ID   ARGP_PSEF5              Reviewed;         299 AA.
AC   Q4K779;
DT   31-OCT-2006, integrated into UniProtKB/Swiss-Prot.
DT   02-AUG-2005, sequence version 1.
DT   25-MAY-2022, entry version 99.
DE   RecName: Full=HTH-type transcriptional regulator ArgP {ECO:0000255|HAMAP-Rule:MF_00513};
GN   Name=argP {ECO:0000255|HAMAP-Rule:MF_00513}; Synonyms=iciA;
GN   OrderedLocusNames=PFL_4823;
OS   Pseudomonas fluorescens (strain ATCC BAA-477 / NRRL B-23932 / Pf-5).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
OC   Pseudomonadaceae; Pseudomonas.
OX   NCBI_TaxID=220664;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-477 / NRRL B-23932 / Pf-5;
RX   PubMed=15980861; DOI=10.1038/nbt1110;
RA   Paulsen I.T., Press C.M., Ravel J., Kobayashi D.Y., Myers G.S.A.,
RA   Mavrodi D.V., DeBoy R.T., Seshadri R., Ren Q., Madupu R., Dodson R.J.,
RA   Durkin A.S., Brinkac L.M., Daugherty S.C., Sullivan S.A., Rosovitz M.J.,
RA   Gwinn M.L., Zhou L., Schneider D.J., Cartinhour S.W., Nelson W.C.,
RA   Weidman J., Watkins K., Tran K., Khouri H., Pierson E.A., Pierson L.S. III,
RA   Thomashow L.S., Loper J.E.;
RT   "Complete genome sequence of the plant commensal Pseudomonas fluorescens
RT   Pf-5.";
RL   Nat. Biotechnol. 23:873-878(2005).
CC   -!- FUNCTION: Controls the transcription of genes involved in arginine and
CC       lysine metabolism. {ECO:0000255|HAMAP-Rule:MF_00513}.
CC   -!- SUBUNIT: Homodimer. {ECO:0000255|HAMAP-Rule:MF_00513}.
CC   -!- SIMILARITY: Belongs to the LysR transcriptional regulatory family.
CC       {ECO:0000305}.
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DR   EMBL; CP000076; AAY94053.1; -; Genomic_DNA.
DR   RefSeq; WP_011063077.1; NC_004129.6.
DR   AlphaFoldDB; Q4K779; -.
DR   SMR; Q4K779; -.
DR   STRING; 220664.PFL_4823; -.
DR   EnsemblBacteria; AAY94053; AAY94053; PFL_4823.
DR   KEGG; pfl:PFL_4823; -.
DR   PATRIC; fig|220664.5.peg.4935; -.
DR   eggNOG; COG0583; Bacteria.
DR   HOGENOM; CLU_063829_0_0_6; -.
DR   OMA; WRNGGQL; -.
DR   OrthoDB; 951478at2; -.
DR   Proteomes; UP000008540; Chromosome.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:UniProtKB-UniRule.
DR   Gene3D; 1.10.10.10; -; 1.
DR   HAMAP; MF_00513; HTH_type_ArgP; 1.
DR   InterPro; IPR017685; ArgP.
DR   InterPro; IPR023490; ArgP_Gammaproteobact.
DR   InterPro; IPR005119; LysR_subst-bd.
DR   InterPro; IPR000847; Tscrpt_reg_HTH_LysR.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   Pfam; PF00126; HTH_1; 1.
DR   Pfam; PF03466; LysR_substrate; 1.
DR   PRINTS; PR00039; HTHLYSR.
DR   SUPFAM; SSF46785; SSF46785; 1.
DR   TIGRFAMs; TIGR03298; argP; 1.
DR   PROSITE; PS50931; HTH_LYSR; 1.
PE   3: Inferred from homology;
KW   DNA-binding; Reference proteome; Transcription; Transcription regulation.
FT   CHAIN           1..299
FT                   /note="HTH-type transcriptional regulator ArgP"
FT                   /id="PRO_0000258610"
FT   DOMAIN          2..58
FT                   /note="HTH lysR-type"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00513"
FT   DNA_BIND        19..38
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00513"
SQ   SEQUENCE   299 AA;  33223 MW;  5E4402C6E3ACB937 CRC64;
     MFDYKLLSAL AAVIEQAGFE RAAQVLGLSQ SAISQRIKLL EARVGQPVLV RVTPPAPTEI
     GRRLLNHVQQ VRLLERDLQS LVPALDEEGL PERLRIALNA DSLATWWAGA VGDFCAEHHL
     LLDLVVEDQT VGLKRMRAGE VAACVCASER PVAGARSLLL GAMRYRAMAS PEFIVRHFPQ
     GVRAEQLPRT PALVFGPDDF LQHRYLASLG VDGAFEHHLC PSSEGFIRLT EAGLGWGLVP
     ELQVREQLER GLLLELLPDK PIDVPLYWHH WRNGGQLLGL LTEHLARLSA QWLVPWEQP