ID   MB3LB_HUMAN             Reviewed;         204 AA.
AC   A0A1B0GVZ6;
DT   27-SEP-2017, integrated into UniProtKB/Swiss-Prot.
DT   05-OCT-2016, sequence version 1.
DT   03-AUG-2022, entry version 30.
DE   RecName: Full=Methyl-CpG-binding domain protein 3-like 2B {ECO:0000312|HGNC:HGNC:53435};
GN   Name=MBD3L2B {ECO:0000312|HGNC:HGNC:53435};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
OX   NCBI_TaxID=9606;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=15057824; DOI=10.1038/nature02399;
RA   Grimwood J., Gordon L.A., Olsen A.S., Terry A., Schmutz J., Lamerdin J.E.,
RA   Hellsten U., Goodstein D., Couronne O., Tran-Gyamfi M., Aerts A.,
RA   Altherr M., Ashworth L., Bajorek E., Black S., Branscomb E., Caenepeel S.,
RA   Carrano A.V., Caoile C., Chan Y.M., Christensen M., Cleland C.A.,
RA   Copeland A., Dalin E., Dehal P., Denys M., Detter J.C., Escobar J.,
RA   Flowers D., Fotopulos D., Garcia C., Georgescu A.M., Glavina T., Gomez M.,
RA   Gonzales E., Groza M., Hammon N., Hawkins T., Haydu L., Ho I., Huang W.,
RA   Israni S., Jett J., Kadner K., Kimball H., Kobayashi A., Larionov V.,
RA   Leem S.-H., Lopez F., Lou Y., Lowry S., Malfatti S., Martinez D.,
RA   McCready P.M., Medina C., Morgan J., Nelson K., Nolan M., Ovcharenko I.,
RA   Pitluck S., Pollard M., Popkie A.P., Predki P., Quan G., Ramirez L.,
RA   Rash S., Retterer J., Rodriguez A., Rogers S., Salamov A., Salazar A.,
RA   She X., Smith D., Slezak T., Solovyev V., Thayer N., Tice H., Tsai M.,
RA   Ustaszewska A., Vo N., Wagner M., Wheeler J., Wu K., Xie G., Yang J.,
RA   Dubchak I., Furey T.S., DeJong P., Dickson M., Gordon D., Eichler E.E.,
RA   Pennacchio L.A., Richardson P., Stubbs L., Rokhsar D.S., Myers R.M.,
RA   Rubin E.M., Lucas S.M.;
RT   "The DNA sequence and biology of human chromosome 19.";
RL   Nature 428:529-535(2004).
CC   -!- MISCELLANEOUS: The MBD3L proteins are encoded by strongly repeated
CC       regions of the 19p13 chromosome. The exact number of functional copies
CC       is unclear, and some of them may represent pseudogenes. {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the MBD3L family. {ECO:0000305}.
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DR   EMBL; AC010606; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AC025278; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   AlphaFoldDB; A0A1B0GVZ6; -.
DR   SMR; A0A1B0GVZ6; -.
DR   BioMuta; MBD3L2B; -.
DR   MassIVE; A0A1B0GVZ6; -.
DR   Ensembl; ENST00000636986.2; ENSP00000489619.1; ENSG00000196589.7.
DR   Ensembl; ENST00000637800.1; ENSP00000490712.1; ENSG00000196589.7.
DR   MANE-Select; ENST00000636986.2; ENSP00000489619.1; NM_001364674.2; NP_001351603.1.
DR   GeneCards; MBD3L2B; -.
DR   HGNC; HGNC:53435; MBD3L2B.
DR   HPA; ENSG00000196589; Not detected.
DR   neXtProt; NX_A0A1B0GVZ6; -.
DR   OpenTargets; ENSG00000196589; -.
DR   VEuPathDB; HostDB:ENSG00000196589; -.
DR   GeneTree; ENSGT00950000183005; -.
DR   OMA; CQGEASS; -.
DR   PhylomeDB; A0A1B0GVZ6; -.
DR   Pharos; A0A1B0GVZ6; Tdark.
DR   PRO; PR:A0A1B0GVZ6; -.
DR   Proteomes; UP000005640; Chromosome 19.
DR   RNAct; A0A1B0GVZ6; protein.
DR   Bgee; ENSG00000196589; Expressed in ganglionic eminence and 3 other tissues.
DR   InterPro; IPR032343; MBD2/MBD3_p55-bd.
DR   InterPro; IPR025884; MeCpG-bd_2/3_C_dom.
DR   Pfam; PF14048; MBD_C; 1.
DR   Pfam; PF16564; MBDa; 1.
PE   3: Inferred from homology;
KW   Reference proteome.
FT   CHAIN           1..204
FT                   /note="Methyl-CpG-binding domain protein 3-like 2B"
FT                   /id="PRO_0000441416"
FT   REGION          126..145
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   204 AA;  22665 MW;  C75F15CB2C99DC06 CRC64;
     MGEPAFTSFP SLPVLGKLKR NMMPWALQKK REIHMAKAHR RRAARSALPM RLTSCIFRRP
     VTRIRSHPDN QVRRRKGDEH LEKPQQLCAY RRLQALQPCS SQGEGSSPLH LESVLSILAP
     GTAGESLDRA GAERVRSPLE PTPGRFPAVA GGPTPGMGCQ LPPPLSGQLV TPADIRRQAR
     RVKKARERLA KALQADRLAR RAEM