ID   MATRX_MEASC             Reviewed;         335 AA.
AC   Q9W850;
DT   15-JUN-2010, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1999, sequence version 1.
DT   07-APR-2021, entry version 63.
DE   RecName: Full=Matrix protein;
GN   Name=M;
OS   Measles virus (strain Ichinose-B95a) (MeV) (Subacute sclerose
OS   panencephalitis virus).
OC   Viruses; Riboviria; Orthornavirae; Negarnaviricota; Haploviricotina;
OC   Monjiviricetes; Mononegavirales; Paramyxoviridae; Orthoparamyxovirinae;
OC   Morbillivirus.
OX   NCBI_TaxID=645098;
OH   NCBI_TaxID=9606; Homo sapiens (Human).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC RNA].
RX   PubMed=10949953; DOI=10.1023/a:1008196729676;
RA   Takeuchi K., Miyajima N., Kobune F., Tashiro M.;
RT   "Comparative nucleotide sequence analyses of the entire genomes of B95a
RT   cell-isolated and vero cell-isolated measles viruses from the same
RT   patient.";
RL   Virus Genes 20:253-257(2000).
RN   [2]
RP   INTERACTION WITH HOST ANP32B.
RX   PubMed=31793855; DOI=10.1099/jgv.0.001362;
RA   Guenther M., Bauer A., Mueller M., Zaeck L., Finke S.;
RT   "Interaction of host cellular factor ANP32B with matrix proteins of
RT   different paramyxoviruses.";
RL   J. Gen. Virol. 101:44-58(2020).
CC   -!- FUNCTION: The M protein has a crucial role in virus assembly and
CC       interacts with the RNP complex as well as with the viral membrane.
CC       {ECO:0000250}.
CC   -!- SUBUNIT: Interacts with host ANP32B. {ECO:0000269|PubMed:31793855}.
CC   -!- SUBCELLULAR LOCATION: Virion {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the morbillivirus/respirovirus/rubulavirus M
CC       protein family. {ECO:0000305}.
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DR   EMBL; AB016162; BAA34980.1; -; Genomic_RNA.
DR   PIR; PQ0375; PQ0375.
DR   PIR; PQ0379; PQ0379.
DR   PIR; PQ0383; PQ0383.
DR   PIR; PQ0387; PQ0387.
DR   RefSeq; NP_056921.1; NC_001498.1.
DR   SMR; Q9W850; -.
DR   GeneID; 1489803; -.
DR   KEGG; vg:1489803; -.
DR   Proteomes; UP000008699; Genome.
DR   GO; GO:0019031; C:viral envelope; IEA:UniProtKB-KW.
DR   GO; GO:0039660; F:structural constituent of virion; IEA:UniProtKB-KW.
DR   GO; GO:0019068; P:virion assembly; IEA:InterPro.
DR   Gene3D; 2.70.20.50; -; 1.
DR   Gene3D; 2.70.20.60; -; 1.
DR   InterPro; IPR000982; Matrix.
DR   InterPro; IPR042539; Matrix_C.
DR   InterPro; IPR042540; Matrix_N.
DR   Pfam; PF00661; Matrix; 1.
PE   1: Evidence at protein level;
KW   Host-virus interaction; Reference proteome; Viral envelope protein;
KW   Viral matrix protein; Virion.
FT   CHAIN           1..335
FT                   /note="Matrix protein"
FT                   /id="PRO_0000394719"
SQ   SEQUENCE   335 AA;  37712 MW;  471E73537F58BC1D CRC64;
     MTEIYDFDKS AWDIKGSIAP IQPTTYSDGR LVPQVRVIDP GLGDRKDECF MYMFLLGVVE
     DSDPLGPPIG RAFGSLPLGV GRSTAKPEEL LKEATELDIV VRRTAGLNEK LVFYNNTPLT
     LLTPWRKVLT TGSVFNANQV CNAVNLIPLD TPQRFRVVYM SITRLSDNGY YTVPRRMLEF
     RSVNAVAFNL LVTLRIDKAI GPGKIIDNAE QLPEATFMVH IGNFRRKKSE VYSADYCKMK
     IEKMGLVFAL GGIGGTSLHI RSTGKMSKTL HAQLGFKKTL CYPLMDINED LNRLLWRSRC
     KIVRIQAVLQ PSVPQEFRIY DDVIINDDQG LFKVL