ID   MAZE1_MYCTU             Reviewed;          57 AA.
AC   P0CL57; L0T5F4;
DT   05-APR-2011, integrated into UniProtKB/Swiss-Prot.
DT   05-APR-2011, sequence version 1.
DT   25-MAY-2022, entry version 34.
DE   RecName: Full=Probable antitoxin MazE1 {ECO:0000305};
GN   Name=mazE1; OrderedLocusNames=Rv0456B;
OS   Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=83332;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 25618 / H37Rv;
RX   PubMed=9634230; DOI=10.1038/31159;
RA   Cole S.T., Brosch R., Parkhill J., Garnier T., Churcher C.M., Harris D.E.,
RA   Gordon S.V., Eiglmeier K., Gas S., Barry C.E. III, Tekaia F., Badcock K.,
RA   Basham D., Brown D., Chillingworth T., Connor R., Davies R.M., Devlin K.,
RA   Feltwell T., Gentles S., Hamlin N., Holroyd S., Hornsby T., Jagels K.,
RA   Krogh A., McLean J., Moule S., Murphy L.D., Oliver S., Osborne J.,
RA   Quail M.A., Rajandream M.A., Rogers J., Rutter S., Seeger K., Skelton S.,
RA   Squares S., Squares R., Sulston J.E., Taylor K., Whitehead S.,
RA   Barrell B.G.;
RT   "Deciphering the biology of Mycobacterium tuberculosis from the complete
RT   genome sequence.";
RL   Nature 393:537-544(1998).
RN   [2]
RP   IDENTIFICATION, AND POSSIBLE FUNCTION.
RC   STRAIN=ATCC 25618 / H37Rv;
RX   PubMed=15718296; DOI=10.1093/nar/gki201;
RA   Pandey D.P., Gerdes K.;
RT   "Toxin-antitoxin loci are highly abundant in free-living but lost from
RT   host-associated prokaryotes.";
RL   Nucleic Acids Res. 33:966-976(2005).
CC   -!- FUNCTION: Antitoxin component of a type II toxin-antitoxin (TA) system.
CC       {ECO:0000305}.
CC   -!- SUBUNIT: Forms a complex with cognate toxin MazF1.
CC       {ECO:0000250|UniProtKB:O53451}.
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DR   EMBL; AL123456; CCP43189.1; -; Genomic_DNA.
DR   RefSeq; WP_003903009.1; NZ_NVQJ01000002.1.
DR   RefSeq; YP_007409102.1; NC_000962.3.
DR   AlphaFoldDB; P0CL57; -.
DR   STRING; 83332.Rv0456B; -.
DR   GeneID; 14515889; -.
DR   KEGG; mtu:Rv0456B; -.
DR   TubercuList; Rv0456B; -.
DR   Proteomes; UP000001584; Chromosome.
PE   3: Inferred from homology;
KW   Reference proteome; Toxin-antitoxin system.
FT   CHAIN           1..57
FT                   /note="Probable antitoxin MazE1"
FT                   /id="PRO_0000406295"
SQ   SEQUENCE   57 AA;  6791 MW;  050EA75E1CF19B69 CRC64;
     MTTYYYVLLS VTTWVGLRHE AKRELVYRGR RSIGRMPREW ACRRSRRFAA NGVDAAR