ID   MAZE1_MYCBO             Reviewed;         100 AA.
AC   P0A5F0; A0A1R3XZH8; P71775; X2BI30;
DT   15-MAR-2005, integrated into UniProtKB/Swiss-Prot.
DT   15-MAR-2005, sequence version 1.
DT   25-MAY-2022, entry version 69.
DE   RecName: Full=Probable antitoxin MazE1;
GN   Name=mazE1; OrderedLocusNames=BQ2027_MB1531;
OS   Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=233413;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-935 / AF2122/97;
RX   PubMed=12788972; DOI=10.1073/pnas.1130426100;
RA   Garnier T., Eiglmeier K., Camus J.-C., Medina N., Mansoor H., Pryor M.,
RA   Duthoy S., Grondin S., Lacroix C., Monsempe C., Simon S., Harris B.,
RA   Atkin R., Doggett J., Mayes R., Keating L., Wheeler P.R., Parkhill J.,
RA   Barrell B.G., Cole S.T., Gordon S.V., Hewinson R.G.;
RT   "The complete genome sequence of Mycobacterium bovis.";
RL   Proc. Natl. Acad. Sci. U.S.A. 100:7877-7882(2003).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], AND GENOME REANNOTATION.
RC   STRAIN=ATCC BAA-935 / AF2122/97;
RX   PubMed=28385856; DOI=10.1128/genomea.00157-17;
RA   Malone K.M., Farrell D., Stuber T.P., Schubert O.T., Aebersold R.,
RA   Robbe-Austerman S., Gordon S.V.;
RT   "Updated reference genome sequence and annotation of Mycobacterium bovis
RT   AF2122/97.";
RL   Genome Announc. 5:E00157-E00157(2017).
CC   -!- FUNCTION: Probable antitoxin component of a type II toxin-antitoxin
CC       (TA) system. Labile antitoxin that binds to cognate MazF1 toxin and
CC       counteracts its endoribonuclease activity.
CC       {ECO:0000250|UniProtKB:P9WJ91}.
CC   -!- SUBUNIT: Forms a complex with cognate toxin MazF1.
CC       {ECO:0000250|UniProtKB:P9WJ91}.
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DR   EMBL; LT708304; SIU00134.1; -; Genomic_DNA.
DR   RefSeq; NP_855183.1; NC_002945.3.
DR   RefSeq; WP_003900349.1; NC_002945.4.
DR   AlphaFoldDB; P0A5F0; -.
DR   SMR; P0A5F0; -.
DR   EnsemblBacteria; SIU00134; SIU00134; BQ2027_MB1531.
DR   GeneID; 45425474; -.
DR   PATRIC; fig|233413.5.peg.1673; -.
DR   OMA; RAWRNAR; -.
DR   Proteomes; UP000001419; Chromosome.
PE   3: Inferred from homology;
KW   Toxin-antitoxin system.
FT   CHAIN           1..100
FT                   /note="Probable antitoxin MazE1"
FT                   /id="PRO_0000103859"
FT   REGION          77..100
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   100 AA;  11205 MW;  6AC437A0F88DA20D CRC64;
     MPFLVALSGI ISGVRDHSMT VRLDQQTRQR LQDIVKGGYR SANAAIVDAI NKRWEALHDE
     QLDAAYAAAI HDNPAYPYES EAERSAARAR RNARQQRSAQ