ID   MAZE5_MYCTO             Reviewed;         125 AA.
AC   P9WJ88; L0TAV7; P95271; Q7D7Q7;
DT   16-APR-2014, integrated into UniProtKB/Swiss-Prot.
DT   16-APR-2014, sequence version 1.
DT   25-MAY-2022, entry version 33.
DE   RecName: Full=Antitoxin MazE5;
GN   Name=mazE5; OrderedLocusNames=MT1993;
OS   Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=83331;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CDC 1551 / Oshkosh;
RX   PubMed=12218036; DOI=10.1128/jb.184.19.5479-5490.2002;
RA   Fleischmann R.D., Alland D., Eisen J.A., Carpenter L., White O.,
RA   Peterson J.D., DeBoy R.T., Dodson R.J., Gwinn M.L., Haft D.H., Hickey E.K.,
RA   Kolonay J.F., Nelson W.C., Umayam L.A., Ermolaeva M.D., Salzberg S.L.,
RA   Delcher A., Utterback T.R., Weidman J.F., Khouri H.M., Gill J., Mikula A.,
RA   Bishai W., Jacobs W.R. Jr., Venter J.C., Fraser C.M.;
RT   "Whole-genome comparison of Mycobacterium tuberculosis clinical and
RT   laboratory strains.";
RL   J. Bacteriol. 184:5479-5490(2002).
CC   -!- FUNCTION: Antitoxin component of a type II toxin-antitoxin (TA) system.
CC       Labile antitoxin that binds to its cognate MazF5 endoribonuclease toxin
CC       and neutralizes its activity. {ECO:0000250|UniProtKB:P9WJ89}.
CC   -!- SUBUNIT: Forms a complex with cognate toxin MazF5.
CC       {ECO:0000250|UniProtKB:P9WJ89}.
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DR   EMBL; AE000516; AAK46265.1; -; Genomic_DNA.
DR   PIR; C70637; C70637.
DR   RefSeq; WP_003409780.1; NZ_KK341227.1.
DR   AlphaFoldDB; P9WJ88; -.
DR   SMR; P9WJ88; -.
DR   EnsemblBacteria; AAK46265; AAK46265; MT1993.
DR   GeneID; 45427974; -.
DR   KEGG; mtc:MT1993; -.
DR   PATRIC; fig|83331.31.peg.2147; -.
DR   HOGENOM; CLU_2228852_0_0_11; -.
DR   Proteomes; UP000001020; Chromosome.
PE   3: Inferred from homology;
KW   Toxin-antitoxin system.
FT   CHAIN           1..125
FT                   /note="Antitoxin MazE5"
FT                   /id="PRO_0000427872"
SQ   SEQUENCE   125 AA;  13592 MW;  C4EE6301FA8ACD70 CRC64;
     MKTARLQVTL RCAVDLINSS SDQCFARIEH VASDQADPRP GVWHSSGMNR IRLSTTVDAA
     LLTSARDMRA GITDAALIDE ALAALLARHR SAEVDASYAA YDKHPVDEPD EWGDLASWRR
     AAGDS