ID   MB21L_DROME             Reviewed;         368 AA.
AC   Q9Y106;
DT   04-DEC-2007, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1999, sequence version 1.
DT   03-AUG-2022, entry version 128.
DE   RecName: Full=Protein mab-21-like;
GN   ORFNames=CG4766;
OS   Drosophila melanogaster (Fruit fly).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC   Drosophilidae; Drosophila; Sophophora.
OX   NCBI_TaxID=7227;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Berkeley;
RX   PubMed=10731132; DOI=10.1126/science.287.5461.2185;
RA   Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D.,
RA   Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F.,
RA   George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N.,
RA   Sutton G.G., Wortman J.R., Yandell M.D., Zhang Q., Chen L.X., Brandon R.C.,
RA   Rogers Y.-H.C., Blazej R.G., Champe M., Pfeiffer B.D., Wan K.H., Doyle C.,
RA   Baxter E.G., Helt G., Nelson C.R., Miklos G.L.G., Abril J.F., Agbayani A.,
RA   An H.-J., Andrews-Pfannkoch C., Baldwin D., Ballew R.M., Basu A.,
RA   Baxendale J., Bayraktaroglu L., Beasley E.M., Beeson K.Y., Benos P.V.,
RA   Berman B.P., Bhandari D., Bolshakov S., Borkova D., Botchan M.R., Bouck J.,
RA   Brokstein P., Brottier P., Burtis K.C., Busam D.A., Butler H., Cadieu E.,
RA   Center A., Chandra I., Cherry J.M., Cawley S., Dahlke C., Davenport L.B.,
RA   Davies P., de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I.,
RA   Dietz S.M., Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C.,
RA   Dunn P., Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S.,
RA   Fleischmann W., Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M.,
RA   Glasser K., Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M.,
RA   Harris N.L., Harvey D.A., Heiman T.J., Hernandez J.R., Houck J., Hostin D.,
RA   Houston K.A., Howland T.J., Wei M.-H., Ibegwam C., Jalali M., Kalush F.,
RA   Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A., Kimmel B.E., Kodira C.D.,
RA   Kraft C.L., Kravitz S., Kulp D., Lai Z., Lasko P., Lei Y., Levitsky A.A.,
RA   Li J.H., Li Z., Liang Y., Lin X., Liu X., Mattei B., McIntosh T.C.,
RA   McLeod M.P., McPherson D., Merkulov G., Milshina N.V., Mobarry C.,
RA   Morris J., Moshrefi A., Mount S.M., Moy M., Murphy B., Murphy L.,
RA   Muzny D.M., Nelson D.L., Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R.,
RA   Pacleb J.M., Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V.,
RA   Reese M.G., Reinert K., Remington K., Saunders R.D.C., Scheeler F.,
RA   Shen H., Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T.J.,
RA   Spier E., Spradling A.C., Stapleton M., Strong R., Sun E., Svirskas R.,
RA   Tector C., Turner R., Venter E., Wang A.H., Wang X., Wang Z.-Y.,
RA   Wassarman D.A., Weinstock G.M., Weissenbach J., Williams S.M., Woodage T.,
RA   Worley K.C., Wu D., Yang S., Yao Q.A., Ye J., Yeh R.-F., Zaveri J.S.,
RA   Zhan M., Zhang G., Zhao Q., Zheng L., Zheng X.H., Zhong F.N., Zhong W.,
RA   Zhou X., Zhu S.C., Zhu X., Smith H.O., Gibbs R.A., Myers E.W., Rubin G.M.,
RA   Venter J.C.;
RT   "The genome sequence of Drosophila melanogaster.";
RL   Science 287:2185-2195(2000).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=Berkeley;
RX   PubMed=12537572; DOI=10.1186/gb-2002-3-12-research0083;
RA   Misra S., Crosby M.A., Mungall C.J., Matthews B.B., Campbell K.S.,
RA   Hradecky P., Huang Y., Kaminker J.S., Millburn G.H., Prochnik S.E.,
RA   Smith C.D., Tupy J.L., Whitfield E.J., Bayraktaroglu L., Berman B.P.,
RA   Bettencourt B.R., Celniker S.E., de Grey A.D.N.J., Drysdale R.A.,
RA   Harris N.L., Richter J., Russo S., Schroeder A.J., Shu S.Q., Stapleton M.,
RA   Yamada C., Ashburner M., Gelbart W.M., Rubin G.M., Lewis S.E.;
RT   "Annotation of the Drosophila melanogaster euchromatic genome: a systematic
RT   review.";
RL   Genome Biol. 3:RESEARCH0083.1-RESEARCH0083.22(2002).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RX   PubMed=10731138; DOI=10.1126/science.287.5461.2222;
RA   Rubin G.M., Hong L., Brokstein P., Evans-Holm M., Frise E., Stapleton M.,
RA   Harvey D.A.;
RT   "A Drosophila complementary DNA resource.";
RL   Science 287:2222-2224(2000).
