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MC014_MCV1
ID   MC014_MCV1              Reviewed;         147 AA.
AC   Q98185; O12600; O12881;
DT   18-JUL-2018, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1997, sequence version 1.
DT   23-FEB-2022, entry version 51.
DE   RecName: Full=Protein MC014;
GN   Name=MC014;
OS   Molluscum contagiosum virus subtype 1 (MOCV) (MCVI).
OC   Viruses; Varidnaviria; Bamfordvirae; Nucleocytoviricota; Pokkesviricetes;
OC   Chitovirales; Poxviridae; Chordopoxvirinae; Molluscipoxvirus.
OX   NCBI_TaxID=10280;
OH   NCBI_TaxID=9606; Homo sapiens (Human).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=8670425; DOI=10.1126/science.273.5276.813;
RA   Senkevich T.G., Bugert J.J., Sisler J.R., Koonin E.V., Darai G., Moss B.;
RT   "Genome sequence of a human tumorigenic poxvirus: prediction of specific
RT   host response-evasion genes.";
RL   Science 273:813-816(1996).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=8938976; DOI=10.1007/bf00576975;
RA   Martin-Gallardo A., Moratilla M., Funes J.M., Agromayor M., Nunez A.,
RA   Varas A.J., Collado M., Valencia A., Lopez-Estebaranz J.L., Esteban M.;
RT   "Sequence analysis of a Molluscum contagiosum virus DNA region which
RT   includes the gene encoding protein kinase 2 and other genes with unique
RT   organization.";
RL   Virus Genes 13:19-29(1996).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=9208457; DOI=10.1023/a:1007991508159;
RA   Moratilla M., Agromayor M., Nunez A., Funes J.M., Varas A.J.,
RA   Lopez-Estebaranz J.L., Esteban M., Martin-Gallardo A.;
RT   "A random DNA sequencing, computer-based approach for the generation of a
RT   gene map of Molluscum contagiosum virus.";
RL   Virus Genes 14:73-80(1997).
RN   [4]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Lopez-Bueno A., Parras-Molto M., Lopez-Barrantes O., Belda S., Alejo A.;
RT   "Recombination events and variability among full-length genomes of co-
RT   circulating molluscum contagiosum virus subtypes 1 and 2.";
RL   J. Gen. Virol. 0:0-0(2017).
RN   [5]
RP   SUBCELLULAR LOCATION.
RX   PubMed=26041281; DOI=10.1128/jvi.00799-15;
RA   Brady G., Haas D.A., Farrell P.J., Pichlmair A., Bowie A.G.;
RT   "Poxvirus protein MC132 from molluscum contagiosum virus inhibits NF-B
RT   activation by targeting p65 for degradation.";
RL   J. Virol. 89:8406-8415(2015).
CC   -!- SUBCELLULAR LOCATION: Host nucleus {ECO:0000269|PubMed:26041281}.
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DR   EMBL; U86894; AAB57934.1; -; Genomic_DNA.
DR   EMBL; U60315; AAC55142.1; -; Genomic_DNA.
DR   EMBL; KY040275; AQY16755.1; -; Genomic_DNA.
DR   EMBL; KY040276; AQY16936.1; -; Genomic_DNA.
DR   PIR; T30616; T30616.
DR   RefSeq; NP_043965.1; NC_001731.1.
DR   GeneID; 1487035; -.
DR   KEGG; vg:1487035; -.
DR   Proteomes; UP000000869; Genome.
DR   GO; GO:0042025; C:host cell nucleus; IDA:UniProtKB.
PE   4: Predicted;
KW   Host nucleus; Reference proteome.
FT   CHAIN           1..147
FT                   /note="Protein MC014"
FT                   /id="PRO_0000444799"
SQ   SEQUENCE   147 AA;  16225 MW;  AF6750D93EBA2F1B CRC64;
     MGVSLATRKY WPARTREGGC LRWEPVPAGQ DLSCSLCDSL RVDMFLVVEP RRGLTRAGRG
     CECVRAGKRS LRGLARWPGA GAGGSAAFRA CKTRHLLQRE KCAVGRERRF CLWSGRHPKA
     PPGGRSRVRA HPGSDRVTAW LTGRRNS
 
 
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