MBR1_YEAS1
ID MBR1_YEAS1 Reviewed; 339 AA.
AC B3LR01;
DT 31-MAY-2011, integrated into UniProtKB/Swiss-Prot.
DT 02-SEP-2008, sequence version 1.
DT 25-MAY-2022, entry version 27.
DE RecName: Full=Mitochondrial biogenesis regulation protein 1;
GN Name=MBR1; ORFNames=SCRG_03928;
OS Saccharomyces cerevisiae (strain RM11-1a) (Baker's yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX NCBI_TaxID=285006;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=RM11-1a;
RG The Broad Institute Genome Sequencing Platform;
RA Birren B.W., Lander E.S., Galagan J.E., Nusbaum C., Devon K., Cuomo C.,
RA Jaffe D.B., Butler J., Alvarez P., Gnerre S., Grabherr M., Kleber M.,
RA Mauceli E.W., Brockman W., MacCallum I.A., Rounsley S., Young S.K.,
RA LaButti K., Pushparaj V., DeCaprio D., Crawford M., Koehrsen M., Engels R.,
RA Montgomery P., Pearson M., Howarth C., Larson L., Luoma S., White J.,
RA O'Leary S., Kodira C.D., Zeng Q., Yandava C., Alvarado L., Pratt S.,
RA Kruglyak L.;
RT "Annotation of the Saccharomyces cerevisiae RM11-1a genome.";
RL Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Participates in mitochondrial biogenesis and stress response.
CC {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Mitochondrion {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the ISF1/MBR1 family. {ECO:0000305}.
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DR EMBL; CH408051; EDV13004.1; -; Genomic_DNA.
DR AlphaFoldDB; B3LR01; -.
DR EnsemblFungi; EDV13004; EDV13004; SCRG_03928.
DR HOGENOM; CLU_778649_0_0_1; -.
DR Proteomes; UP000008335; Unassembled WGS sequence.
DR GO; GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
DR InterPro; IPR031443; Mbr1.
DR Pfam; PF17058; MBR1; 1.
PE 3: Inferred from homology;
KW Mitochondrion; Phosphoprotein; Stress response.
FT CHAIN 1..339
FT /note="Mitochondrial biogenesis regulation protein 1"
FT /id="PRO_0000408861"
FT REGION 1..20
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 93..156
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 199..224
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 258..325
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 97..118
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 134..156
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 263..321
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOD_RES 159
FT /note="Phosphothreonine"
FT /evidence="ECO:0000250|UniProtKB:P23493"
FT MOD_RES 177
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:P23493"
FT MOD_RES 224
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:P23493"
FT MOD_RES 227
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:P23493"
SQ SEQUENCE 339 AA; 37106 MW; 4F72FBC8BE549635 CRC64;
MRMEKTTDKP LSAGDMNDEY SRGPIDDIDC LNFFERAVQD PCCEACDTED ADEELRAKLS
SFNFQPDSSP CNAKCQQTLN PLCKIDEGLP AESELAPSRN GSVSEANSDT NSIASTVHDP
VDSKYGGMPS LRKAKTTSYF TSSSSNNTTM RNPLKKCNTN INGLLVNRRS SSSSRQSIPE
LFSGACTKKK NNVLLKSETP NSEFSTNSLQ HCNSRSFSLP RSRSRSSAIA IPTHLYGLEK
YVSPELDTLT ADPEESIERF SNNRPREISS CCPNDTGDTS SSLSHSNTSS SLNFPLGTNT
NQFHQPRQPV QQQQSSKPNF GAGRKKSFIE MSLASSFAG