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MBNL1_CHICK
ID   MBNL1_CHICK             Reviewed;         369 AA.
AC   Q5ZKW9;
DT   06-FEB-2007, integrated into UniProtKB/Swiss-Prot.
DT   23-NOV-2004, sequence version 1.
DT   03-AUG-2022, entry version 90.
DE   RecName: Full=Muscleblind-like protein 1;
GN   Name=MBNL1; ORFNames=RCJMB04_8n15;
OS   Gallus gallus (Chicken).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae;
OC   Phasianinae; Gallus.
OX   NCBI_TaxID=9031;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=CB; TISSUE=Bursa of Fabricius;
RX   PubMed=15642098; DOI=10.1186/gb-2004-6-1-r6;
RA   Caldwell R.B., Kierzek A.M., Arakawa H., Bezzubov Y., Zaim J., Fiedler P.,
RA   Kutter S., Blagodatski A., Kostovska D., Koter M., Plachy J., Carninci P.,
RA   Hayashizaki Y., Buerstedde J.-M.;
RT   "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene
RT   function analysis.";
RL   Genome Biol. 6:R6.1-R6.9(2005).
CC   -!- FUNCTION: Involved in pre-mRNA alternative splicing regulation. Binds
CC       to CUG triplet repeat in RNA (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:Q9NR56}. Cytoplasm
CC       {ECO:0000250|UniProtKB:Q9NR56}. Cytoplasmic granule
CC       {ECO:0000250|UniProtKB:Q9NR56}.
CC   -!- SIMILARITY: Belongs to the muscleblind family. {ECO:0000305}.
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DR   EMBL; AJ719965; CAG31624.1; -; mRNA.
DR   RefSeq; NP_001026493.1; NM_001031322.3.
DR   AlphaFoldDB; Q5ZKW9; -.
DR   SMR; Q5ZKW9; -.
DR   STRING; 9031.ENSGALP00000016852; -.
DR   PaxDb; Q5ZKW9; -.
DR   Ensembl; ENSGALT00000076947; ENSGALP00000054130; ENSGALG00000029190.
DR   GeneID; 425033; -.
DR   KEGG; gga:425033; -.
DR   CTD; 4154; -.
DR   VEuPathDB; HostDB:geneid_425033; -.
DR   eggNOG; KOG2494; Eukaryota.
DR   GeneTree; ENSGT00950000182897; -.
DR   HOGENOM; CLU_053536_0_0_1; -.
DR   InParanoid; Q5ZKW9; -.
DR   PRO; PR:Q5ZKW9; -.
DR   Proteomes; UP000000539; Chromosome 9.
DR   Bgee; ENSGALG00000029190; Expressed in muscle tissue and 13 other tissues.
DR   ExpressionAtlas; Q5ZKW9; baseline and differential.
DR   GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR   GO; GO:0005654; C:nucleoplasm; IBA:GO_Central.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003723; F:RNA binding; IBA:GO_Central.
DR   GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR   GO; GO:0000381; P:regulation of alternative mRNA splicing, via spliceosome; IBA:GO_Central.
DR   GO; GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
DR   InterPro; IPR000571; Znf_CCCH.
DR   Pfam; PF00642; zf-CCCH; 1.
DR   SMART; SM00356; ZnF_C3H1; 4.
DR   PROSITE; PS50103; ZF_C3H1; 4.
PE   2: Evidence at transcript level;
KW   Cytoplasm; Metal-binding; mRNA processing; mRNA splicing; Nucleus;
KW   Reference proteome; Repeat; RNA-binding; Zinc; Zinc-finger.
FT   CHAIN           1..369
FT                   /note="Muscleblind-like protein 1"
FT                   /id="PRO_0000274871"
FT   ZN_FING         13..41
FT                   /note="C3H1-type 1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00723"
FT   ZN_FING         47..73
FT                   /note="C3H1-type 2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00723"
FT   ZN_FING         178..206
FT                   /note="C3H1-type 3"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00723"
FT   ZN_FING         214..240
FT                   /note="C3H1-type 4"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00723"
SQ   SEQUENCE   369 AA;  39670 MW;  0293DB3FC5D957CE CRC64;
     MAVSVTPIRD TKWLTLEVCR EFQRGTCSRP DTECKFAHPS KSCQVENGRV IACFDSLKGR
     CSRENCKYLH PPPHLKTQLE INGRNNLIQQ KNMAMLAQQM QLANAMMPGA PLQPVPMFSV
     APSLATNASA AFNPYLGPVS PGLVPAEILP TAPMLVAGNP GVPVPAAAAA AAQKLMRTDR
     LEVCREYQRG NCNRGENDCR FAHPADSAMI DTNDNTVTVC MDYIKGRCSR EKCKYFHPPA
     HLQAKIKAAQ YQVNQAAAAQ AAATAAAMGI PQAVLPPLPK RPALEKTNGA TAVFNTGIFQ
     YQQALANMQL QQHTAFLPPV PMVHGATPAT VSAATTSATS VPFAATATAN QIPIISAEHL
     TSHKYVTQM
 
 
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