ID   MAUR_KLEPN              Reviewed;         308 AA.
AC   P52684;
DT   01-OCT-1996, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-1996, sequence version 1.
DT   25-MAY-2022, entry version 80.
DE   RecName: Full=Malonate utilization transcriptional regulator;
GN   Name=mauR;
OS   Klebsiella pneumoniae.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Klebsiella/Raoultella group; Klebsiella.
OX   NCBI_TaxID=573;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=CG43;
RA   Peng H., Chang H., Chaou S., Deng W., Chiang F.;
RL   Submitted (SEP-1994) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Transcriptional regulator of the mau genes for malonate
CC       utilization.
CC   -!- SIMILARITY: Belongs to the LysR transcriptional regulatory family.
CC       {ECO:0000305}.
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DR   EMBL; U14004; AAA21364.1; -; Genomic_DNA.
DR   RefSeq; WP_004148289.1; NZ_WXZO01000032.1.
DR   AlphaFoldDB; P52684; -.
DR   SMR; P52684; -.
DR   PRIDE; P52684; -.
DR   PATRIC; fig|573.1353.peg.2115; -.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   CDD; cd08416; PBP2_MdcR; 1.
DR   Gene3D; 1.10.10.10; -; 1.
DR   InterPro; IPR005119; LysR_subst-bd.
DR   InterPro; IPR037400; MdcR_PBP2.
DR   InterPro; IPR000847; Tscrpt_reg_HTH_LysR.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   Pfam; PF00126; HTH_1; 1.
DR   Pfam; PF03466; LysR_substrate; 1.
DR   SUPFAM; SSF46785; SSF46785; 1.
DR   PROSITE; PS50931; HTH_LYSR; 1.
PE   3: Inferred from homology;
KW   DNA-binding; Transcription; Transcription regulation.
FT   CHAIN           1..308
FT                   /note="Malonate utilization transcriptional regulator"
FT                   /id="PRO_0000105670"
FT   DOMAIN          9..66
FT                   /note="HTH lysR-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00253"
FT   DNA_BIND        26..45
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00253"
SQ   SEQUENCE   308 AA;  34636 MW;  7B11348D13DB61C1 CRC64;
     MKDDINQEIT FRKLSVFMMF MAKGNIARTA EAMKLSSVSV HRALHTLEEG VGCPLFVHKG
     RNLLPLQAAW TLLEYCQDVI SLMNRGLEAT RKVAGVGQGR LRIGTLYSLT LETVPRIIMG
     MKLRRPELEL DLTMGSNQML LDMLEDDALD AILIATNEGE FNNTAFDVVP LFEDDIFLAA
     PATERLDASR LADLRDYADR KFVSLAEGFA TYAGFREAFH IAGFEPEIVT RVNDIFSMIS
     LVQAGVGFAL LPGRMKKVYE KDVQLLKLAE PYQMRQLISI VYSHHRERDA DLLALAAEGR
     MYARSINR