ID   MBTH_MYCTU              Reviewed;          71 AA.
AC   P9WIP5; L0T9M5; O05821;
DT   16-APR-2014, integrated into UniProtKB/Swiss-Prot.
DT   16-APR-2014, sequence version 1.
DT   03-AUG-2022, entry version 35.
DE   RecName: Full=Protein MbtH;
GN   Name=mbtH; OrderedLocusNames=Rv2377c; ORFNames=MTCY27.03;
OS   Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=83332;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 25618 / H37Rv;
RX   PubMed=9634230; DOI=10.1038/31159;
RA   Cole S.T., Brosch R., Parkhill J., Garnier T., Churcher C.M., Harris D.E.,
RA   Gordon S.V., Eiglmeier K., Gas S., Barry C.E. III, Tekaia F., Badcock K.,
RA   Basham D., Brown D., Chillingworth T., Connor R., Davies R.M., Devlin K.,
RA   Feltwell T., Gentles S., Hamlin N., Holroyd S., Hornsby T., Jagels K.,
RA   Krogh A., McLean J., Moule S., Murphy L.D., Oliver S., Osborne J.,
RA   Quail M.A., Rajandream M.A., Rogers J., Rutter S., Seeger K., Skelton S.,
RA   Squares S., Squares R., Sulston J.E., Taylor K., Whitehead S.,
RA   Barrell B.G.;
RT   "Deciphering the biology of Mycobacterium tuberculosis from the complete
RT   genome sequence.";
RL   Nature 393:537-544(1998).
RN   [2]
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RC   STRAIN=ATCC 25618 / H37Rv;
RX   PubMed=21969609; DOI=10.1074/mcp.m111.011627;
RA   Kelkar D.S., Kumar D., Kumar P., Balakrishnan L., Muthusamy B., Yadav A.K.,
RA   Shrivastava P., Marimuthu A., Anand S., Sundaram H., Kingsbury R.,
RA   Harsha H.C., Nair B., Prasad T.S., Chauhan D.S., Katoch K., Katoch V.M.,
RA   Kumar P., Chaerkady R., Ramachandran S., Dash D., Pandey A.;
RT   "Proteogenomic analysis of Mycobacterium tuberculosis by high resolution
RT   mass spectrometry.";
RL   Mol. Cell. Proteomics 10:M111.011627-M111.011627(2011).
CC   -!- FUNCTION: Could be involved in mycobactin synthesis. {ECO:0000250}.
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DR   EMBL; AL123456; CCP45165.1; -; Genomic_DNA.
DR   PIR; H70587; H70587.
DR   RefSeq; NP_216893.1; NC_000962.3.
DR   RefSeq; WP_003916994.1; NZ_NVQJ01000029.1.
DR   PDB; 2KHR; NMR; -; A=1-71.
DR   PDBsum; 2KHR; -.
DR   AlphaFoldDB; P9WIP5; -.
DR   BMRB; P9WIP5; -.
DR   SMR; P9WIP5; -.
DR   STRING; 83332.Rv2377c; -.
DR   PaxDb; P9WIP5; -.
DR   DNASU; 885968; -.
DR   GeneID; 885968; -.
DR   KEGG; mtu:Rv2377c; -.
DR   TubercuList; Rv2377c; -.
DR   eggNOG; COG3251; Bacteria.
DR   OMA; QYSLWPG; -.
DR   PhylomeDB; P9WIP5; -.
DR   BioCyc; MetaCyc:G185E-6603-MON; -.
DR   Proteomes; UP000001584; Chromosome.
DR   GO; GO:0005829; C:cytosol; IBA:GO_Central.
DR   GO; GO:0019290; P:siderophore biosynthetic process; IBA:GO_Central.
DR   DisProt; DP01509; -.
DR   InterPro; IPR005153; MbtH-like_dom.
DR   InterPro; IPR038020; MbtH-like_sf.
DR   InterPro; IPR037407; MLP_fam.
DR   PANTHER; PTHR38444; PTHR38444; 1.
DR   Pfam; PF03621; MbtH; 1.
DR   SMART; SM00923; MbtH; 1.
DR   SUPFAM; SSF160582; SSF160582; 1.
PE   1: Evidence at protein level;
KW   3D-structure; Reference proteome.
FT   CHAIN           1..71
FT                   /note="Protein MbtH"
FT                   /id="PRO_0000096276"
FT   STRAND          13..18
FT                   /evidence="ECO:0007829|PDB:2KHR"
FT   STRAND          24..27
FT                   /evidence="ECO:0007829|PDB:2KHR"
FT   STRAND          34..40
FT                   /evidence="ECO:0007829|PDB:2KHR"
FT   HELIX           45..57
FT                   /evidence="ECO:0007829|PDB:2KHR"
FT   STRAND          64..68
FT                   /evidence="ECO:0007829|PDB:2KHR"
SQ   SEQUENCE   71 AA;  8082 MW;  0F95E8FB34639B81 CRC64;
     MSTNPFDDDN GAFFVLVNDE DQHSLWPVFA DIPAGWRVVH GEASRAACLD YVEKNWTDLR
     PKSLRDAMVE D