ID   MATRX_MEASU             Reviewed;         335 AA.
AC   P13844;
DT   01-JAN-1990, integrated into UniProtKB/Swiss-Prot.
DT   01-JAN-1990, sequence version 1.
DT   07-APR-2021, entry version 57.
DE   RecName: Full=Matrix protein;
GN   Name=M;
OS   Measles virus (strain Hu2) (MeV) (Subacute sclerose panencephalitis virus).
OC   Viruses; Riboviria; Orthornavirae; Negarnaviricota; Haploviricotina;
OC   Monjiviricetes; Mononegavirales; Paramyxoviridae; Orthoparamyxovirinae;
OC   Morbillivirus.
OX   NCBI_TaxID=11238;
OH   NCBI_TaxID=9606; Homo sapiens (Human).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC RNA].
RX   PubMed=3411300; DOI=10.1099/0022-1317-69-9-2407;
RA   Curran M.D., Rima B.K.;
RT   "Nucleotide sequence of the gene encoding the matrix protein of a recent
RT   measles virus isolate.";
RL   J. Gen. Virol. 69:2407-2411(1988).
CC   -!- FUNCTION: The M protein has a crucial role in virus assembly and
CC       interacts with the RNP complex as well as with the viral membrane.
CC   -!- SUBUNIT: Interacts with host ANP32B. {ECO:0000250|UniProtKB:Q9W850}.
CC   -!- SUBCELLULAR LOCATION: Virion {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the morbillivirus/respirovirus/rubulavirus M
CC       protein family. {ECO:0000305}.
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DR   EMBL; D00338; BAA00242.1; -; Genomic_RNA.
DR   PIR; A31039; MFNZMH.
DR   SMR; P13844; -.
DR   GO; GO:0019031; C:viral envelope; IEA:UniProtKB-KW.
DR   GO; GO:0039660; F:structural constituent of virion; IEA:UniProtKB-KW.
DR   GO; GO:0019068; P:virion assembly; IEA:InterPro.
DR   Gene3D; 2.70.20.50; -; 1.
DR   Gene3D; 2.70.20.60; -; 1.
DR   InterPro; IPR000982; Matrix.
DR   InterPro; IPR042539; Matrix_C.
DR   InterPro; IPR042540; Matrix_N.
DR   Pfam; PF00661; Matrix; 1.
PE   3: Inferred from homology;
KW   Host-virus interaction; Viral envelope protein; Viral matrix protein;
KW   Virion.
FT   CHAIN           1..335
FT                   /note="Matrix protein"
FT                   /id="PRO_0000142755"
SQ   SEQUENCE   335 AA;  37674 MW;  CBD3E83F8A1BB56D CRC64;
     MTEIYDFDKS AWDIKGSIAP IQPTTYSDGR LVPQVRVIDP GLGDRKDECF MYMFLLGVVE
     DSDSLGPPIG RAFGSLPLGV GRSTAKPEEL LKEATELDIV VRRTAGLNEK LVFYNNTPLT
     LLTPWRKVLT TGSVFNANQV CNAVNLIPLD TPQRFRVVYM SITRLSDNGY YTVPRRMLEF
     RSVNAVAFNL LVTLRIDKAI GPGKIIDNTE QLPEATFMVH IGNFRRKKSE VYSADYCKMK
     IEKMGLVFAL GGIGGTSLHI RSTGKMSKTL HAQLGFKKTL CYPLMGINED LNRLLWRSRC
     KIVRIQAVLQ PSVPQEFRIY DDVIINDDQG LFKVL