位置:首页 > 蛋白库 > ARGO_SALHS
ARGO_SALHS
ID   ARGO_SALHS              Reviewed;         211 AA.
AC   B4THE9;
DT   28-JUL-2009, integrated into UniProtKB/Swiss-Prot.
DT   23-SEP-2008, sequence version 1.
DT   03-AUG-2022, entry version 64.
DE   RecName: Full=Arginine exporter protein ArgO {ECO:0000255|HAMAP-Rule:MF_01901};
GN   Name=argO {ECO:0000255|HAMAP-Rule:MF_01901}; OrderedLocusNames=SeHA_C3302;
OS   Salmonella heidelberg (strain SL476).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Salmonella.
OX   NCBI_TaxID=454169;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SL476;
RX   PubMed=21602358; DOI=10.1128/jb.00297-11;
RA   Fricke W.F., Mammel M.K., McDermott P.F., Tartera C., White D.G.,
RA   Leclerc J.E., Ravel J., Cebula T.A.;
RT   "Comparative genomics of 28 Salmonella enterica isolates: evidence for
RT   CRISPR-mediated adaptive sublineage evolution.";
RL   J. Bacteriol. 193:3556-3568(2011).
CC   -!- FUNCTION: Involved in the export of arginine. Important to control the
CC       intracellular level of arginine and the correct balance between
CC       arginine and lysine. {ECO:0000255|HAMAP-Rule:MF_01901}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=L-arginine(in) = L-arginine(out); Xref=Rhea:RHEA:32143,
CC         ChEBI:CHEBI:32682; Evidence={ECO:0000255|HAMAP-Rule:MF_01901};
CC       PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:32144;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_01901};
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC       Rule:MF_01901}; Multi-pass membrane protein {ECO:0000255|HAMAP-
CC       Rule:MF_01901}.
CC   -!- SIMILARITY: Belongs to the LysE/ArgO transporter (TC 2.A.75) family.
CC       {ECO:0000255|HAMAP-Rule:MF_01901}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CP001120; ACF66812.1; -; Genomic_DNA.
DR   RefSeq; WP_000626863.1; NC_011083.1.
DR   AlphaFoldDB; B4THE9; -.
DR   KEGG; seh:SeHA_C3302; -.
DR   HOGENOM; CLU_087840_0_1_6; -.
DR   OMA; FARPRAW; -.
DR   Proteomes; UP000001866; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0061459; F:L-arginine transmembrane transporter activity; IEA:InterPro.
DR   HAMAP; MF_01901; ArgO; 1.
DR   InterPro; IPR023445; Arg_export_ArgO_enterobac.
DR   InterPro; IPR001123; LeuE-type.
DR   InterPro; IPR004777; Lys/arg_exporter.
DR   PANTHER; PTHR30086; PTHR30086; 1.
DR   Pfam; PF01810; LysE; 1.
DR   TIGRFAMs; TIGR00948; 2a75; 1.
PE   3: Inferred from homology;
KW   Amino-acid transport; Cell inner membrane; Cell membrane; Membrane;
KW   Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..211
FT                   /note="Arginine exporter protein ArgO"
FT                   /id="PRO_1000188721"
FT   TRANSMEM        1..21
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01901"
FT   TRANSMEM        37..57
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01901"
FT   TRANSMEM        68..88
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01901"
FT   TRANSMEM        111..131
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01901"
FT   TRANSMEM        147..167
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01901"
FT   TRANSMEM        179..199
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01901"
SQ   SEQUENCE   211 AA;  23220 MW;  64D6FC8FF21F1D0F CRC64;
     MISYYFQGFA LGAAMILPLG PQNAFVMNQG IRRQYHLMIA LLCALSDLVL ISAGIFGGSA
     LLMQSPWLLA LVTWGGVAFL LWYGFGALKT AMSSNLELAS AEVMKQGRWK IIATMLAVTW
     LNPHVYLDTF VVLGSLGGQL AMEPKRWFAL GTISASFLWF FGLALLAAWL APRLRTAKAQ
     RIINILVGVV MWLIAFQLAR EGVAHMHALF N
 
 
维奥蛋白资源库 - 中文蛋白资源 CopyRight © 2010-2024