ID   ARGP_VIBVY              Reviewed;         298 AA.
AC   Q7MHL5;
DT   19-JUL-2005, integrated into UniProtKB/Swiss-Prot.
DT   19-JUL-2005, sequence version 2.
DT   25-MAY-2022, entry version 109.
DE   RecName: Full=HTH-type transcriptional regulator ArgP {ECO:0000255|HAMAP-Rule:MF_00513};
GN   Name=argP {ECO:0000255|HAMAP-Rule:MF_00513}; Synonyms=iciA;
GN   OrderedLocusNames=VV2854;
OS   Vibrio vulnificus (strain YJ016).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC   Vibrio.
OX   NCBI_TaxID=196600;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=YJ016;
RX   PubMed=14656965; DOI=10.1101/gr.1295503;
RA   Chen C.-Y., Wu K.-M., Chang Y.-C., Chang C.-H., Tsai H.-C., Liao T.-L.,
RA   Liu Y.-M., Chen H.-J., Shen A.B.-T., Li J.-C., Su T.-L., Shao C.-P.,
RA   Lee C.-T., Hor L.-I., Tsai S.-F.;
RT   "Comparative genome analysis of Vibrio vulnificus, a marine pathogen.";
RL   Genome Res. 13:2577-2587(2003).
CC   -!- FUNCTION: Controls the transcription of genes involved in arginine and
CC       lysine metabolism. {ECO:0000255|HAMAP-Rule:MF_00513}.
CC   -!- SUBUNIT: Homodimer. {ECO:0000255|HAMAP-Rule:MF_00513}.
CC   -!- SIMILARITY: Belongs to the LysR transcriptional regulatory family.
CC       {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=BAC95618.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; BA000037; BAC95618.1; ALT_INIT; Genomic_DNA.
DR   RefSeq; WP_043877322.1; NC_005139.1.
DR   AlphaFoldDB; Q7MHL5; -.
DR   SMR; Q7MHL5; -.
DR   STRING; 672.VV93_v1c25610; -.
DR   EnsemblBacteria; BAC95618; BAC95618; BAC95618.
DR   KEGG; vvy:VV2854; -.
DR   PATRIC; fig|196600.6.peg.2842; -.
DR   eggNOG; COG0583; Bacteria.
DR   HOGENOM; CLU_063829_0_0_6; -.
DR   OMA; QQWKLDS; -.
DR   OrthoDB; 951478at2; -.
DR   Proteomes; UP000002675; Chromosome I.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:UniProtKB-UniRule.
DR   Gene3D; 1.10.10.10; -; 1.
DR   HAMAP; MF_00513; HTH_type_ArgP; 1.
DR   InterPro; IPR017685; ArgP.
DR   InterPro; IPR023490; ArgP_Gammaproteobact.
DR   InterPro; IPR005119; LysR_subst-bd.
DR   InterPro; IPR000847; Tscrpt_reg_HTH_LysR.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   Pfam; PF00126; HTH_1; 1.
DR   Pfam; PF03466; LysR_substrate; 1.
DR   PRINTS; PR00039; HTHLYSR.
DR   SUPFAM; SSF46785; SSF46785; 1.
DR   TIGRFAMs; TIGR03298; argP; 1.
DR   PROSITE; PS50931; HTH_LYSR; 1.
PE   3: Inferred from homology;
KW   DNA-binding; Reference proteome; Transcription; Transcription regulation.
FT   CHAIN           1..298
FT                   /note="HTH-type transcriptional regulator ArgP"
FT                   /id="PRO_0000105652"
FT   DOMAIN          4..60
FT                   /note="HTH lysR-type"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00513"
FT   DNA_BIND        21..40
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00513"
SQ   SEQUENCE   298 AA;  33604 MW;  E85D80C8F35AB1A3 CRC64;
     MRGLDYKWIE ALDAVVAQGG FERAAEELYI SQSAVSQRIK QLERFLAQSV LIREQPPKPT
     PVGKKLLGLY RRVRILEHEL IPELMNDDTA KPIQLALATN ADSLATWLLP ALKEVMTQRQ
     VELNLAIYGE SRSIEKLKSG EVAGAISLES QPIAGCKADY LGRMDYVCVA SPDFYQRYFA
     AGVNYQTLRK APAVSYDQYD DLHNRFLHDH FNISRDSIIN HNVGSSEAFV RLAVSGIAYC
     LIPKLQIEQE LASGVLMDIT PGFLLSYRIY WHHWQLESGV LKEISQAIVQ YAQAHLPL