ARGP_CROS8
ID ARGP_CROS8 Reviewed; 297 AA.
AC A7MR91;
DT 05-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT 02-OCT-2007, sequence version 1.
DT 03-AUG-2022, entry version 83.
DE RecName: Full=HTH-type transcriptional regulator ArgP {ECO:0000255|HAMAP-Rule:MF_00513};
GN Name=argP {ECO:0000255|HAMAP-Rule:MF_00513}; Synonyms=iciA;
GN OrderedLocusNames=ESA_00414;
OS Cronobacter sakazakii (strain ATCC BAA-894) (Enterobacter sakazakii).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Cronobacter.
OX NCBI_TaxID=290339;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-894;
RX PubMed=20221447; DOI=10.1371/journal.pone.0009556;
RA Kucerova E., Clifton S.W., Xia X.Q., Long F., Porwollik S., Fulton L.,
RA Fronick C., Minx P., Kyung K., Warren W., Fulton R., Feng D., Wollam A.,
RA Shah N., Bhonagiri V., Nash W.E., Hallsworth-Pepin K., Wilson R.K.,
RA McClelland M., Forsythe S.J.;
RT "Genome sequence of Cronobacter sakazakii BAA-894 and comparative genomic
RT hybridization analysis with other Cronobacter species.";
RL PLoS ONE 5:E9556-E9556(2010).
CC -!- FUNCTION: Controls the transcription of genes involved in arginine and
CC lysine metabolism. {ECO:0000255|HAMAP-Rule:MF_00513}.
CC -!- SUBUNIT: Homodimer. {ECO:0000255|HAMAP-Rule:MF_00513}.
CC -!- SIMILARITY: Belongs to the LysR transcriptional regulatory family.
CC {ECO:0000305}.
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DR EMBL; CP000783; ABU75712.1; -; Genomic_DNA.
DR RefSeq; WP_004385653.1; NC_009778.1.
DR AlphaFoldDB; A7MR91; -.
DR SMR; A7MR91; -.
DR EnsemblBacteria; ABU75712; ABU75712; ESA_00414.
DR GeneID; 56733371; -.
DR KEGG; esa:ESA_00414; -.
DR HOGENOM; CLU_063829_0_0_6; -.
DR OMA; QQWKLDS; -.
DR OrthoDB; 951478at2; -.
DR Proteomes; UP000000260; Chromosome.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:UniProtKB-UniRule.
DR Gene3D; 1.10.10.10; -; 1.
DR HAMAP; MF_00513; HTH_type_ArgP; 1.
DR InterPro; IPR017685; ArgP.
DR InterPro; IPR023490; ArgP_Gammaproteobact.
DR InterPro; IPR005119; LysR_subst-bd.
DR InterPro; IPR000847; Tscrpt_reg_HTH_LysR.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR Pfam; PF00126; HTH_1; 1.
DR Pfam; PF03466; LysR_substrate; 1.
DR PRINTS; PR00039; HTHLYSR.
DR SUPFAM; SSF46785; SSF46785; 1.
DR TIGRFAMs; TIGR03298; argP; 1.
DR PROSITE; PS50931; HTH_LYSR; 1.
PE 3: Inferred from homology;
KW DNA-binding; Transcription; Transcription regulation.
FT CHAIN 1..297
FT /note="HTH-type transcriptional regulator ArgP"
FT /id="PRO_1000060878"
FT DOMAIN 4..60
FT /note="HTH lysR-type"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00513"
FT DNA_BIND 21..40
FT /note="H-T-H motif"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00513"
SQ SEQUENCE 297 AA; 33429 MW; CAA4036FF581AA6F CRC64;
MKRPDYRTLQ ALDAVIRERG FERAAQKLCI TQSAVSQRIK QLENTFGQPL LVRTVPPRPT
EQGQKLLALL RQVELLEEEW LGDEQTGSTP LLLSLAVNAD SLATWLLPAL APVLADSPVR
LNLQVEDETR TQERLRRGEV VGAVSIQPQA LPSCLVDQLG ALDYLFVASK PFADRYFPNG
VTRASLLKAP AVAFDHLDDM HQAFLQQNFD LPPGSVPCHI VNSSEAFVQL ARQGTTCCMI
PHLQIEKELQ SGELIDLTPG LYQRRMLFWH RFAPESRMMR KVTDALLEYG HKVLRQD