ID   MATRX_NDVB1             Reviewed;         364 AA.
AC   Q9DLD5;
DT   19-JAN-2010, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2001, sequence version 1.
DT   07-APR-2021, entry version 52.
DE   RecName: Full=Matrix protein;
GN   Name=M;
OS   Newcastle disease virus (strain Chicken/United States/B1/48) (NDV).
OC   Viruses; Riboviria; Orthornavirae; Negarnaviricota; Haploviricotina;
OC   Monjiviricetes; Mononegavirales; Paramyxoviridae; Avulavirinae;
OC   Orthoavulavirus; Avian orthoavulavirus 1.
OX   NCBI_TaxID=652953;
OH   NCBI_TaxID=9031; Gallus gallus (Chicken).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC RNA].
RA   Sellers H.S., Seal B.S.;
RT   "Complete sequence for the B1 strain of Newcastle disease virus.";
RL   Submitted (SEP-2000) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: The M protein has a crucial role in virus assembly and
CC       interacts with the RNP complex as well as with the viral membrane.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Virion {ECO:0000305}.
CC   -!- DOMAIN: Late-budding domains (L domains) are short sequence motifs
CC       essential for viral particle budding. They recruit proteins of the host
CC       ESCRT machinery (Endosomal Sorting Complex Required for Transport) or
CC       ESCRT-associated proteins. The matrix protein contains one L domain: a
CC       FPIV motif (By similarity). {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the morbillivirus/respirovirus/rubulavirus M
CC       protein family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AF309418; AAG36981.1; -; Genomic_RNA.
DR   RefSeq; NP_071468.1; NC_002617.1.
DR   SMR; Q9DLD5; -.
DR   Proteomes; UP000002328; Genome.
DR   GO; GO:0019031; C:viral envelope; IEA:UniProtKB-KW.
DR   GO; GO:0039660; F:structural constituent of virion; IEA:UniProtKB-KW.
DR   GO; GO:0039702; P:viral budding via host ESCRT complex; IEA:UniProtKB-KW.
DR   Gene3D; 2.70.20.50; -; 1.
DR   Gene3D; 2.70.20.60; -; 1.
DR   InterPro; IPR000982; Matrix.
DR   InterPro; IPR042539; Matrix_C.
DR   InterPro; IPR042540; Matrix_N.
DR   Pfam; PF00661; Matrix; 1.
PE   3: Inferred from homology;
KW   Host-virus interaction; Reference proteome; Viral budding;
KW   Viral budding via the host ESCRT complexes; Viral envelope protein;
KW   Viral matrix protein; Viral release from host cell; Virion.
FT   CHAIN           1..364
FT                   /note="Matrix protein"
FT                   /id="PRO_0000390628"
FT   MOTIF           23..26
FT                   /note="FPIV motif"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   364 AA;  39610 MW;  BDF1605F27ABB5CF CRC64;
     MDSSRTIGLY FDSAHSSSNL LAFPIVLQDT GDGKKQIAPQ YRIQRLDLWT DSKEDSVFIT
     TYGFIFQVGN EEATVGIIDD KPKRELLSAA MLCLGSVPNT GDLIELARAC LTMMVTCKKS
     ATNTERMVFS VVQAPQVLQS CRVVANKYSS VNAVKHVKAP EKIPGSGTLE YKVNFVSLTV
     VPKKDVYKIP AAVLKISGSS LYNLALNVTI NVEVDPRSPL VKSLSKSDSG YYANLFLHIG
     LMTTVDRKGK KVTFDKLEKK IRSLDLSVGL SDVLGPSVLV KARGARTKLL APFFSSSGTA
     CYPIANASPQ VAKILWSQTA CLRSVKIIIQ AGTQRAVAVT ADHEVTSTKL EKGHTLAKYN
     PFKK