ID   MATRX_MEASI             Reviewed;         335 AA.
AC   P26034;
DT   01-MAY-1992, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-1992, sequence version 1.
DT   07-APR-2021, entry version 58.
DE   RecName: Full=Matrix protein;
GN   Name=M;
OS   Measles virus (strain IP-3-Ca) (MeV) (Subacute sclerose panencephalitis
OS   virus).
OC   Viruses; Riboviria; Orthornavirae; Negarnaviricota; Haploviricotina;
OC   Monjiviricetes; Mononegavirales; Paramyxoviridae; Orthoparamyxovirinae;
OC   Morbillivirus.
OX   NCBI_TaxID=11237;
OH   NCBI_TaxID=9606; Homo sapiens (Human).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC RNA].
RX   PubMed=1585658; DOI=10.1016/0042-6822(92)90552-z;
RA   Schmid A., Spielhofer P., Cattaneo R., Baczko K., Ter Meulen V.,
RA   Billeter M.A.;
RT   "Subacute sclerosing panencephalitis is typically characterized by
RT   alterations in the fusion protein cytoplasmic domain of the persisting
RT   measles virus.";
RL   Virology 188:910-915(1992).
CC   -!- FUNCTION: The M protein has a crucial role in virus assembly and
CC       interacts with the RNP complex as well as with the viral membrane.
CC   -!- SUBUNIT: Interacts with host ANP32B. {ECO:0000250|UniProtKB:Q9W850}.
CC   -!- SUBCELLULAR LOCATION: Virion {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the morbillivirus/respirovirus/rubulavirus M
CC       protein family. {ECO:0000305}.
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DR   EMBL; X16566; CAA34566.1; -; Genomic_RNA.
DR   SMR; P26034; -.
DR   GO; GO:0019031; C:viral envelope; IEA:UniProtKB-KW.
DR   GO; GO:0039660; F:structural constituent of virion; IEA:UniProtKB-KW.
DR   GO; GO:0019068; P:virion assembly; IEA:InterPro.
DR   Gene3D; 2.70.20.50; -; 1.
DR   Gene3D; 2.70.20.60; -; 1.
DR   InterPro; IPR000982; Matrix.
DR   InterPro; IPR042539; Matrix_C.
DR   InterPro; IPR042540; Matrix_N.
DR   Pfam; PF00661; Matrix; 1.
PE   3: Inferred from homology;
KW   Host-virus interaction; Viral envelope protein; Viral matrix protein;
KW   Virion.
FT   CHAIN           1..335
FT                   /note="Matrix protein"
FT                   /id="PRO_0000142754"
SQ   SEQUENCE   335 AA;  37761 MW;  09416CD4D714F2AD CRC64;
     MTEIHDFDKS EWDIKGSIAP IQPTTYSDGR LVPQVRVTDP GLGDRKDECF MYMFLLGVVE
     DSDPLGPPIG RAFGSLPLGV GRSTAKPEEL LKEATELDIV VRRIAGLNEK LVFYNNPPLT
     LLTPWRKVLT TGSVFNANQV CNAVNLIPLD TPQRFRVVYM SITRLSDNGY YTVPRRMLEF
     KSVNAVAFKL LVTLRIHKAI GPGKIIDNAE QLPEATFMVH IGNFRRKKSE VYSADYCKMK
     IEKMGLVFAL GGIGGTSLHI RSTGKMNKTL HAQLGFKKTL CYPLMDINED PNRLLWRSRC
     KTIRIQAVLQ PSVPQEFRIY DDVIINDDQG LFKVL