ARGOS_ARATH
ID ARGOS_ARATH Reviewed; 130 AA.
AC Q6NMD6; Q9M1Y4;
DT 16-OCT-2013, integrated into UniProtKB/Swiss-Prot.
DT 05-JUL-2004, sequence version 1.
DT 25-MAY-2022, entry version 101.
DE RecName: Full=Protein AUXIN-REGULATED GENE INVOLVED IN ORGAN SIZE;
DE Short=AtARGOS;
GN Name=ARGOS; OrderedLocusNames=At3g59900; ORFNames=F24G16.170;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA], FUNCTION, DISRUPTION PHENOTYPE, INDUCTION BY
RP AUXIN, TISSUE SPECIFICITY, DEVELOPMENTAL STAGE, AND SUBCELLULAR LOCATION.
RC STRAIN=cv. Columbia;
RX PubMed=12953103; DOI=10.1105/tpc.013557;
RA Hu Y., Xie Q., Chua N.-H.;
RT "The Arabidopsis auxin-inducible gene ARGOS controls lateral organ size.";
RL Plant Cell 15:1951-1961(2003).
RN [2]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=cv. Ag-0, cv. An-1, cv. Br-0, cv. C24, cv. Edi-0, cv. Kin-0,
RC cv. Landsberg erecta, cv. Ll-0, cv. Ms-0, cv. Mt-0, cv. Nd-1, cv. Nok-3,
RC cv. Oy-0, cv. Se-0, and cv. Wa-1;
RX PubMed=17435248; DOI=10.1534/genetics.107.071928;
RA Ehrenreich I.M., Stafford P.A., Purugganan M.D.;
RT "The genetic architecture of shoot branching in Arabidopsis thaliana: a
RT comparative assessment of candidate gene associations vs. quantitative
RT trait locus mapping.";
RL Genetics 176:1223-1236(2007).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130713; DOI=10.1038/35048706;
RA Salanoubat M., Lemcke K., Rieger M., Ansorge W., Unseld M., Fartmann B.,
RA Valle G., Bloecker H., Perez-Alonso M., Obermaier B., Delseny M.,
RA Boutry M., Grivell L.A., Mache R., Puigdomenech P., De Simone V.,
RA Choisne N., Artiguenave F., Robert C., Brottier P., Wincker P.,
RA Cattolico L., Weissenbach J., Saurin W., Quetier F., Schaefer M.,
RA Mueller-Auer S., Gabel C., Fuchs M., Benes V., Wurmbach E., Drzonek H.,
RA Erfle H., Jordan N., Bangert S., Wiedelmann R., Kranz H., Voss H.,
RA Holland R., Brandt P., Nyakatura G., Vezzi A., D'Angelo M., Pallavicini A.,
RA Toppo S., Simionati B., Conrad A., Hornischer K., Kauer G., Loehnert T.-H.,
RA Nordsiek G., Reichelt J., Scharfe M., Schoen O., Bargues M., Terol J.,
RA Climent J., Navarro P., Collado C., Perez-Perez A., Ottenwaelder B.,
RA Duchemin D., Cooke R., Laudie M., Berger-Llauro C., Purnelle B., Masuy D.,
RA de Haan M., Maarse A.C., Alcaraz J.-P., Cottet A., Casacuberta E.,
RA Monfort A., Argiriou A., Flores M., Liguori R., Vitale D., Mannhaupt G.,
RA Haase D., Schoof H., Rudd S., Zaccaria P., Mewes H.-W., Mayer K.F.X.,
RA Kaul S., Town C.D., Koo H.L., Tallon L.J., Jenkins J., Rooney T., Rizzo M.,
RA Walts A., Utterback T., Fujii C.Y., Shea T.P., Creasy T.H., Haas B.,
RA Maiti R., Wu D., Peterson J., Van Aken S., Pai G., Militscher J.,
RA Sellers P., Gill J.E., Feldblyum T.V., Preuss D., Lin X., Nierman W.C.,
RA Salzberg S.L., White O., Venter J.C., Fraser C.M., Kaneko T., Nakamura Y.,
RA Sato S., Kato T., Asamizu E., Sasamoto S., Kimura T., Idesawa K.,
RA Kawashima K., Kishida Y., Kiyokawa C., Kohara M., Matsumoto M., Matsuno A.,
RA Muraki A., Nakayama S., Nakazaki N., Shinpo S., Takeuchi C., Wada T.,
RA Watanabe A., Yamada M., Yasuda M., Tabata S.;
RT "Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana.";
RL Nature 408:820-822(2000).
