ID   MAUD_METEA              Reviewed;         205 AA.
AC   Q49126; C5ATK6;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   03-AUG-2022, entry version 119.
DE   RecName: Full=Methylamine utilization protein MauD;
GN   Name=mauD; OrderedLocusNames=MexAM1_META1p2772;
OS   Methylorubrum extorquens (strain ATCC 14718 / DSM 1338 / JCM 2805 / NCIMB
OS   9133 / AM1) (Methylobacterium extorquens).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Hyphomicrobiales;
OC   Methylobacteriaceae; Methylorubrum.
OX   NCBI_TaxID=272630;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=8021187; DOI=10.1128/jb.176.13.4052-4065.1994;
RA   Chistoserdov A.Y., Chistoserdova L.V., McIntire W.S., Lidstrom M.E.;
RT   "Genetic organization of the mau gene cluster in Methylobacterium
RT   extorquens AM1: complete nucleotide sequence and generation and
RT   characteristics of mau mutants.";
RL   J. Bacteriol. 176:4052-4065(1994).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 14718 / DSM 1338 / JCM 2805 / NCIMB 9133 / AM1;
RX   PubMed=19440302; DOI=10.1371/journal.pone.0005584;
RA   Vuilleumier S., Chistoserdova L., Lee M.-C., Bringel F., Lajus A., Zhou Y.,
RA   Gourion B., Barbe V., Chang J., Cruveiller S., Dossat C., Gillett W.,
RA   Gruffaz C., Haugen E., Hourcade E., Levy R., Mangenot S., Muller E.,
RA   Nadalig T., Pagni M., Penny C., Peyraud R., Robinson D.G., Roche D.,
RA   Rouy Z., Saenampechek C., Salvignol G., Vallenet D., Wu Z., Marx C.J.,
RA   Vorholt J.A., Olson M.V., Kaul R., Weissenbach J., Medigue C.,
RA   Lidstrom M.E.;
RT   "Methylobacterium genome sequences: a reference blueprint to investigate
RT   microbial metabolism of C1 compounds from natural and industrial sources.";
RL   PLoS ONE 4:E5584-E5584(2009).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 176-205.
RX   PubMed=1885555; DOI=10.1128/jb.173.18.5909-5913.1991;
RA   Chistoserdov A.Y., Lidstrom M.E.;
RT   "The small-subunit polypeptide of methylamine dehydrogenase from
RT   Methylobacterium extorquens AM1 has an unusual leader sequence.";
RL   J. Bacteriol. 173:5909-5913(1991).
CC   -!- FUNCTION: May be specifically involved in the processing, transport,
CC       and/or maturation of the MADH beta-subunit.
CC   -!- PATHWAY: One-carbon metabolism; methylamine degradation.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass membrane
CC       protein {ECO:0000305}.
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DR   EMBL; L26406; AAB46935.1; -; Genomic_DNA.
DR   EMBL; CP001510; ACS40530.1; -; Genomic_DNA.
DR   EMBL; M57963; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   PIR; A38123; A38123.
DR   RefSeq; WP_012753045.1; NC_012808.1.
DR   AlphaFoldDB; Q49126; -.
DR   SMR; Q49126; -.
DR   STRING; 272630.MexAM1_META1p2772; -.
DR   EnsemblBacteria; ACS40530; ACS40530; MexAM1_META1p2772.
DR   KEGG; mea:Mex_1p2772; -.
DR   eggNOG; COG1225; Bacteria.
DR   HOGENOM; CLU_091361_0_0_5; -.
DR   OMA; YERVAPM; -.
DR   OrthoDB; 1617952at2; -.
DR   UniPathway; UPA00895; -.
DR   Proteomes; UP000009081; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0016209; F:antioxidant activity; IEA:InterPro.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR   GO; GO:0030416; P:methylamine metabolic process; IEA:InterPro.
DR   InterPro; IPR000866; AhpC/TSA.
DR   InterPro; IPR013478; MeN_DH_accessory.
DR   InterPro; IPR036249; Thioredoxin-like_sf.
DR   InterPro; IPR013766; Thioredoxin_domain.
DR   Pfam; PF00578; AhpC-TSA; 1.
DR   SUPFAM; SSF52833; SSF52833; 1.
DR   TIGRFAMs; TIGR02661; MauD; 1.
DR   PROSITE; PS51352; THIOREDOXIN_2; 1.
PE   4: Predicted;
KW   Membrane; Transmembrane; Transmembrane helix.
FT   CHAIN           1..205
FT                   /note="Methylamine utilization protein MauD"
FT                   /id="PRO_0000208927"
FT   TRANSMEM        5..25
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   DOMAIN          50..184
FT                   /note="Thioredoxin"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00691"
FT   CONFLICT        176..179
FT                   /note="ESLL -> CLQV (in Ref. 3)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   205 AA;  22233 MW;  78364F3DA07C1104 CRC64;
     MTMQFLIASN VLLWLALIGC AVLMLGLLRQ VGLLHERSSP MGAMITDHGP DVGDAAPTFD
     LPDHSGAMVR IGGPSALKRP TLLMFTAPTC PVCDKLFPLI KSIARAEKFS VVMISDGQPD
     EHQRFLAKHE LGDIRYVVSA EVGMAFQVGK IPYGVLLDPE GVIRAKGLTN TREHLESLLE
     ADKSGFASIQ QFMTSRKHSH DAKAA