ID   MBIA_ECOLI              Reviewed;         161 AA.
AC   P28697; A0A385XLV8; Q2MCH8;
DT   01-DEC-1992, integrated into UniProtKB/Swiss-Prot.
DT   07-JUN-2017, sequence version 3.
DT   03-AUG-2022, entry version 102.
DE   RecName: Full=Uncharacterized protein MbiA {ECO:0000305};
DE   AltName: Full=Modifier of biofilm {ECO:0000250|UniProtKB:Q8XA70};
GN   Name=mbiA {ECO:0000250|UniProtKB:Q8XA70};
GN   Synonyms=htgA {ECO:0000303|PubMed:8400364},
GN   htpY {ECO:0000303|PubMed:8478327}; OrderedLocusNames=b0012, JW5001;
OS   Escherichia coli (strain K12).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=83333;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA], AND INDUCTION.
RX   PubMed=8400364; DOI=10.3109/10425179309020832;
RA   James R., Dean D.O., Debbage J.;
RT   "Five open reading frames upstream of the dnaK gene of E. coli.";
RL   DNA Seq. 3:327-332(1993).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA], AND INDUCTION.
RC   STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX   PubMed=8478327; DOI=10.1128/jb.175.9.2613-2624.1993;
RA   Missiakas D., Georgopoulos C., Raina S.;
RT   "The Escherichia coli heat shock gene htpY: mutational analysis, cloning,
RT   sequencing, and transcriptional regulation.";
RL   J. Bacteriol. 175:2613-2624(1993).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12;
RX   PubMed=1630901; DOI=10.1093/nar/20.13.3305;
RA   Yura T., Mori H., Nagai H., Nagata T., Ishihama A., Fujita N., Isono K.,
RA   Mizobuchi K., Nakata A.;
RT   "Systematic sequencing of the Escherichia coli genome: analysis of the 0-
RT   2.4 min region.";
RL   Nucleic Acids Res. 20:3305-3308(1992).
RN   [4]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / MG1655 / ATCC 47076;
RX   PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA   Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA   Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA   Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B.,
RA   Shao Y.;
RT   "The complete genome sequence of Escherichia coli K-12.";
RL   Science 277:1453-1462(1997).
RN   [5]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX   PubMed=16738553; DOI=10.1038/msb4100049;
RA   Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA   Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT   "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655
RT   and W3110.";
RL   Mol. Syst. Biol. 2:E1-E5(2006).
RN   [6]
RP   INDUCTION.
RC   STRAIN=K12 / MG1655 / ATCC 47076;
RX   PubMed=16818608; DOI=10.1101/gad.1428206;
RA   Nonaka G., Blankschien M., Herman C., Gross C.A., Rhodius V.A.;
RT   "Regulon and promoter analysis of the E. coli heat-shock factor, sigma32,
RT   reveals a multifaceted cellular response to heat stress.";
RL   Genes Dev. 20:1776-1789(2006).
RN   [7]
RP   OVERLAP WITH YAAW.
RX   PubMed=18226237; DOI=10.1186/1471-2148-8-31;
RA   Delaye L., Deluna A., Lazcano A., Becerra A.;
RT   "The origin of a novel gene through overprinting in Escherichia coli.";
RL   BMC Evol. Biol. 8:31-31(2008).
CC   -!- INDUCTION: Was originally thought to be involved in heat shock response
CC       (PubMed:8400364, PubMed:8478327), however it was later shown not to be
CC       induced by sigma-32 (rpoH) (PubMed:16818608).
CC       {ECO:0000269|PubMed:16818608, ECO:0000269|PubMed:8400364,
CC       ECO:0000269|PubMed:8478327}.
CC   -!- CAUTION: This gene is encoded entirely within the yaaW gene on the
CC       opposite strand (PubMed:18226237). Disruptions of one gene are also
CC       usually disruptions in the other. {ECO:0000305,
CC       ECO:0000305|PubMed:18226237}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAA23992.1; Type=Erroneous initiation; Note=Extended N-terminus.; Evidence={ECO:0000305};
CC       Sequence=AAA23993.1; Type=Erroneous initiation; Note=Truncated N-terminus.; Evidence={ECO:0000305};
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DR   EMBL; X67700; CAA47932.1; -; Genomic_DNA.
DR   EMBL; L03720; AAA23992.1; ALT_INIT; Genomic_DNA.
DR   EMBL; L03720; AAA23993.1; ALT_INIT; Genomic_DNA.
DR   EMBL; U00096; AYC08161.1; -; Genomic_DNA.
DR   EMBL; AP009048; BAE76028.1; -; Genomic_DNA.
DR   PIR; A40623; A40623.
DR   AlphaFoldDB; P28697; -.
DR   PRIDE; P28697; -.
DR   EnsemblBacteria; AYC08161; AYC08161; b0012.
DR   EnsemblBacteria; BAE76028; BAE76028; BAE76028.
DR   KEGG; ecj:JW5001; -.
DR   EchoBASE; EB4305; -.
DR   HOGENOM; CLU_1537672_0_0_6; -.
DR   BioCyc; EcoCyc:EG11509-MON; -.
DR   PRO; PR:P28697; -.
DR   Proteomes; UP000000318; Chromosome.
DR   Proteomes; UP000000625; Chromosome.
PE   2: Evidence at transcript level;
KW   Reference proteome.
FT   CHAIN           1..161
FT                   /note="Uncharacterized protein MbiA"
FT                   /id="PRO_0000169847"
SQ   SEQUENCE   161 AA;  17637 MW;  EFB80E462DD4F1D8 CRC64;
     MRVSWLESKC DTPFANNLSF ISSGSSSSSS FTLASTACRN SCLCSSSIFF QVLRRNCSSN
     CCSISNVDIS LSAFSFNRFE TSSKMARYNL PCPRSLLAIL SPPKCCNSPA ISCQLRRCCS
     GCPSIDLNSS LRISTLERRV LPFSLWVSNR AKFANCSSLQ C