ARGO_SALCH
ID ARGO_SALCH Reviewed; 211 AA.
AC Q57K48;
DT 25-OCT-2005, integrated into UniProtKB/Swiss-Prot.
DT 10-MAY-2005, sequence version 1.
DT 03-AUG-2022, entry version 74.
DE RecName: Full=Arginine exporter protein ArgO {ECO:0000255|HAMAP-Rule:MF_01901};
GN Name=argO {ECO:0000255|HAMAP-Rule:MF_01901}; OrderedLocusNames=SCH_3008;
OS Salmonella choleraesuis (strain SC-B67).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Salmonella.
OX NCBI_TaxID=321314;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SC-B67;
RX PubMed=15781495; DOI=10.1093/nar/gki297;
RA Chiu C.-H., Tang P., Chu C., Hu S., Bao Q., Yu J., Chou Y.-Y., Wang H.-S.,
RA Lee Y.-S.;
RT "The genome sequence of Salmonella enterica serovar Choleraesuis, a highly
RT invasive and resistant zoonotic pathogen.";
RL Nucleic Acids Res. 33:1690-1698(2005).
CC -!- FUNCTION: Involved in the export of arginine. Important to control the
CC intracellular level of arginine and the correct balance between
CC arginine and lysine. {ECO:0000255|HAMAP-Rule:MF_01901}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=L-arginine(in) = L-arginine(out); Xref=Rhea:RHEA:32143,
CC ChEBI:CHEBI:32682; Evidence={ECO:0000255|HAMAP-Rule:MF_01901};
CC PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:32144;
CC Evidence={ECO:0000255|HAMAP-Rule:MF_01901};
CC -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC Rule:MF_01901}; Multi-pass membrane protein {ECO:0000255|HAMAP-
CC Rule:MF_01901}.
CC -!- SIMILARITY: Belongs to the LysE/ArgO transporter (TC 2.A.75) family.
CC {ECO:0000255|HAMAP-Rule:MF_01901}.
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DR EMBL; AE017220; AAX66914.1; -; Genomic_DNA.
DR RefSeq; WP_001540865.1; NC_006905.1.
DR AlphaFoldDB; Q57K48; -.
DR EnsemblBacteria; AAX66914; AAX66914; SCH_3008.
DR KEGG; sec:SCH_3008; -.
DR HOGENOM; CLU_087840_0_1_6; -.
DR OMA; FARPRAW; -.
DR Proteomes; UP000000538; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0061459; F:L-arginine transmembrane transporter activity; IEA:InterPro.
DR HAMAP; MF_01901; ArgO; 1.
DR InterPro; IPR023445; Arg_export_ArgO_enterobac.
DR InterPro; IPR001123; LeuE-type.
DR InterPro; IPR004777; Lys/arg_exporter.
DR PANTHER; PTHR30086; PTHR30086; 1.
DR Pfam; PF01810; LysE; 1.
DR TIGRFAMs; TIGR00948; 2a75; 1.
PE 3: Inferred from homology;
KW Amino-acid transport; Cell inner membrane; Cell membrane; Membrane;
KW Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..211
FT /note="Arginine exporter protein ArgO"
FT /id="PRO_0000204163"
FT TRANSMEM 1..21
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01901"
FT TRANSMEM 37..57
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01901"
FT TRANSMEM 68..88
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01901"
FT TRANSMEM 111..131
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01901"
FT TRANSMEM 147..167
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01901"
FT TRANSMEM 179..199
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01901"
SQ SEQUENCE 211 AA; 23239 MW; 64D6E26F0B3F1D0F CRC64;
MISYYFQGFA LGAAMILPLG PQNAFVMNQG IRRQYHLMIA LLCALSDLVL ISAGIFGGSA
LLMQSPWLLA LVTWGGVAFL LWYGFGALKT AMSSNLELAS AEVMKQGRWK IIATMLAVTW
LNPHVYLDTF VVLGSLGGQL AMEPKRWFAL GTISASFLWF FGLALLAAWL APRLRTVKAQ
RIINILVGVV MWLIAFQLAR EGVAHMQALF N