ID   MBR1_YEAS8              Reviewed;         339 AA.
AC   C8ZC82;
DT   31-MAY-2011, integrated into UniProtKB/Swiss-Prot.
DT   03-NOV-2009, sequence version 1.
DT   25-MAY-2022, entry version 29.
DE   RecName: Full=Mitochondrial biogenesis regulation protein 1;
GN   Name=MBR1; ORFNames=EC1118_1K5_1475g;
OS   Saccharomyces cerevisiae (strain Lalvin EC1118 / Prise de mousse) (Baker's
OS   yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX   NCBI_TaxID=643680;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Lalvin EC1118 / Prise de mousse;
RX   PubMed=19805302; DOI=10.1073/pnas.0904673106;
RA   Novo M., Bigey F., Beyne E., Galeote V., Gavory F., Mallet S., Cambon B.,
RA   Legras J.-L., Wincker P., Casaregola S., Dequin S.;
RT   "Eukaryote-to-eukaryote gene transfer events revealed by the genome
RT   sequence of the wine yeast Saccharomyces cerevisiae EC1118.";
RL   Proc. Natl. Acad. Sci. U.S.A. 106:16333-16338(2009).
CC   -!- FUNCTION: Participates in mitochondrial biogenesis and stress response.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the ISF1/MBR1 family. {ECO:0000305}.
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DR   EMBL; FN393077; CAY80998.1; -; Genomic_DNA.
DR   AlphaFoldDB; C8ZC82; -.
DR   EnsemblFungi; CAY80998; CAY80998; EC1118_1K5_1475g.
DR   HOGENOM; CLU_778649_0_0_1; -.
DR   Proteomes; UP000000286; Chromosome XI, Scaffold EC1118_1K5.
DR   GO; GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
DR   InterPro; IPR031443; Mbr1.
DR   Pfam; PF17058; MBR1; 1.
PE   3: Inferred from homology;
KW   Mitochondrion; Phosphoprotein; Stress response.
FT   CHAIN           1..339
FT                   /note="Mitochondrial biogenesis regulation protein 1"
FT                   /id="PRO_0000408865"
FT   REGION          1..20
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          94..156
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          198..224
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          258..325
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        97..118
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        134..156
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        263..321
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOD_RES         159
FT                   /note="Phosphothreonine"
FT                   /evidence="ECO:0000250|UniProtKB:P23493"
FT   MOD_RES         177
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:P23493"
FT   MOD_RES         224
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:P23493"
FT   MOD_RES         227
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:P23493"
SQ   SEQUENCE   339 AA;  37007 MW;  A0D84BC451F75682 CRC64;
     MRMEKTTDKP LSAGDMNDEY SRGPIDDIDC LNFFERAVQD PCCEACDTED ADEELRAKLS
     SFNFQPDSSP CNAKCQQTLN PLCKIDEALP AESELAPSRN GSVSEANSDT NSIASTVHDP
     VDSKYGGMPS LRKAKTTSYF TSSSSNNTTM RNPLKKCNTN INGLLVNGRS SSSSRQSIPE
     LFSGACTKKK NNVLLKSETP NSEFSSNSLQ HCNSRSFSLP RSRSRSSAIA IPTHLYGLEK
     YVSPELDTLT ADPEESIERF SNNRPREISS CCPNDTGDTS SSLSHSNTSS SLNFPLGTNT
     NQFHQPRQPV QQQQSSKPNF GAGRKKSFIE MSLASSFAG