ID   MBP_LEUER               Reviewed;         155 AA.
AC   Q91325;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   23-JAN-2007, sequence version 3.
DT   25-MAY-2022, entry version 60.
DE   RecName: Full=Myelin basic protein;
DE            Short=MBP;
GN   Name=MBP;
OS   Leucoraja erinacea (Little skate) (Raja erinacea).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Chondrichthyes;
OC   Elasmobranchii; Batoidea; Rajiformes; Rajidae; Leucoraja.
OX   NCBI_TaxID=7782;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   TISSUE=Brain, and Spinal cord;
RX   PubMed=7692075; DOI=10.1002/jnr.490350602;
RA   Spivack W.D., Zhong N., Salerno S., Saavedra R.A., Gould R.M.;
RT   "Molecular cloning of the myelin basic proteins in the shark, Squalus
RT   acanthias, and the ray, Raja erinacia.";
RL   J. Neurosci. Res. 35:577-584(1993).
CC   -!- FUNCTION: This protein may function to maintain proper structure of
CC       myelin.
CC   -!- SUBCELLULAR LOCATION: Myelin membrane; Peripheral membrane protein;
CC       Cytoplasmic side. Note=Cytoplasmic side of myelin.
CC   -!- SIMILARITY: Belongs to the myelin basic protein family. {ECO:0000305}.
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DR   EMBL; U44053; AAA96756.1; -; mRNA.
DR   AlphaFoldDB; Q91325; -.
DR   SMR; Q91325; -.
DR   GO; GO:0043209; C:myelin sheath; IEA:UniProtKB-SubCell.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR   GO; GO:0019911; F:structural constituent of myelin sheath; IEA:InterPro.
DR   InterPro; IPR000548; Myelin_BP.
DR   PANTHER; PTHR11429; PTHR11429; 1.
DR   Pfam; PF01669; Myelin_MBP; 1.
DR   PRINTS; PR00212; MYELINMBP.
DR   PROSITE; PS00569; MYELIN_MBP; 1.
PE   2: Evidence at transcript level;
KW   Acetylation; Cell membrane; Membrane; Phosphoprotein.
FT   INIT_MET        1
FT                   /note="Removed"
FT                   /evidence="ECO:0000250"
FT   CHAIN           2..155
FT                   /note="Myelin basic protein"
FT                   /id="PRO_0000159000"
FT   REGION          1..72
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          113..155
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOD_RES         2
FT                   /note="N-acetylalanine"
FT                   /evidence="ECO:0000250"
FT   VARIANT         31
FT                   /note="K -> Q"
FT   VARIANT         31
FT                   /note="K -> R"
SQ   SEQUENCE   155 AA;  16583 MW;  5039CDF5F66F3B81 CRC64;
     MASATTSDHA KQAGGAHSRQ RDSGLLDQLG KLFGQEGSRK VPEKGKEPAT RSVLMAPTTH
     KAHQGARRQT DDSPVVHFFK NMMSPKKAPV QQKAKSGASR AITKFIWGTD GQRAHYGAAG
     SSKSKDGFRG RKDGSGTLSS FFKMGKKGEG SPARR