ID   MB212_XENTR             Reviewed;         359 AA.
AC   A4IIW0;
DT   04-DEC-2007, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-2007, sequence version 1.
DT   03-AUG-2022, entry version 53.
DE   RecName: Full=Protein mab-21-like 2;
GN   Name=mab21l2;
OS   Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana.
OX   NCBI_TaxID=8364;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Brain;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Required for several aspects of embryonic development
CC       including normal development of the eye.
CC       {ECO:0000250|UniProtKB:Q8BPP1}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:Q9Y586}. Cytoplasm
CC       {ECO:0000250|UniProtKB:Q9Y586}. Note=Predominantly localizes to the
CC       nucleus, with some cytoplasmic localization.
CC       {ECO:0000250|UniProtKB:Q9Y586}.
CC   -!- SIMILARITY: Belongs to the mab-21 family. {ECO:0000305}.
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DR   EMBL; BC136175; AAI36176.1; -; mRNA.
DR   RefSeq; NP_001096455.1; NM_001102985.1.
DR   AlphaFoldDB; A4IIW0; -.
DR   SMR; A4IIW0; -.
DR   STRING; 8364.ENSXETP00000041830; -.
DR   DNASU; 100125071; -.
DR   Ensembl; ENSXETT00000086699; ENSXETP00000090956; ENSXETG00000037146.
DR   GeneID; 100125071; -.
DR   KEGG; xtr:100125071; -.
DR   CTD; 10586; -.
DR   Xenbase; XB-GENE-983448; mab21l2.
DR   InParanoid; A4IIW0; -.
DR   OrthoDB; 771781at2759; -.
DR   Proteomes; UP000008143; Chromosome 1.
DR   Proteomes; UP000790000; Unplaced.
DR   Bgee; ENSXETG00000037146; Expressed in neurula embryo and 5 other tissues.
DR   GO; GO:0005737; C:cytoplasm; ISS:UniProtKB.
DR   GO; GO:0005634; C:nucleus; ISS:UniProtKB.
DR   GO; GO:0061386; P:closure of optic fissure; IEA:Ensembl.
DR   GO; GO:0061303; P:cornea development in camera-type eye; IEA:Ensembl.
DR   GO; GO:0048701; P:embryonic cranial skeleton morphogenesis; IEA:Ensembl.
DR   GO; GO:0048484; P:enteric nervous system development; IEA:Ensembl.
DR   GO; GO:0001654; P:eye development; ISS:UniProtKB.
DR   GO; GO:0002089; P:lens morphogenesis in camera-type eye; IEA:Ensembl.
DR   GO; GO:0060041; P:retina development in camera-type eye; IEA:Ensembl.
DR   InterPro; IPR024810; Mab-21_dom.
DR   InterPro; IPR020950; Mab21-l2.
DR   PANTHER; PTHR10656:SF37; PTHR10656:SF37; 1.
DR   Pfam; PF03281; Mab-21; 1.
DR   SMART; SM01265; Mab-21; 1.
PE   2: Evidence at transcript level;
KW   Cytoplasm; Developmental protein; Nucleus; Reference proteome.
FT   CHAIN           1..359
FT                   /note="Protein mab-21-like 2"
FT                   /id="PRO_0000312792"
SQ   SEQUENCE   359 AA;  40858 MW;  BE836ED8A4CDE952 CRC64;
     MIAAQAKLVY QLNKYYSERC QARKAAIAKT IREVCKVVSD VLKEVEVQEP RFISSLTEID
     ARYEGLEVVS PTEFEVVLYL NQMGVFNFVD DGSLPGCAVL KLSDGRKRSM SLWVEFITAS
     GYLSARKIRS RFQTLVAQAV DKCSYRDVVK MIADTSEVKL RIRERYIVQI TPAFKCTGIW
     PRSAAQWPLP HIPWPGPNRV AEVKAEGFNL LSKECYSLTG KQSSAESDAW VLQFAEAENR
     LLLGGCRSKC LSVLKTLRDR HLELPGQPLN NYHMKTLLLY ECEKHPRETD WDEACLGDRL
     NGILLQLISC LQCRRCPHYF LPNLDLFQGK PHSALESAAK QTWRLAREIL TNPKSLDKL