ID   MAZE_STAS1              Reviewed;          56 AA.
AC   Q49Z23;
DT   29-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT   13-SEP-2005, sequence version 1.
DT   25-MAY-2022, entry version 80.
DE   RecName: Full=Antitoxin MazE;
GN   Name=mazE; OrderedLocusNames=SSP0808;
OS   Staphylococcus saprophyticus subsp. saprophyticus (strain ATCC 15305 / DSM
OS   20229 / NCIMB 8711 / NCTC 7292 / S-41).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;
OC   Staphylococcus.
OX   NCBI_TaxID=342451;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 15305 / DSM 20229 / NCIMB 8711 / NCTC 7292 / S-41;
RX   PubMed=16135568; DOI=10.1073/pnas.0502950102;
RA   Kuroda M., Yamashita A., Hirakawa H., Kumano M., Morikawa K., Higashide M.,
RA   Maruyama A., Inose Y., Matoba K., Toh H., Kuhara S., Hattori M., Ohta T.;
RT   "Whole genome sequence of Staphylococcus saprophyticus reveals the
RT   pathogenesis of uncomplicated urinary tract infection.";
RL   Proc. Natl. Acad. Sci. U.S.A. 102:13272-13277(2005).
CC   -!- FUNCTION: Antitoxin component of a type II toxin-antitoxin (TA) system.
CC       Labile antitoxin that binds to cognate MazF toxin and counteracts its
CC       endoribonuclease activity. {ECO:0000250|UniProtKB:P0C7B4}.
CC   -!- SUBUNIT: Forms a complex with cognate toxin MazF which inhibits the
CC       endoribonuclease activity of MazF. {ECO:0000250|UniProtKB:P0C7B4}.
CC   -!- SIMILARITY: Belongs to the MazE/EndoAI family. {ECO:0000305}.
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DR   EMBL; AP008934; BAE17953.1; -; Genomic_DNA.
DR   RefSeq; WP_011302702.1; NZ_MTGA01000032.1.
DR   AlphaFoldDB; Q49Z23; -.
DR   SMR; Q49Z23; -.
DR   STRING; 342451.SSP0808; -.
DR   EnsemblBacteria; BAE17953; BAE17953; SSP0808.
DR   KEGG; ssp:SSP0808; -.
DR   PATRIC; fig|342451.11.peg.810; -.
DR   eggNOG; ENOG50305BV; Bacteria.
DR   HOGENOM; CLU_3012108_0_0_9; -.
DR   OMA; AYSVECE; -.
DR   OrthoDB; 2014469at2; -.
DR   Proteomes; UP000006371; Chromosome.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR   Gene3D; 1.10.1220.10; -; 1.
DR   InterPro; IPR013321; Arc_rbn_hlx_hlx.
PE   3: Inferred from homology;
KW   Reference proteome; Toxin-antitoxin system.
FT   CHAIN           1..56
FT                   /note="Antitoxin MazE"
FT                   /id="PRO_0000330724"
SQ   SEQUENCE   56 AA;  6332 MW;  77C3B50C7C29DC39 CRC64;
     MASFNQSRIH NIEQLLKEGY SQMADLNLSL AAEAFPFECE ACDCNEVYIS SKNNNE