ID   MATRX_MEASH             Reviewed;         335 AA.
AC   P18611;
DT   01-NOV-1990, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1990, sequence version 1.
DT   07-APR-2021, entry version 56.
DE   RecName: Full=Matrix protein;
GN   Name=M;
OS   Measles virus (strain Halle) (MeV) (Subacute sclerose panencephalitis
OS   virus).
OC   Viruses; Riboviria; Orthornavirae; Negarnaviricota; Haploviricotina;
OC   Monjiviricetes; Mononegavirales; Paramyxoviridae; Orthoparamyxovirinae;
OC   Morbillivirus.
OX   NCBI_TaxID=11236;
OH   NCBI_TaxID=9606; Homo sapiens (Human).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC RNA].
RX   PubMed=2402450; DOI=10.1093/nar/18.17.5283;
RA   Buckland R., Cheynet V., Beauverger P., Wild F.;
RT   "Cloning of the matrix gene of measles virus (Halle strain).";
RL   Nucleic Acids Res. 18:5283-5283(1990).
CC   -!- FUNCTION: The M protein has a crucial role in virus assembly and
CC       interacts with the RNP complex as well as with the viral membrane.
CC   -!- SUBUNIT: Interacts with host ANP32B. {ECO:0000250|UniProtKB:Q9W850}.
CC   -!- SUBCELLULAR LOCATION: Virion {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the morbillivirus/respirovirus/rubulavirus M
CC       protein family. {ECO:0000305}.
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DR   EMBL; X54068; CAA37999.1; -; Genomic_RNA.
DR   PIR; S11227; S11227.
DR   SMR; P18611; -.
DR   GO; GO:0019031; C:viral envelope; IEA:UniProtKB-KW.
DR   GO; GO:0039660; F:structural constituent of virion; IEA:UniProtKB-KW.
DR   GO; GO:0019068; P:virion assembly; IEA:InterPro.
DR   Gene3D; 2.70.20.50; -; 1.
DR   Gene3D; 2.70.20.60; -; 1.
DR   InterPro; IPR000982; Matrix.
DR   InterPro; IPR042539; Matrix_C.
DR   InterPro; IPR042540; Matrix_N.
DR   Pfam; PF00661; Matrix; 1.
PE   3: Inferred from homology;
KW   Host-virus interaction; Viral envelope protein; Viral matrix protein;
KW   Virion.
FT   CHAIN           1..335
FT                   /note="Matrix protein"
FT                   /id="PRO_0000142753"
SQ   SEQUENCE   335 AA;  37691 MW;  1C427F9B8D2CF872 CRC64;
     MTEIYDFDKS AWDIKGPIAP IQPTTYSDGR LVPQVRVIDP GLGDRKDECS MYMFLLGVVE
     DSDPLGPPIG RAFGSLPLGV GRSTAKPEKL LKEATELDIV VRRTAGLNEK LVFYNNTPLT
     LLTPWRKVLT TGSVFNANQV CNAVNLIPLD TPQRFRVVYM SITRLSDNGY YTVPRRMLEF
     RSVNAVAFNL LVTLRIDKAI GPGKIIDNTE QLPEATFMVH IGNFRRKKSE VYSADYCKMK
     IEKMGLVFAL GGIGGTSLHI RSTGKMSKTL HAQLGFKKTL CYPLMDINED LNRLLWRSRC
     KIVRIQAVLQ PSVPQEFRIY DDVIINDDQG LFKVL