ID   ARGP_PSEAB              Reviewed;         300 AA.
AC   Q02H78;
DT   05-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   14-NOV-2006, sequence version 1.
DT   03-AUG-2022, entry version 89.
DE   RecName: Full=HTH-type transcriptional regulator ArgP {ECO:0000255|HAMAP-Rule:MF_00513};
GN   Name=argP {ECO:0000255|HAMAP-Rule:MF_00513}; Synonyms=iciA;
GN   OrderedLocusNames=PA14_56740;
OS   Pseudomonas aeruginosa (strain UCBPP-PA14).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
OC   Pseudomonadaceae; Pseudomonas.
OX   NCBI_TaxID=208963;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=UCBPP-PA14;
RX   PubMed=17038190; DOI=10.1186/gb-2006-7-10-r90;
RA   Lee D.G., Urbach J.M., Wu G., Liberati N.T., Feinbaum R.L., Miyata S.,
RA   Diggins L.T., He J., Saucier M., Deziel E., Friedman L., Li L., Grills G.,
RA   Montgomery K., Kucherlapati R., Rahme L.G., Ausubel F.M.;
RT   "Genomic analysis reveals that Pseudomonas aeruginosa virulence is
RT   combinatorial.";
RL   Genome Biol. 7:R90.1-R90.14(2006).
CC   -!- FUNCTION: Controls the transcription of genes involved in arginine and
CC       lysine metabolism. {ECO:0000255|HAMAP-Rule:MF_00513}.
CC   -!- SUBUNIT: Homodimer. {ECO:0000255|HAMAP-Rule:MF_00513}.
CC   -!- SIMILARITY: Belongs to the LysR transcriptional regulatory family.
CC       {ECO:0000305}.
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DR   EMBL; CP000438; ABJ13633.1; -; Genomic_DNA.
DR   RefSeq; WP_003120877.1; NZ_CP034244.1.
DR   AlphaFoldDB; Q02H78; -.
DR   SMR; Q02H78; -.
DR   PRIDE; Q02H78; -.
DR   EnsemblBacteria; ABJ13633; ABJ13633; PA14_56740.
DR   KEGG; pau:PA14_56740; -.
DR   HOGENOM; CLU_063829_0_0_6; -.
DR   OMA; WRNGGQL; -.
DR   BioCyc; PAER208963:G1G74-4778-MON; -.
DR   Proteomes; UP000000653; Chromosome.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:UniProtKB-UniRule.
DR   Gene3D; 1.10.10.10; -; 1.
DR   HAMAP; MF_00513; HTH_type_ArgP; 1.
DR   InterPro; IPR017685; ArgP.
DR   InterPro; IPR023490; ArgP_Gammaproteobact.
DR   InterPro; IPR005119; LysR_subst-bd.
DR   InterPro; IPR000847; Tscrpt_reg_HTH_LysR.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   Pfam; PF00126; HTH_1; 1.
DR   Pfam; PF03466; LysR_substrate; 1.
DR   PRINTS; PR00039; HTHLYSR.
DR   SUPFAM; SSF46785; SSF46785; 1.
DR   TIGRFAMs; TIGR03298; argP; 1.
DR   PROSITE; PS50931; HTH_LYSR; 1.
PE   3: Inferred from homology;
KW   DNA-binding; Transcription; Transcription regulation.
FT   CHAIN           1..300
FT                   /note="HTH-type transcriptional regulator ArgP"
FT                   /id="PRO_1000060880"
FT   DOMAIN          4..60
FT                   /note="HTH lysR-type"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00513"
FT   DNA_BIND        21..40
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00513"
SQ   SEQUENCE   300 AA;  32451 MW;  BFC7F298E51CFBE9 CRC64;
     MILFDYKLLA ALAAVVEQGG FERAAQALGL SQSAVSQRIK LLEARVGQPV LVRETPPHPT
     DLGRRLLNHV QQVRLLEGDL QRWVPNLDEG GAPERLRIAL NADSLATWWA AAVGDFCAER
     RVLLDLVVED QEVGLKRMRA GEVAGCVCGS ARPVAGARSL LLGAMRYRGL ASPDFIARHF
     PRGVEAAALA GVPAIVFGPD DLLQHRFLKD LGVEGGFIHH LCPSSEGFVR LTAGGLGWGL
     VPERQVQGEL ARGELVELLP GQVIDVPLYW HYWRNGGELL ASLTEHLLAR AGDGLVRVSG