ID   MATRX_BEFVB             Reviewed;         223 AA.
AC   Q9E785;
DT   11-SEP-2007, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2001, sequence version 1.
DT   29-SEP-2021, entry version 66.
DE   RecName: Full=Matrix protein;
GN   Name=M;
OS   Bovine ephemeral fever virus (strain BB7721) (BEFV).
OC   Viruses; Riboviria; Orthornavirae; Negarnaviricota; Haploviricotina;
OC   Monjiviricetes; Mononegavirales; Rhabdoviridae; Alpharhabdovirinae;
OC   Ephemerovirus.
OX   NCBI_TaxID=928297;
OH   NCBI_TaxID=9913; Bos taurus (Bovine).
OH   NCBI_TaxID=89462; Bubalus bubalis (Domestic water buffalo).
OH   NCBI_TaxID=58271; Culicoides.
OH   NCBI_TaxID=9970; Syncerus caffer (African buffalo).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC RNA].
RX   PubMed=11074128; DOI=10.1016/s0168-1702(00)00215-x;
RA   Dhillon J., Cowley J.A., Wang Y., Walker P.J.;
RT   "RNA polymerase (L) gene and genome terminal sequences of ephemeroviruses
RT   bovine ephemeral fever virus and Adelaide River virus indicate a close
RT   relationship to vesiculoviruses.";
RL   Virus Res. 70:87-95(2000).
CC   -!- FUNCTION: Plays a major role in assembly and budding of virion.
CC       Completely covers the ribonucleoprotein coil and keep it in condensed
CC       bullet-shaped form. Inhibits viral transcription and stimulates
CC       replication (By similarity). {ECO:0000250}.
CC   -!- SUBUNIT: Homomultimer. Interacts with nucleoprotein and with the
CC       cytoplasmic domain of glycoprotein (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Virion membrane; Peripheral membrane protein.
CC       Host endomembrane system {ECO:0000250}; Peripheral membrane protein
CC       {ECO:0000250}.
CC   -!- MISCELLANEOUS: Most abundant protein in the virion. {ECO:0000250}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AF234533; AAG10412.1; -; Genomic_RNA.
DR   RefSeq; NP_065401.1; NC_002526.1.
DR   PRIDE; Q9E785; -.
DR   GeneID; 911728; -.
DR   KEGG; vg:911728; -.
DR   Proteomes; UP000008588; Genome.
DR   GO; GO:0033645; C:host cell endomembrane system; IEA:UniProtKB-SubCell.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0019031; C:viral envelope; IEA:UniProtKB-KW.
DR   GO; GO:0055036; C:virion membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0039660; F:structural constituent of virion; IEA:UniProtKB-KW.
DR   InterPro; IPR009397; Vesiculo_matrix.
DR   Pfam; PF06326; Vesiculo_matrix; 1.
PE   3: Inferred from homology;
KW   Apoptosis; Host membrane; Membrane; Reference proteome;
KW   Viral envelope protein; Viral matrix protein; Virion.
FT   CHAIN           1..223
FT                   /note="Matrix protein"
FT                   /id="PRO_0000299245"
FT   REGION          1..23
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   223 AA;  25494 MW;  D14C2C60F1105CD4 CRC64;
     MLTLFKKGKP KGGSVDDRNS SYRESDPMLV WGTAPPAYLD VYHDERDKNE LQFNTKSYLI
     QANLEVISSK PIERTTEMLK VLDVMVDEYD GSYLSKALII TSYLTIGTHL RRMMSSVKNN
     HKYNNGFTEV IEFTGTAEIH PRDQEIKYNK YLMTSHMGEP VSISYQFSGK KSKRRGKNIL
     DAYNLELGNG SKPPDLKDLL ESYEINLCYN LKGEHGFTNL VKS