CC   -!- INTERACTION:
CC       Q9Y106; Q9VYX0: c; NbExp=3; IntAct=EBI-98298, EBI-130372;
CC   -!- SIMILARITY: Belongs to the mab-21 family. {ECO:0000305}.
CC   -!- CAUTION: It is uncertain whether Met-1 or Met-7 is the initiator.
CC       {ECO:0000305}.
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DR   EMBL; AE014298; AAF46111.1; -; Genomic_DNA.
DR   EMBL; AF145667; AAD38642.1; -; mRNA.
DR   RefSeq; NP_572287.1; NM_132059.3.
DR   AlphaFoldDB; Q9Y106; -.
DR   SMR; Q9Y106; -.
DR   BioGRID; 58030; 3.
DR   IntAct; Q9Y106; 22.
DR   STRING; 7227.FBpp0070856; -.
DR   PaxDb; Q9Y106; -.
DR   DNASU; 31533; -.
DR   EnsemblMetazoa; FBtr0070891; FBpp0070856; FBgn0027546.
DR   GeneID; 31533; -.
DR   KEGG; dme:Dmel_CG4766; -.
DR   UCSC; CG4766-RA; d. melanogaster.
DR   FlyBase; FBgn0027546; CG4766.
DR   VEuPathDB; VectorBase:FBgn0027546; -.
DR   eggNOG; KOG3963; Eukaryota.
DR   GeneTree; ENSGT01050000244827; -.
DR   HOGENOM; CLU_045315_0_0_1; -.
DR   InParanoid; Q9Y106; -.
DR   OMA; RCLSMLK; -.
DR   OrthoDB; 771781at2759; -.
DR   PhylomeDB; Q9Y106; -.
DR   BioGRID-ORCS; 31533; 0 hits in 3 CRISPR screens.
DR   GenomeRNAi; 31533; -.
DR   PRO; PR:Q9Y106; -.
DR   Proteomes; UP000000803; Chromosome X.
DR   Bgee; FBgn0027546; Expressed in second segment of antenna (Drosophila) and 5 other tissues.
DR   ExpressionAtlas; Q9Y106; baseline and differential.
DR   Genevisible; Q9Y106; DM.
DR   GO; GO:0005737; C:cytoplasm; ISS:FlyBase.
DR   GO; GO:0005634; C:nucleus; ISS:FlyBase.
DR   GO; GO:0001654; P:eye development; ISS:FlyBase.
DR   InterPro; IPR024810; Mab-21_dom.
DR   Pfam; PF03281; Mab-21; 1.
DR   SMART; SM01265; Mab-21; 1.
PE   1: Evidence at protein level;
KW   Reference proteome.
FT   CHAIN           1..368
FT                   /note="Protein mab-21-like"
FT                   /id="PRO_0000312799"
SQ   SEQUENCE   368 AA;  42336 MW;  2270DF4103488F0C CRC64;
     MLVPPDMMAA QTRMVYQMNR FCTERVQARM YKTATAIREI CKIVQDILKE VELQEPRFIS
     SLVECNGRFE GVEVISPNEF EIVLYLNQMG VFNFVDDGTL PGCAVLKLSD GRKRSMSLWV
     EFITASGYLS SRKIRARFQT LVAQACDKSV YRDMVKMVGD TSEVKLRIRE RFVVQITPAF
     KCSGIWPRSA AHWPVPHLPW PHPNIVAEVK TEGFDLLSKE SVIMQNKNNN AASMEGDAWV
     LSFFEAENRL LQGGCRRRCL SMLKTLRDRH LDLPGNPISA YHLKNLLLYE CEKHPRDFEW
     DEGCIADRIN GIFLQLISCL QYRRCPHYFL PALDMFKGKS PSALEQAAKQ VWRLTRELLT
     NANAFEKL