ID   MATRX_MEASA             Reviewed;         335 AA.
AC   P35976;
DT   01-JUN-1994, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-1994, sequence version 1.
DT   29-SEP-2021, entry version 61.
DE   RecName: Full=Matrix protein;
GN   Name=M;
OS   Measles virus (strain Edmonston-AIK-C vaccine) (MeV) (Subacute sclerose
OS   panencephalitis virus).
OC   Viruses; Riboviria; Orthornavirae; Negarnaviricota; Haploviricotina;
OC   Monjiviricetes; Mononegavirales; Paramyxoviridae; Orthoparamyxovirinae;
OC   Morbillivirus.
OX   NCBI_TaxID=36408;
OH   NCBI_TaxID=9606; Homo sapiens (Human).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC RNA].
RX   PubMed=8470368; DOI=10.1007/bf01702349;
RA   Mori T., Sasaki K., Hashimoto H., Makino S.;
RT   "Molecular cloning and complete nucleotide sequence of genomic RNA of the
RT   AIK-C strain of attenuated measles virus.";
RL   Virus Genes 7:67-81(1993).
CC   -!- FUNCTION: The M protein has a crucial role in virus assembly and
CC       interacts with the RNP complex as well as with the viral membrane.
CC   -!- SUBUNIT: Interacts with host ANP32B. {ECO:0000250|UniProtKB:Q9W850}.
CC   -!- SUBCELLULAR LOCATION: Virion {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the morbillivirus/respirovirus/rubulavirus M
CC       protein family. {ECO:0000305}.
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DR   EMBL; S58435; AAB26144.1; -; Genomic_RNA.
DR   PIR; D48556; D48556.
DR   SMR; P35976; -.
DR   TCDB; 9.A.73.4.2; the virus matrix protein (vmp) family.
DR   Proteomes; UP000007775; Genome.
DR   GO; GO:0019031; C:viral envelope; IEA:UniProtKB-KW.
DR   GO; GO:0039660; F:structural constituent of virion; IEA:UniProtKB-KW.
DR   GO; GO:0019064; P:fusion of virus membrane with host plasma membrane; IMP:CACAO.
DR   GO; GO:0019068; P:virion assembly; IEA:InterPro.
DR   Gene3D; 2.70.20.50; -; 1.
DR   Gene3D; 2.70.20.60; -; 1.
DR   InterPro; IPR000982; Matrix.
DR   InterPro; IPR042539; Matrix_C.
DR   InterPro; IPR042540; Matrix_N.
DR   Pfam; PF00661; Matrix; 1.
PE   3: Inferred from homology;
KW   Host-virus interaction; Viral envelope protein; Viral matrix protein;
KW   Virion.
FT   CHAIN           1..335
FT                   /note="Matrix protein"
FT                   /id="PRO_0000142750"
SQ   SEQUENCE   335 AA;  37681 MW;  FA6B243672215079 CRC64;
     MTEIYDFDKS AWDIKGSIAP IQPTTYSDGR LVPQVRVIDP GLGDRKDECF MYMSLLGVVE
     DSDPLGPPIG RAFGSLPLGV GRSTAKPEKL LKEATELDIV VRRTAGLNEK LVFYNNTPLT
     LLTPWRKVLT TGSVFNANQV CNAVNLIPLD TPQRFRVVYM SITRLSDNGY YTVPRRMLEF
     RSVNAVAFNL LVTLRIDKAI GPGKIIDNTE QLPEATFMVH IGNFRRKKSE VYSADYCKMK
     IEKMGLVFAL GGIGGTSLHI RSTGKMSKTL HAQLGFKKTL CYPLMDINED LNRLLWRSRC
     KIVRIQAVLQ PSVPQEFRIY DDVIINDDQG LFKVL