ID   MBF1_SCHPO              Reviewed;         148 AA.
AC   O94700;
DT   16-AUG-2005, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-1999, sequence version 1.
DT   03-AUG-2022, entry version 120.
DE   RecName: Full=Multiprotein-bridging factor 1;
GN   Name=mbf1; ORFNames=SPBC83.17;
OS   Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC   Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC   Schizosaccharomyces.
OX   NCBI_TaxID=284812;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=972 / ATCC 24843;
RX   PubMed=11859360; DOI=10.1038/nature724;
RA   Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA   Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA   Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA   Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA   Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA   Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA   Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA   Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA   O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA   Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA   Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA   Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA   Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA   Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA   Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA   Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA   Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA   Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA   Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA   Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA   del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA   Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA   Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA   Nurse P.;
RT   "The genome sequence of Schizosaccharomyces pombe.";
RL   Nature 415:871-880(2002).
CC   -!- FUNCTION: Transcriptional coactivator that stimulates transcriptional
CC       activity by bridging regulatory proteins and TBP, thereby recruiting
CC       TBP to promoters occupied by DNA-binding regulators. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the MBF1 family. {ECO:0000305}.
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DR   EMBL; CU329671; CAB36879.1; -; Genomic_DNA.
DR   PIR; T40706; T40706.
DR   RefSeq; NP_595650.1; NM_001021544.2.
DR   AlphaFoldDB; O94700; -.
DR   SMR; O94700; -.
DR   BioGRID; 277706; 17.
DR   STRING; 4896.SPBC83.17.1; -.
DR   iPTMnet; O94700; -.
DR   MaxQB; O94700; -.
DR   PaxDb; O94700; -.
DR   PRIDE; O94700; -.
DR   EnsemblFungi; SPBC83.17.1; SPBC83.17.1:pep; SPBC83.17.
DR   GeneID; 2541192; -.
DR   KEGG; spo:SPBC83.17; -.
DR   PomBase; SPBC83.17; mbf1.
DR   VEuPathDB; FungiDB:SPBC83.17; -.
DR   eggNOG; KOG3398; Eukaryota.
DR   HOGENOM; CLU_112609_0_1_1; -.
DR   InParanoid; O94700; -.
DR   OMA; NKAHQGT; -.
DR   PhylomeDB; O94700; -.
DR   PRO; PR:O94700; -.
DR   Proteomes; UP000002485; Chromosome II.
DR   GO; GO:0005829; C:cytosol; HDA:PomBase.
DR   GO; GO:0005730; C:nucleolus; HDA:PomBase.
DR   GO; GO:0005634; C:nucleus; HDA:PomBase.
DR   GO; GO:0003677; F:DNA binding; ISM:PomBase.
DR   GO; GO:0003713; F:transcription coactivator activity; ISO:PomBase.
DR   GO; GO:1990145; P:maintenance of translational fidelity; TAS:PomBase.
DR   GO; GO:0045944; P:positive regulation of transcription by RNA polymerase II; ISO:PomBase.
DR   CDD; cd00093; HTH_XRE; 1.
DR   Gene3D; 1.10.260.40; -; 1.
DR   InterPro; IPR001387; Cro/C1-type_HTH.
DR   InterPro; IPR010982; Lambda_DNA-bd_dom_sf.
DR   InterPro; IPR013729; MBF1_N.
DR   Pfam; PF01381; HTH_3; 1.
DR   Pfam; PF08523; MBF1; 1.
DR   SMART; SM00530; HTH_XRE; 1.
DR   SUPFAM; SSF47413; SSF47413; 1.
DR   PROSITE; PS50943; HTH_CROC1; 1.
PE   3: Inferred from homology;
KW   Activator; DNA-binding; Reference proteome; Transcription;
KW   Transcription regulation.
FT   CHAIN           1..148
FT                   /note="Multiprotein-bridging factor 1"
FT                   /id="PRO_0000149812"
FT   DOMAIN          82..136
FT                   /note="HTH cro/C1-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00257"
FT   DNA_BIND        93..112
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00257"
FT   REGION          1..97
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   148 AA;  15979 MW;  9DF5FDBD94B46E41 CRC64;
     MSDWDTVTKI GSRAGPGART HVAKTQSQIN SARRAGAIVG TEKKYATGNK SQDPAGQHLT
     KIDRENEVKP PSTTGRSVAQ AIQKGRQAKG WAQKDLSQRI NEKPQVVNDY ESGRAIPNQQ
     VLSKMERALG IKLRGQNIGA PLGGPKKK