ID   MATRX_TUPVT             Reviewed;         200 AA.
AC   Q4VKV5;
DT   04-MAR-2015, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2005, sequence version 1.
DT   29-SEP-2021, entry version 35.
DE   RecName: Full=Matrix protein;
GN   Name=M;
OS   Tupaia virus (isolate Tupaia/Thailand/-/1986) (TUPV).
OC   Viruses; Riboviria; Orthornavirae; Negarnaviricota; Haploviricotina;
OC   Monjiviricetes; Mononegavirales; Rhabdoviridae; Alpharhabdovirinae;
OC   Tupavirus.
OX   NCBI_TaxID=1560034;
OH   NCBI_TaxID=9394; Tupaia.
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC RNA].
RX   PubMed=15890917; DOI=10.1128/jvi.79.11.6781-6790.2005;
RA   Springfeld C., Darai G., Cattaneo R.;
RT   "Characterization of the Tupaia rhabdovirus genome reveals a long open
RT   reading frame overlapping with P and a novel gene encoding a small
RT   hydrophobic protein.";
RL   J. Virol. 79:6781-6790(2005).
CC   -!- FUNCTION: Plays a major role in assembly and budding of virion, by
CC       recruiting cellular partners of the ESCRT complexes that play a key
CC       role in releasing the budding particle from the host membrane.
CC       Condensates the ribonucleocapsid core during virus assembly.
CC       {ECO:0000250|UniProtKB:P03519}.
CC   -!- SUBUNIT: Homomultimer. Interacts with viral nucleocapsid.
CC       {ECO:0000250|UniProtKB:P03519}.
CC   -!- SUBCELLULAR LOCATION: Virion membrane {ECO:0000250|UniProtKB:P03519};
CC       Peripheral membrane protein {ECO:0000250|UniProtKB:P03519}. Host
CC       endomembrane system {ECO:0000250|UniProtKB:P03519}; Peripheral membrane
CC       protein {ECO:0000250|UniProtKB:P03519}. Host nucleus membrane
CC       {ECO:0000250|UniProtKB:P03519}; Peripheral membrane protein
CC       {ECO:0000250|UniProtKB:P03519}.
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DR   EMBL; AY840978; AAX47599.1; -; Genomic_RNA.
DR   RefSeq; YP_238531.1; NC_007020.1.
DR   GeneID; 3416612; -.
DR   KEGG; vg:3416612; -.
DR   Proteomes; UP000029771; Genome.
DR   GO; GO:0044200; C:host cell nuclear membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0055036; C:virion membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0039660; F:structural constituent of virion; IEA:UniProtKB-KW.
DR   GO; GO:0039702; P:viral budding via host ESCRT complex; IEA:UniProtKB-KW.
PE   3: Inferred from homology;
KW   Host membrane; Host nucleus; Host-virus interaction; Membrane;
KW   Reference proteome; Viral budding;
KW   Viral budding via the host ESCRT complexes; Viral matrix protein;
KW   Viral release from host cell; Virion.
FT   CHAIN           1..200
FT                   /note="Matrix protein"
FT                   /id="PRO_0000432062"
SQ   SEQUENCE   200 AA;  22433 MW;  E09BAE57968496DA CRC64;
     MLRWFSFGSN EGSEVAGNGW SVKPIGNMSI KKDDPVGFPQ GYQCLLKVII QLEKKDPTKS
     DVSELIAGWV KRYSGPHLLE RLIKALIILT VPKLSRENID NHVKLGGLFE GQVTFHFSSR
     DLIPTKYLSY ATSIRTTVKG IYSYLSIEAE LNPSSHQGTS VAKLLRASDV AKYYDNTLQS
     IFSQFEIKNV TITDDQIIFN