ID   MAZE4_MYCTO             Reviewed;         100 AA.
AC   P9WJ90; L0T8F3; P0A5E9; P71775;
DT   16-APR-2014, integrated into UniProtKB/Swiss-Prot.
DT   16-APR-2014, sequence version 1.
DT   25-MAY-2022, entry version 35.
DE   RecName: Full=Probable antitoxin MazE4;
GN   Name=mazE4; OrderedLocusNames=MT1541;
OS   Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=83331;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CDC 1551 / Oshkosh;
RX   PubMed=12218036; DOI=10.1128/jb.184.19.5479-5490.2002;
RA   Fleischmann R.D., Alland D., Eisen J.A., Carpenter L., White O.,
RA   Peterson J.D., DeBoy R.T., Dodson R.J., Gwinn M.L., Haft D.H., Hickey E.K.,
RA   Kolonay J.F., Nelson W.C., Umayam L.A., Ermolaeva M.D., Salzberg S.L.,
RA   Delcher A., Utterback T.R., Weidman J.F., Khouri H.M., Gill J., Mikula A.,
RA   Bishai W., Jacobs W.R. Jr., Venter J.C., Fraser C.M.;
RT   "Whole-genome comparison of Mycobacterium tuberculosis clinical and
RT   laboratory strains.";
RL   J. Bacteriol. 184:5479-5490(2002).
CC   -!- FUNCTION: Antitoxin component of a type II toxin-antitoxin (TA) system.
CC       Labile antitoxin that binds to cognate MazF4 toxin and counteracts its
CC       endoribonuclease activity. {ECO:0000250|UniProtKB:P9WJ91}.
CC   -!- SUBUNIT: Forms a complex with cognate toxin MazF4.
CC       {ECO:0000250|UniProtKB:P9WJ91}.
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DR   EMBL; AE000516; AAK45808.1; -; Genomic_DNA.
DR   PIR; A70712; A70712.
DR   RefSeq; WP_003917487.1; NZ_KK341227.1.
DR   AlphaFoldDB; P9WJ90; -.
DR   SMR; P9WJ90; -.
DR   EnsemblBacteria; AAK45808; AAK45808; MT1541.
DR   KEGG; mtc:MT1541; -.
DR   PATRIC; fig|83331.31.peg.1658; -.
DR   HOGENOM; CLU_2480056_0_0_11; -.
DR   Proteomes; UP000001020; Chromosome.
PE   3: Inferred from homology;
KW   Toxin-antitoxin system.
FT   CHAIN           1..100
FT                   /note="Probable antitoxin MazE4"
FT                   /id="PRO_0000427871"
FT   REGION          77..100
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   100 AA;  11186 MW;  2B7E2C1AF89D68B7 CRC64;
     MPFLVALSGI ISGVHDHSMT VRLDQQTRQR LQDIVKGGYR SANAAIVDAI NKRWEALHDE
     QLDAAYAAAI HDNPAYPYES EAERSAARAR RNARQQRSAQ