ID   MATRX_PI1HC             Reviewed;         348 AA.
AC   Q01427;
DT   01-JUL-1993, integrated into UniProtKB/Swiss-Prot.
DT   01-JUL-1993, sequence version 1.
DT   07-OCT-2020, entry version 54.
DE   RecName: Full=Matrix protein;
GN   Name=M;
OS   Human parainfluenza 1 virus (strain C39) (HPIV-1).
OC   Viruses; Riboviria; Orthornavirae; Negarnaviricota; Haploviricotina;
OC   Monjiviricetes; Mononegavirales; Paramyxoviridae; Orthoparamyxovirinae;
OC   Respirovirus.
OX   NCBI_TaxID=11210;
OH   NCBI_TaxID=9606; Homo sapiens (Human).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC RNA].
RX   PubMed=1333129; DOI=10.1016/0042-6822(92)90270-y;
RA   Power U.F., Ryan K.W., Portner A.;
RT   "Sequence characterization and expression of the matrix protein gene of
RT   human parainfluenza virus type 1.";
RL   Virology 191:947-952(1992).
CC   -!- FUNCTION: The M protein has a crucial role in virus assembly and
CC       interacts with the RNP complex as well as with the viral membrane.
CC   -!- SUBCELLULAR LOCATION: Virion {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the morbillivirus/respirovirus/rubulavirus M
CC       protein family. {ECO:0000305}.
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DR   EMBL; M80818; AAA46861.1; -; Genomic_RNA.
DR   PIR; A44218; MFNZC3.
DR   SMR; Q01427; -.
DR   GO; GO:0019031; C:viral envelope; IEA:UniProtKB-KW.
DR   GO; GO:0039660; F:structural constituent of virion; IEA:UniProtKB-KW.
DR   GO; GO:0019068; P:virion assembly; IEA:InterPro.
DR   Gene3D; 2.70.20.50; -; 1.
DR   Gene3D; 2.70.20.60; -; 1.
DR   InterPro; IPR000982; Matrix.
DR   InterPro; IPR042539; Matrix_C.
DR   InterPro; IPR042540; Matrix_N.
DR   Pfam; PF00661; Matrix; 1.
PE   3: Inferred from homology;
KW   Disulfide bond; Viral envelope protein; Viral matrix protein; Virion.
FT   CHAIN           1..348
FT                   /note="Matrix protein"
FT                   /id="PRO_0000142763"
FT   DISULFID        251..295
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   348 AA;  38401 MW;  EE10B75712D3AE4B CRC64;
     MAETYRFPRF SHEENGTVEP LPLKTGPDKK AIPHIRIVKV GDPPKHGVRY LDVLLLGFFE
     TPKQGPLSGS ISDLTESTSY SICGSGSLPI GIAKYYGTDQ ELLKACIDLK ITVRRTVRSG
     EMIVYMVDSI HAPLLPWSGR LRQGMIYNAN KVALAPQCLP VDKDIRFRVV FVNGTSLGTI
     TIAKVPKTLA DLALPNSISV NLLVTLKAGV STEQKGILPV LDDDGEKKLN FMVHLGIIRR
     KVGKIYSVEY CKNKIEKMKL IFSLGLVGGI SFHVHATGTL SKTLMSQLAW KKAVCYPLMD
     VNPHMNLVIW AASVEITSVD AVFQPAIPKE FRYYPNVVAK SIGKIRKI