RN [4]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Cheuk R.F., Chen H., Kim C.J., Shinn P., Carninci P., Hayashizaki Y.,
RA Ishida J., Kamiya A., Kawai J., Narusaka M., Sakurai T., Satou M., Seki M.,
RA Shinozaki K., Ecker J.R.;
RT "Arabidopsis ORF clones.";
RL Submitted (MAR-2004) to the EMBL/GenBank/DDBJ databases.
RN [6]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A.,
RA Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y.,
RA Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K.,
RA Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y.,
RA Shinozaki K.;
RT "Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs.";
RL Submitted (SEP-2004) to the EMBL/GenBank/DDBJ databases.
RN [7]
RP FUNCTION, DISRUPTION PHENOTYPE, AND SUBCELLULAR LOCATION.
RC STRAIN=cv. Columbia;
RX PubMed=21457262; DOI=10.1111/j.1469-8137.2011.03710.x;
RA Feng G., Qin Z., Yan J., Zhang X., Hu Y.;
RT "Arabidopsis ORGAN SIZE RELATED1 regulates organ growth and final organ
RT size in orchestration with ARGOS and ARL.";
RL New Phytol. 191:635-646(2011).
RN [8]
RP INDUCTION BY ETHYLENE.
RX PubMed=23134674; DOI=10.1186/1471-2229-12-208;
RA Markakis M.N., De Cnodder T., Lewandowski M., Simon D., Boron A.,
RA Balcerowicz D., Doubbo T., Taconnat L., Renou J.P., Hoefte H.,
RA Verbelen J.P., Vissenberg K.;
RT "Identification of genes involved in the ACC-mediated control of root cell
RT elongation in Arabidopsis thaliana.";
RL BMC Plant Biol. 12:208-208(2012).
CC -!- FUNCTION: Promotes cell proliferation-dependent organ growth. Takes
CC part in the AXR1-dependent auxin signaling pathway that requires ANT
CC during organogenesis. {ECO:0000269|PubMed:12953103,
CC ECO:0000269|PubMed:21457262}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000250|UniProtKB:Q7X6L2}; Multi-
CC pass membrane protein {ECO:0000250|UniProtKB:Q7X6L2}. Nucleus
CC {ECO:0000269|PubMed:12953103}. Cytoplasm {ECO:0000269|PubMed:12953103}.
CC Endoplasmic reticulum {ECO:0000269|PubMed:21457262}.
CC -!- TISSUE SPECIFICITY: Mostly expressed in flowers, inflorescence stems,
CC leaf primordia and young leaves, and, to a lower extent, in siliques,
CC cotyledon vascular bundles, roots (pericycle and root tips) and mature
CC leaves. {ECO:0000269|PubMed:12953103}.
CC -!- DEVELOPMENTAL STAGE: In flowers, accumulates in stamen filaments as
CC well as in the apices and bases of juvenile and elongating siliques.
CC Present in leaf primordia. {ECO:0000269|PubMed:12953103}.
CC -!- INDUCTION: By auxin and ethylene (1-aminocyclopropane-1-carboxylic acid
CC (ACC)). {ECO:0000269|PubMed:12953103, ECO:0000269|PubMed:23134674}.
CC -!- DOMAIN: The OSR domain is sufficient to promote organ growth.
CC {ECO:0000250}.
CC -!- DISRUPTION PHENOTYPE: Reduced aerial organs mainly due to changes in
CC cell number and the duration of organ growth. When associated with ORS1
CC disruption, reduction in organ size. {ECO:0000269|PubMed:12953103,
CC ECO:0000269|PubMed:21457262}.
CC -!- SIMILARITY: Belongs to the plant organ size related (OSR) protein
CC family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAQ64004.1; Type=Erroneous initiation; Note=Truncated N-terminus.; Evidence={ECO:0000305};
CC Sequence=CAB75809.1; Type=Erroneous initiation; Note=Truncated N-terminus.; Evidence={ECO:0000305};
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DR EMBL; AY305869; AAQ64004.1; ALT_INIT; mRNA.
DR EMBL; EF597812; ABQ85109.1; -; Genomic_DNA.
DR EMBL; EF597813; ABQ85110.1; -; Genomic_DNA.
DR EMBL; EF597814; ABQ85111.1; -; Genomic_DNA.
DR EMBL; EF597815; ABQ85112.1; -; Genomic_DNA.
