MATMI_SCHPO
ID MATMI_SCHPO Reviewed; 42 AA.
AC P0CY15; P10839;
DT 28-JUN-2011, integrated into UniProtKB/Swiss-Prot.
DT 28-JUN-2011, sequence version 1.
DT 25-MAY-2022, entry version 48.
DE RecName: Full=Mating-type M-specific polypeptide Mi;
GN Name=mat1-Mi; Synonyms=mat1-Mm, matMi; ORFNames=SPBC23G7.17c;
OS Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC Schizosaccharomyces.
OX NCBI_TaxID=284812;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=972 / ATCC 24843;
RX PubMed=11859360; DOI=10.1038/nature724;
RA Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA Nurse P.;
RT "The genome sequence of Schizosaccharomyces pombe.";
RL Nature 415:871-880(2002).
RN [2]
RP FUNCTION.
RX PubMed=2900761; DOI=10.1002/j.1460-2075.1988.tb02973.x;
RA Kelly M., Burke J., Smith M., Klar A., Beach D.;
RT "Four mating-type genes control sexual differentiation in the fission
RT yeast.";
RL EMBO J. 7:1537-1547(1988).
RN [3]
RP SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
RX PubMed=16823372; DOI=10.1038/nbt1222;
RA Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S.,
RA Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S.,
RA Yoshida M.;
RT "ORFeome cloning and global analysis of protein localization in the fission
RT yeast Schizosaccharomyces pombe.";
RL Nat. Biotechnol. 24:841-847(2006).
CC -!- FUNCTION: Mating type proteins are sequence specific DNA-binding
CC proteins that act as master switches in yeast differentiation by
CC controlling gene expression in a cell type-specific fashion. Required
CC for meiosis, but plays no role in conjugation.
CC {ECO:0000269|PubMed:2900761}.
CC -!- INTERACTION:
CC P0CY15; P10842: mat2-Pi; Xeno; NbExp=2; IntAct=EBI-20725384, EBI-20725367;
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:16823372}. Nucleus
CC {ECO:0000269|PubMed:16823372}.
CC -!- MISCELLANEOUS: There are three genetic loci for mating type genes in
CC S.pombe, mat1, mat2-P and mat3-M. Cell type is determined by the
CC alternate allele present in mat1, either P (plus) in a h+ or M (minus)
CC in a h- cell. Mat2-P and mat3-M serve as donor of information that is
CC transposed to mat1 during a switch of mating type.
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DR EMBL; CU329671; CAD99125.1; -; Genomic_DNA.
DR PIR; S00571; S00571.
DR RefSeq; NP_001018808.1; NM_001021772.1.
DR RefSeq; NP_595874.1; NM_001021780.1.
DR AlphaFoldDB; P0CY15; -.
DR SMR; P0CY15; -.
DR BioGRID; 280337; 1.
DR IntAct; P0CY15; 1.
DR STRING; 4896.SPBC1711.01c.1; -.
DR PaxDb; P0CY15; -.
DR EnsemblFungi; SPBC1711.01c.1; SPBC1711.01c.1:pep; SPBC1711.01c.
DR EnsemblFungi; SPBC23G7.17c.1; SPBC23G7.17c.1:pep; SPBC23G7.17c.
DR EnsemblFungi; SPMTR.03.1; SPMTR.03.1:pep; SPMTR.03.
DR GeneID; 2539637; -.
DR GeneID; 3361261; -.
DR KEGG; spo:SPBC1711.01c; -.
DR KEGG; spo:SPBC23G7.17c; -.
DR PomBase; SPBC23G7.17c; mat1-Mi.
DR VEuPathDB; FungiDB:SPBC1711.01c; -.
DR VEuPathDB; FungiDB:SPBC23G7.17c; -.
DR VEuPathDB; FungiDB:SPMTR.03; -.
DR HOGENOM; CLU_3260800_0_0_1; -.
DR PRO; PR:P0CY15; -.
DR Proteomes; UP000002485; Chromosome II.
DR GO; GO:0000785; C:chromatin; IDA:PomBase.
DR GO; GO:0005737; C:cytoplasm; EXP:PomBase.
DR GO; GO:0005634; C:nucleus; EXP:PomBase.
DR GO; GO:0062071; C:Pi Mi complex; EXP:PomBase.
DR GO; GO:0007531; P:mating type determination; NAS:PomBase.
DR GO; GO:0140538; P:negative regulation of conjugation with zygote; IMP:PomBase.
DR GO; GO:0051446; P:positive regulation of meiotic cell cycle; IMP:PomBase.
DR GO; GO:0010673; P:positive regulation of transcription from RNA polymerase II promoter involved in meiotic cell cycle; IDA:PomBase.
DR GO; GO:0110044; P:regulation of cell cycle switching, mitotic to meiotic cell cycle; IDA:PomBase.
DR GO; GO:0110046; P:signal transduction involved in cell cycle switching, mitotic to meiotic cell cycle; IMP:PomBase.
PE 1: Evidence at protein level;
KW Cytoplasm; Nucleus; Reference proteome.
FT CHAIN 1..42
FT /note="Mating-type M-specific polypeptide Mi"
FT /id="PRO_0000410972"
SQ SEQUENCE 42 AA; 4858 MW; AAF0575237606622 CRC64;
MSAEDLFTIQ ILCDQIELKL ASIVINSNIK LQLKRKKKTQ QL
