ID   ARGP_EDWI9              Reviewed;         297 AA.
AC   O52399; C5BAU1;
DT   30-MAY-2000, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-1998, sequence version 1.
DT   25-MAY-2022, entry version 120.
DE   RecName: Full=HTH-type transcriptional regulator ArgP {ECO:0000255|HAMAP-Rule:MF_00513};
GN   Name=argP {ECO:0000255|HAMAP-Rule:MF_00513}; Synonyms=iciA;
GN   OrderedLocusNames=NT01EI_3363;
OS   Edwardsiella ictaluri (strain 93-146).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Hafniaceae; Edwardsiella.
OX   NCBI_TaxID=634503;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=12542086; DOI=10.3354/dao052093;
RA   Moore M.M., Fernandez D.L., Thune R.L.;
RT   "Cloning and characterization of Edwardsiella ictaluri proteins expressed
RT   and recognized by the channel catfish Ictalurus punctatus immune response
RT   during infection.";
RL   Dis. Aquat. Organ. 52:93-107(2002).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=93-146;
RA   Williams M.L., Gillaspy A.F., Dyer D.W., Thune R.L., Waldbieser G.C.,
RA   Schuster S.C., Gipson J., Zaitshik J., Landry C., Lawrence M.L.;
RT   "Complete genome sequence of Edwardsiella ictaluri 93-146.";
RL   Submitted (MAR-2009) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Controls the transcription of genes involved in arginine and
CC       lysine metabolism. {ECO:0000255|HAMAP-Rule:MF_00513}.
CC   -!- SUBUNIT: Homodimer. {ECO:0000255|HAMAP-Rule:MF_00513}.
CC   -!- SIMILARITY: Belongs to the LysR transcriptional regulatory family.
CC       {ECO:0000305}.
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DR   EMBL; AF037440; AAB92569.1; -; Genomic_DNA.
DR   EMBL; CP001600; ACR70500.1; -; Genomic_DNA.
DR   RefSeq; WP_015872573.1; NC_012779.2.
DR   AlphaFoldDB; O52399; -.
DR   SMR; O52399; -.
DR   STRING; 67780.B6E78_08500; -.
DR   EnsemblBacteria; ACR70500; ACR70500; NT01EI_3363.
DR   GeneID; 7959662; -.
DR   KEGG; eic:NT01EI_3363; -.
DR   PATRIC; fig|634503.3.peg.2989; -.
DR   HOGENOM; CLU_063829_0_0_6; -.
DR   OMA; QQWKLDS; -.
DR   OrthoDB; 951478at2; -.
DR   Proteomes; UP000001485; Chromosome.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:UniProtKB-UniRule.
DR   Gene3D; 1.10.10.10; -; 1.
DR   HAMAP; MF_00513; HTH_type_ArgP; 1.
DR   InterPro; IPR017685; ArgP.
DR   InterPro; IPR023490; ArgP_Gammaproteobact.
DR   InterPro; IPR005119; LysR_subst-bd.
DR   InterPro; IPR000847; Tscrpt_reg_HTH_LysR.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   Pfam; PF00126; HTH_1; 1.
DR   Pfam; PF03466; LysR_substrate; 1.
DR   PRINTS; PR00039; HTHLYSR.
DR   SUPFAM; SSF46785; SSF46785; 1.
DR   TIGRFAMs; TIGR03298; argP; 1.
DR   PROSITE; PS50931; HTH_LYSR; 1.
PE   3: Inferred from homology;
KW   DNA-binding; Reference proteome; Transcription; Transcription regulation.
FT   CHAIN           1..297
FT                   /note="HTH-type transcriptional regulator ArgP"
FT                   /id="PRO_0000105644"
FT   DOMAIN          4..60
FT                   /note="HTH lysR-type"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00513"
FT   DNA_BIND        21..40
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00513"
SQ   SEQUENCE   297 AA;  33393 MW;  93BEC456B2419989 CRC64;
     MKRPDYRTLQ ALDAVIRERG FERAAQKLCI TQSAVSQRIK QLENLFGQPL LVRTVPPRPT
     EQGQRLLALL HQVELLEEEW LGNDNSSDGP LLLSLAVNAD SLATWLLPAL KPVLADSPLR
     LNLQVEDESR TQERLRRGEV VGAVSLQPQP LPSCLVDRLG ALDYLFCASP AFAARYFPNG
     VTRSSLLKAP AVAFDHLDDM HQAFLQQNFE LPPGSVPCHI VNSSEAFVQL ALQGTTCCML
     PHLQVERELR KGVLIDLTPG MVQRRMLYWH RFAPESRLMR RVTDALISHG RDVLRQD