLRRVE EAKRIMEAQL LQELERQRQA ELNAQKAREE EEKSKRVELE
RILEENNRKI ADAQAKLAED QLRIVEEQRK IHEERMKLEQ ERQKQQKEEQ KMILGKGKSR
PRLSFSLKAT E