DR EMBL; EF597816; ABQ85113.1; -; Genomic_DNA.
DR EMBL; EF597817; ABQ85114.1; -; Genomic_DNA.
DR EMBL; EF597818; ABQ85115.1; -; Genomic_DNA.
DR EMBL; EF597819; ABQ85116.1; -; Genomic_DNA.
DR EMBL; EF597820; ABQ85117.1; -; Genomic_DNA.
DR EMBL; EF597821; ABQ85118.1; -; Genomic_DNA.
DR EMBL; EF597822; ABQ85119.1; -; Genomic_DNA.
DR EMBL; EF597824; ABQ85121.1; -; Genomic_DNA.
DR EMBL; EF597825; ABQ85122.1; -; Genomic_DNA.
DR EMBL; EF597826; ABQ85123.1; -; Genomic_DNA.
DR EMBL; EF597827; ABQ85124.1; -; Genomic_DNA.
DR EMBL; AL138647; CAB75809.1; ALT_INIT; Genomic_DNA.
DR EMBL; CP002686; AEE79983.1; -; Genomic_DNA.
DR EMBL; BT011724; AAS49087.1; -; mRNA.
DR EMBL; AK176640; BAD44403.1; -; mRNA.
DR PIR; T47814; T47814.
DR RefSeq; NP_191549.2; NM_115853.5.
DR AlphaFoldDB; Q6NMD6; -.
DR BioGRID; 10474; 32.
DR IntAct; Q6NMD6; 32.
DR STRING; 3702.AT3G59900.1; -.
DR PaxDb; Q6NMD6; -.
DR PRIDE; Q6NMD6; -.
DR ProteomicsDB; 240613; -.
DR EnsemblPlants; AT3G59900.1; AT3G59900.1; AT3G59900.
DR GeneID; 825160; -.
DR Gramene; AT3G59900.1; AT3G59900.1; AT3G59900.
DR KEGG; ath:AT3G59900; -.
DR Araport; AT3G59900; -.
DR TAIR; locus:2080497; AT3G59900.
DR eggNOG; ENOG502S4R4; Eukaryota.
DR HOGENOM; CLU_132308_2_0_1; -.
DR InParanoid; Q6NMD6; -.
DR OMA; RKNMSFR; -.
DR OrthoDB; 1543336at2759; -.
DR PhylomeDB; Q6NMD6; -.
DR PRO; PR:Q6NMD6; -.
DR Proteomes; UP000006548; Chromosome 3.
DR ExpressionAtlas; Q6NMD6; baseline and differential.
DR Genevisible; Q6NMD6; AT.
DR GO; GO:0005737; C:cytoplasm; IDA:UniProtKB.
DR GO; GO:0005783; C:endoplasmic reticulum; IDA:TAIR.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0016020; C:membrane; IDA:UniProtKB.
DR GO; GO:0005634; C:nucleus; IDA:UniProtKB.
DR GO; GO:0071369; P:cellular response to ethylene stimulus; IEP:UniProtKB.
DR GO; GO:0046622; P:positive regulation of organ growth; IMP:TAIR.
DR GO; GO:0042127; P:regulation of cell population proliferation; IMP:TAIR.
DR GO; GO:0048638; P:regulation of developmental growth; IMP:TAIR.
DR GO; GO:0009733; P:response to auxin; IEP:TAIR.
DR InterPro; IPR037468; ARGOS/ARL/OSR1.
DR PANTHER; PTHR36023; PTHR36023; 1.
PE 2: Evidence at transcript level;
KW Cytoplasm; Developmental protein; Endoplasmic reticulum; Membrane; Nucleus;
KW Reference proteome; Transmembrane; Transmembrane helix.
FT CHAIN 1..130
FT /note="Protein AUXIN-REGULATED GENE INVOLVED IN ORGAN SIZE"
FT /id="PRO_0000423596"
FT TRANSMEM 70..90
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 94..114
FT /note="Helical"
FT /evidence="ECO:0000255"
FT REGION 65..116
FT /note="Organ Size Related (OSR) domain"
FT /evidence="ECO:0000250"
SQ SEQUENCE 130 AA; 14695 MW; 231A8D9B946BC08C CRC64;
MIREISNLQK DIINIQDSYS NNRVMDVGRN NRKNMSFRSS PEKSKQELRR SFSAQKRMMI
PANYFSLESL FLLVGLTASL LILPLVLPPL PPPPFMLLLV PIGIMVLLVV LAFMPSSHSN
ANTDVTCNFM
