MB3L5_HUMAN
ID MB3L5_HUMAN Reviewed; 208 AA.
AC A6NJ08;
DT 02-SEP-2008, integrated into UniProtKB/Swiss-Prot.
DT 24-JUL-2007, sequence version 1.
DT 03-AUG-2022, entry version 93.
DE RecName: Full=Putative methyl-CpG-binding domain protein 3-like 5;
DE Short=MBD3-like protein 5;
GN Name=MBD3L5;
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Homo.
OX NCBI_TaxID=9606;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=15057824; DOI=10.1038/nature02399;
RA Grimwood J., Gordon L.A., Olsen A.S., Terry A., Schmutz J., Lamerdin J.E.,
RA Hellsten U., Goodstein D., Couronne O., Tran-Gyamfi M., Aerts A.,
RA Altherr M., Ashworth L., Bajorek E., Black S., Branscomb E., Caenepeel S.,
RA Carrano A.V., Caoile C., Chan Y.M., Christensen M., Cleland C.A.,
RA Copeland A., Dalin E., Dehal P., Denys M., Detter J.C., Escobar J.,
RA Flowers D., Fotopulos D., Garcia C., Georgescu A.M., Glavina T., Gomez M.,
RA Gonzales E., Groza M., Hammon N., Hawkins T., Haydu L., Ho I., Huang W.,
RA Israni S., Jett J., Kadner K., Kimball H., Kobayashi A., Larionov V.,
RA Leem S.-H., Lopez F., Lou Y., Lowry S., Malfatti S., Martinez D.,
RA McCready P.M., Medina C., Morgan J., Nelson K., Nolan M., Ovcharenko I.,
RA Pitluck S., Pollard M., Popkie A.P., Predki P., Quan G., Ramirez L.,
RA Rash S., Retterer J., Rodriguez A., Rogers S., Salamov A., Salazar A.,
RA She X., Smith D., Slezak T., Solovyev V., Thayer N., Tice H., Tsai M.,
RA Ustaszewska A., Vo N., Wagner M., Wheeler J., Wu K., Xie G., Yang J.,
RA Dubchak I., Furey T.S., DeJong P., Dickson M., Gordon D., Eichler E.E.,
RA Pennacchio L.A., Richardson P., Stubbs L., Rokhsar D.S., Myers R.M.,
RA Rubin E.M., Lucas S.M.;
RT "The DNA sequence and biology of human chromosome 19.";
RL Nature 428:529-535(2004).
CC -!- MISCELLANEOUS: The MBD3L proteins are encoded by strongly repeated
CC regions of the 19p13 chromosome. The exact number of functional copies
CC is unclear, and some of them may represent pseudogenes.
CC -!- SIMILARITY: Belongs to the MBD3L family. {ECO:0000305}.
CC -!- CAUTION: Could be the product of a pseudogene. {ECO:0000305}.
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DR EMBL; AC010606; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR CCDS; CCDS45942.1; -.
DR RefSeq; NP_001129979.1; NM_001136507.1.
DR AlphaFoldDB; A6NJ08; -.
DR SMR; A6NJ08; -.
DR BioGRID; 129874; 1.
DR STRING; 9606.ENSP00000331435; -.
DR BioMuta; MBD3L5; -.
DR MassIVE; A6NJ08; -.
DR PaxDb; A6NJ08; -.
DR PeptideAtlas; A6NJ08; -.
DR PRIDE; A6NJ08; -.
DR ProteomicsDB; 1300; -.
DR Antibodypedia; 56497; 1 antibodies from 1 providers.
DR DNASU; 284428; -.
DR Ensembl; ENST00000329753.5; ENSP00000331435.4; ENSG00000237247.6.
DR GeneID; 284428; -.
DR KEGG; hsa:284428; -.
DR MANE-Select; ENST00000329753.5; ENSP00000331435.4; NM_001136507.2; NP_001129979.1.
DR UCSC; uc010xjl.3; human.
DR CTD; 284428; -.
DR GeneCards; MBD3L5; -.
DR HGNC; HGNC:37204; MBD3L5.
DR HPA; ENSG00000237247; Not detected.
DR neXtProt; NX_A6NJ08; -.
DR VEuPathDB; HostDB:ENSG00000237247; -.
DR eggNOG; KOG4161; Eukaryota.
DR GeneTree; ENSGT00950000183005; -.
DR InParanoid; A6NJ08; -.
DR OMA; VTDANIW; -.
DR OrthoDB; 1511703at2759; -.
DR PhylomeDB; A6NJ08; -.
DR TreeFam; TF325032; -.
DR PathwayCommons; A6NJ08; -.
DR BioGRID-ORCS; 284428; 17 hits in 594 CRISPR screens.
DR GenomeRNAi; 284428; -.
DR Pharos; A6NJ08; Tdark.
DR Proteomes; UP000005640; Chromosome 19.
DR RNAct; A6NJ08; protein.
DR Bgee; ENSG00000237247; Expressed in smooth muscle tissue and 3 other tissues.
DR Genevisible; A6NJ08; HS.
DR InterPro; IPR032343; MBD2/MBD3_p55-bd.
DR InterPro; IPR025884; MeCpG-bd_2/3_C_dom.
DR Pfam; PF14048; MBD_C; 1.
DR Pfam; PF16564; MBDa; 1.
PE 5: Uncertain;
KW Reference proteome.
FT CHAIN 1..208
FT /note="Putative methyl-CpG-binding domain protein 3-like 5"
FT /id="PRO_0000349235"
SQ SEQUENCE 208 AA; 22976 MW; 3A33C517B2635EEB CRC64;
MGEPAFTSFP SPPVLGKLKR NMMPWALQKK REIHMAKAHR RRAARSALPM RLTSCIFRRP
VTRIRSHPDN QVRRRKGDEH LEKPQQLCAY RRLQALQPCS SQGEGSSPLH LESVLSILAP
GTAGESLDRA GAERVRIPLE PTPGRFPAVA GGPTPGMGCQ LPPPLSGQLV TPADIRRQAR
RVKKARERLA KALQADRLAR QAEMLTGG