ID   MATRX_MEASB             Reviewed;         343 AA.
AC   P16628;
DT   01-AUG-1990, integrated into UniProtKB/Swiss-Prot.
DT   01-AUG-1990, sequence version 1.
DT   03-AUG-2022, entry version 59.
DE   RecName: Full=Matrix protein;
GN   Name=M;
OS   Measles virus (strain Biken) (MeV) (Subacute sclerosing panencephalitis
OS   virus (strain Biken)).
OC   Viruses; Riboviria; Orthornavirae; Negarnaviricota; Haploviricotina;
OC   Monjiviricetes; Mononegavirales; Paramyxoviridae; Orthoparamyxovirinae;
OC   Morbillivirus.
OX   NCBI_TaxID=351669;
OH   NCBI_TaxID=9606; Homo sapiens (Human).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC RNA].
RX   PubMed=2769235; DOI=10.1099/0022-1317-70-8-2191;
RA   Enami M., Sato T.A., Sugiura A.;
RT   "Matrix protein of cell-associated subacute sclerosing panencephalitis
RT   viruses.";
RL   J. Gen. Virol. 70:2191-2196(1989).
CC   -!- FUNCTION: The M protein has a crucial role in virus assembly and
CC       interacts with the RNP complex as well as with the viral membrane.
CC   -!- SUBUNIT: Interacts with host ANP32B. {ECO:0000250|UniProtKB:Q9W850}.
CC   -!- SUBCELLULAR LOCATION: Virion {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the morbillivirus/respirovirus/rubulavirus M
CC       protein family. {ECO:0000305}.
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DR   EMBL; D00495; BAA00381.1; -; Genomic_RNA.
DR   SMR; P16628; -.
DR   PRIDE; P16628; -.
DR   GO; GO:0019031; C:viral envelope; IEA:UniProtKB-KW.
DR   GO; GO:0039660; F:structural constituent of virion; IEA:UniProtKB-KW.
DR   GO; GO:0019068; P:virion assembly; IEA:InterPro.
DR   Gene3D; 2.70.20.50; -; 1.
DR   Gene3D; 2.70.20.60; -; 1.
DR   InterPro; IPR000982; Matrix.
DR   InterPro; IPR042539; Matrix_C.
DR   InterPro; IPR042540; Matrix_N.
DR   Pfam; PF00661; Matrix; 1.
PE   3: Inferred from homology;
KW   Host-virus interaction; Viral envelope protein; Viral matrix protein;
KW   Virion.
FT   CHAIN           1..343
FT                   /note="Matrix protein"
FT                   /id="PRO_0000142751"
SQ   SEQUENCE   343 AA;  38173 MW;  24D090886E24FB78 CRC64;
     MTEIYDFDKS AWDIKGSIAP TQPTTHSEGR LVPQVRVIDP GPGDRKDECL MYMSLLGVVE
     DSDPLGPPIG RAFGSPPLGV GRSTAKPEEL LKEATELDIV VRRTAGLNEK LVFYNNTPLT
     LPTPWRKVPT TGSVFNANQV CNAVNLTPLD TPQRFRVVYT SITRLSDNGH YTVPRRMLEF
     RSVNAVAFNL LATLRIDKAI GHGKIIDNAE QLPEATFMVH IGNFRRKKSE VYSADHCKME
     IEKMGLVFAL GGIGGTSPHI RSTGKMSKTL HAQLGFKKTL CYPLMDINED LNRLLWRSRC
     KIARIQAVLQ PSVPQEFRIY DDVIINDDQG LFKALQTVVP SNA