ID   ARGP_AERSA              Reviewed;         299 AA.
AC   P70773;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1997, sequence version 1.
DT   25-MAY-2022, entry version 86.
DE   RecName: Full=HTH-type transcriptional regulator ArgP {ECO:0000255|HAMAP-Rule:MF_00513};
GN   Name=argP {ECO:0000255|HAMAP-Rule:MF_00513}; Synonyms=iciA;
OS   Aeromonas salmonicida.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Aeromonadales;
OC   Aeromonadaceae; Aeromonas.
OX   NCBI_TaxID=645;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=ATCC 33658 / DSM 19634 / JCM 7874 / NCIMB 1102 / NCTC 12959;
RX   PubMed=9286976; DOI=10.1128/jb.179.17.5271-5281.1997;
RA   Swift S., Karlyshev A.V., Fish L., Durant E.L., Winson M.K., Chhabra S.R.,
RA   Williams P., Macintyre S., Stewart G.S.A.B.;
RT   "Quorum sensing in Aeromonas hydrophila and Aeromonas salmonicida:
RT   identification of the LuxRI homologs AhyRI and AsaRI and their cognate N-
RT   acylhomoserine lactone signal molecules.";
RL   J. Bacteriol. 179:5271-5281(1997).
CC   -!- FUNCTION: Controls the transcription of genes involved in arginine and
CC       lysine metabolism. {ECO:0000255|HAMAP-Rule:MF_00513}.
CC   -!- SUBUNIT: Homodimer. {ECO:0000255|HAMAP-Rule:MF_00513}.
CC   -!- SIMILARITY: Belongs to the LysR transcriptional regulatory family.
CC       {ECO:0000305}.
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DR   EMBL; U65741; AAB70016.1; -; Genomic_DNA.
DR   RefSeq; WP_005315947.1; NZ_UFSF01000001.1.
DR   AlphaFoldDB; P70773; -.
DR   SMR; P70773; -.
DR   STRING; 1233098.GCA_000315855_00758; -.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:UniProtKB-UniRule.
DR   Gene3D; 1.10.10.10; -; 1.
DR   HAMAP; MF_00513; HTH_type_ArgP; 1.
DR   InterPro; IPR017685; ArgP.
DR   InterPro; IPR023490; ArgP_Gammaproteobact.
DR   InterPro; IPR005119; LysR_subst-bd.
DR   InterPro; IPR000847; Tscrpt_reg_HTH_LysR.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   Pfam; PF00126; HTH_1; 1.
DR   Pfam; PF03466; LysR_substrate; 1.
DR   PRINTS; PR00039; HTHLYSR.
DR   SUPFAM; SSF46785; SSF46785; 1.
DR   TIGRFAMs; TIGR03298; argP; 1.
DR   PROSITE; PS50931; HTH_LYSR; 1.
PE   3: Inferred from homology;
KW   DNA-binding; Transcription; Transcription regulation.
FT   CHAIN           1..299
FT                   /note="HTH-type transcriptional regulator ArgP"
FT                   /id="PRO_0000105640"
FT   DOMAIN          4..60
FT                   /note="HTH lysR-type"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00513"
FT   DNA_BIND        21..40
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00513"
SQ   SEQUENCE   299 AA;  33411 MW;  5EEBECA44CC5A68D CRC64;
     MKALDYKLLL ALDAVMQEQN FERAAQRLHI TQSAISQRIK QLEQQFAEPL LIRSQPLQAT
     PLGQKLLAHY RQVRQLELEL AGEIAPDEPQ APIRVSIAVN ADSLATWFLP ALAPLLEQHP
     IELNLLVDDE CRTLDRVREG QAFGAVSLHG QPLAGCCVDE LGEMRYLLTA SPAFVARHFP
     AGLTPAALAK TPAVAFDQRD DMHVSFMARH FGLEPGGYPC HTVRSSEAFV AMAEQGLAYC
     LIPELQIRQQ LAQGILLDLS PSHHLIEPLY WHRWVLERGL HKQISQRLIS EGRRALQPG