MATPC_SCHKA
ID MATPC_SCHKA Reviewed; 118 AA.
AC Q6WRX9;
DT 31-AUG-2004, integrated into UniProtKB/Swiss-Prot.
DT 05-JUL-2004, sequence version 1.
DT 25-MAY-2022, entry version 46.
DE RecName: Full=Mating-type P-specific polypeptide Pc;
GN Name=matPc;
OS Schizosaccharomyces kambucha (Fission yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC Schizosaccharomyces.
OX NCBI_TaxID=204045;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=14618565; DOI=10.1002/yea.1042;
RA Singh G., Klar A.J.S.;
RT "DNA sequence of the mat2,3 region of Schizosaccharomyces kambucha shares
RT high homology with the corresponding sequence from Sz. pombe.";
RL Yeast 20:1273-1278(2003).
CC -!- FUNCTION: Mating type proteins are sequence specific DNA-binding
CC proteins that act as master switches in yeast differentiation by
CC controlling gene expression in a cell type-specific fashion. Required
CC for conjugation and efficient meiosis (By similarity). {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
CC -!- MISCELLANEOUS: There are three genetic loci for mating type genes in
CC fission yeast, mat1, mat2-P and mat3-M. Cell type is determined by the
CC alternate allele present in mat1, either P (plus) in a h+ or M (minus)
CC in a h- cell. Mat2-P and mat3-M serve as donor of information that is
CC transposed to mat1 during a switch of mating type (By similarity).
CC {ECO:0000250}.
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DR EMBL; AY271822; AAQ82719.1; -; Genomic_DNA.
DR AlphaFoldDB; Q6WRX9; -.
DR SMR; Q6WRX9; -.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR InterPro; IPR009071; HMG_box_dom.
DR InterPro; IPR036910; HMG_box_dom_sf.
DR SMART; SM00398; HMG; 1.
DR SUPFAM; SSF47095; SSF47095; 1.
PE 3: Inferred from homology;
KW DNA-binding; Nucleus; Transcription; Transcription regulation.
FT CHAIN 1..118
FT /note="Mating-type P-specific polypeptide Pc"
FT /id="PRO_0000048586"
FT DNA_BIND 29..97
FT /note="HMG box"
SQ SEQUENCE 118 AA; 13804 MW; 32F170E6678D53D7 CRC64;
MDPRLRAPIF LPILTPETLQ KKKQIKGNKT TIYKNGFMLF RSRLHKILNL SGDWAGASAK
CSIIWHTLPQ NVRLAWSQLA ELSHYQDVRK QIAKLERILY SKRLNGHNNY KLHISRVQ