ID   ARGO_SALPC              Reviewed;         211 AA.
AC   C0PY41;
DT   28-JUL-2009, integrated into UniProtKB/Swiss-Prot.
DT   05-MAY-2009, sequence version 1.
DT   03-AUG-2022, entry version 55.
DE   RecName: Full=Arginine exporter protein ArgO {ECO:0000255|HAMAP-Rule:MF_01901};
GN   Name=argO {ECO:0000255|HAMAP-Rule:MF_01901}; OrderedLocusNames=SPC_3128;
OS   Salmonella paratyphi C (strain RKS4594).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Salmonella.
OX   NCBI_TaxID=476213;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=RKS4594;
RX   PubMed=19229335; DOI=10.1371/journal.pone.0004510;
RA   Liu W.-Q., Feng Y., Wang Y., Zou Q.-H., Chen F., Guo J.-T., Peng Y.-H.,
RA   Jin Y., Li Y.-G., Hu S.-N., Johnston R.N., Liu G.-R., Liu S.-L.;
RT   "Salmonella paratyphi C: genetic divergence from Salmonella choleraesuis
RT   and pathogenic convergence with Salmonella typhi.";
RL   PLoS ONE 4:E4510-E4510(2009).
CC   -!- FUNCTION: Involved in the export of arginine. Important to control the
CC       intracellular level of arginine and the correct balance between
CC       arginine and lysine. {ECO:0000255|HAMAP-Rule:MF_01901}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=L-arginine(in) = L-arginine(out); Xref=Rhea:RHEA:32143,
CC         ChEBI:CHEBI:32682; Evidence={ECO:0000255|HAMAP-Rule:MF_01901};
CC       PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:32144;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_01901};
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC       Rule:MF_01901}; Multi-pass membrane protein {ECO:0000255|HAMAP-
CC       Rule:MF_01901}.
CC   -!- SIMILARITY: Belongs to the LysE/ArgO transporter (TC 2.A.75) family.
CC       {ECO:0000255|HAMAP-Rule:MF_01901}.
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DR   EMBL; CP000857; ACN47215.1; -; Genomic_DNA.
DR   RefSeq; WP_000626864.1; NC_012125.1.
DR   AlphaFoldDB; C0PY41; -.
DR   EnsemblBacteria; ACN47215; ACN47215; SPC_3128.
DR   KEGG; sei:SPC_3128; -.
DR   HOGENOM; CLU_087840_0_1_6; -.
DR   OMA; FARPRAW; -.
DR   Proteomes; UP000001599; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0061459; F:L-arginine transmembrane transporter activity; IEA:InterPro.
DR   HAMAP; MF_01901; ArgO; 1.
DR   InterPro; IPR023445; Arg_export_ArgO_enterobac.
DR   InterPro; IPR001123; LeuE-type.
DR   InterPro; IPR004777; Lys/arg_exporter.
DR   PANTHER; PTHR30086; PTHR30086; 1.
DR   Pfam; PF01810; LysE; 1.
DR   TIGRFAMs; TIGR00948; 2a75; 1.
PE   3: Inferred from homology;
KW   Amino-acid transport; Cell inner membrane; Cell membrane; Membrane;
KW   Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..211
FT                   /note="Arginine exporter protein ArgO"
FT                   /id="PRO_1000188723"
FT   TRANSMEM        1..21
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01901"
FT   TRANSMEM        37..57
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01901"
FT   TRANSMEM        68..88
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01901"
FT   TRANSMEM        111..131
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01901"
FT   TRANSMEM        147..167
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01901"
FT   TRANSMEM        179..199
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01901"
SQ   SEQUENCE   211 AA;  23248 MW;  64D6E26F1C0F1D0F CRC64;
     MISYYFQGFA LGAAMILPLG PQNAFVMNQG IRRQYHLMIA LLCALSDLVL ISAGIFGGSA
     LLMQSPWLLA LVTWGGVAFL LWYGFGALKT AMSSNLELAS AEVMKQGRWK IIATMLAVTW
     LNPHVYLDTF VVLGSLGGQL AMEPKRWFAL GTISASFLWF FGLALLAAWL APRLRTVKAQ
     RIINILVGVV MWLIAFQLAR EGVAHMHALF N