MCBB_ECOLX
ID MCBB_ECOLX Reviewed; 295 AA.
AC P23184;
DT 01-NOV-1991, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1991, sequence version 1.
DT 03-AUG-2022, entry version 52.
DE RecName: Full=Microcin B17-processing protein McbB;
GN Name=mcbB;
OS Escherichia coli.
OG Plasmid IncFII pMccB17.
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=562;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=2644225; DOI=10.1128/jb.171.2.1126-1135.1989;
RA Genilloud O., Moreno F., Kolter R.;
RT "DNA sequence, products, and transcriptional pattern of the genes involved
RT in production of the DNA replication inhibitor microcin B17.";
RL J. Bacteriol. 171:1126-1135(1989).
CC -!- FUNCTION: Necessary to process the inactive microcin B17 (McbA)
CC precursor into the active peptide.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000305}.
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DR EMBL; M24253; AAA72742.1; -; Genomic_DNA.
DR PIR; B32058; B32058.
DR PDB; 6GOS; X-ray; 2.10 A; 1/2=1-295.
DR PDB; 6GRG; X-ray; 2.35 A; 1/2=1-295.
DR PDB; 6GRH; X-ray; 1.85 A; 1/2=1-295.
DR PDB; 6GRI; X-ray; 2.70 A; 1/2=1-295.
DR PDBsum; 6GOS; -.
DR PDBsum; 6GRG; -.
DR PDBsum; 6GRH; -.
DR PDBsum; 6GRI; -.
DR AlphaFoldDB; P23184; -.
DR SMR; P23184; -.
DR BioCyc; MetaCyc:MON-21086; -.
DR BRENDA; 1.3.3.16; 2026.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0017000; P:antibiotic biosynthetic process; IEA:UniProtKB-KW.
DR InterPro; IPR030956; McbB.
DR TIGRFAMs; TIGR04424; metallo_McbB; 1.
PE 1: Evidence at protein level;
KW 3D-structure; Antibiotic biosynthesis; Cytoplasm; Plasmid.
FT CHAIN 1..295
FT /note="Microcin B17-processing protein McbB"
FT /id="PRO_0000068571"
FT STRAND 13..15
FT /evidence="ECO:0007829|PDB:6GRH"
FT STRAND 17..23
FT /evidence="ECO:0007829|PDB:6GRH"
FT STRAND 26..38
FT /evidence="ECO:0007829|PDB:6GRH"
FT HELIX 41..52
FT /evidence="ECO:0007829|PDB:6GRH"
FT STRAND 55..57
FT /evidence="ECO:0007829|PDB:6GRH"
FT HELIX 59..68
FT /evidence="ECO:0007829|PDB:6GRH"
FT HELIX 73..82
FT /evidence="ECO:0007829|PDB:6GRH"
FT STRAND 85..88
FT /evidence="ECO:0007829|PDB:6GRH"
FT STRAND 96..103
FT /evidence="ECO:0007829|PDB:6GRH"
FT HELIX 105..108
FT /evidence="ECO:0007829|PDB:6GRH"
FT HELIX 111..115
FT /evidence="ECO:0007829|PDB:6GRH"
FT HELIX 116..118
FT /evidence="ECO:0007829|PDB:6GRH"
FT STRAND 122..127
FT /evidence="ECO:0007829|PDB:6GRH"
FT STRAND 139..144
FT /evidence="ECO:0007829|PDB:6GRH"
FT HELIX 150..160
FT /evidence="ECO:0007829|PDB:6GRH"
FT STRAND 167..175
FT /evidence="ECO:0007829|PDB:6GRH"
FT STRAND 177..180
FT /evidence="ECO:0007829|PDB:6GRH"
FT TURN 186..189
FT /evidence="ECO:0007829|PDB:6GRH"
FT HELIX 193..204
FT /evidence="ECO:0007829|PDB:6GRH"
FT STRAND 205..208
FT /evidence="ECO:0007829|PDB:6GRH"
FT HELIX 215..220
FT /evidence="ECO:0007829|PDB:6GRH"
FT HELIX 236..254
FT /evidence="ECO:0007829|PDB:6GRH"
FT TURN 263..267
FT /evidence="ECO:0007829|PDB:6GRH"
FT STRAND 268..273
FT /evidence="ECO:0007829|PDB:6GRH"
FT TURN 274..276
FT /evidence="ECO:0007829|PDB:6GRH"
FT STRAND 279..282
FT /evidence="ECO:0007829|PDB:6GRH"
FT HELIX 292..294
FT /evidence="ECO:0007829|PDB:6GRH"
SQ SEQUENCE 295 AA; 33985 MW; B9ACBA72706423AF CRC64;
MVLPDIKKGK DMINILPFEI ISRNTKTLLI TYISSVDITH EGMKKVLESL RSKQGIISEY
LLDKLLDESL IDKDKGKEFL ITTGVINKTK TSPLWVNSVI ISDVPHLFSN AREQWKCDGV
FVSHIIDIKD NNINVSDSTL IWLHLENYHS DIVKRIYSKF ESNPGVAFIQ SYYLKESFRI
DGVYSPDLGT PCHFCHIERW LSREEKSFRR NEMSWANLLQ LLKKYQMTLP ALALGESERG
FSYHLIKRRL QELTGTSLVK SHVDNFMSSV SADLITCILC KEPVIHWQAC SCLER
