MCBG_ECOLX
ID MCBG_ECOLX Reviewed; 187 AA.
AC P05530;
DT 01-NOV-1988, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1988, sequence version 1.
DT 25-MAY-2022, entry version 71.
DE RecName: Full=Protein McbG {ECO:0000303|PubMed:3049078};
DE AltName: Full=Pentapeptide repeat protein McbG {ECO:0000305};
GN Name=mcbG;
OS Escherichia coli.
OG Plasmid IncFII pMccB17.
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=562;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA], AND ANTIBIOTIC RESISTANCE.
RC PLASMID=IncFII pMccB17;
RX PubMed=3049078; DOI=10.1002/j.1460-2075.1988.tb03018.x;
RA Garrido M.D.C., Herrero M., Kolter R., Moreno F.;
RT "The export of the DNA replication inhibitor microcin B17 provides immunity
RT for the host cell.";
RL EMBO J. 7:1853-1862(1988).
CC -!- FUNCTION: Together with proteins McbE and McbF this protein causes
CC immunity to the peptide antibiotic microcin B17 (MccB17), which
CC inhibits DNA replication in Enterobacteriaceae by induction of the SOS
CC repair system. McbG alone can provide some protection.
CC {ECO:0000269|PubMed:3049078}.
CC -!- SIMILARITY: Belongs to the pentapeptide repeat protein family.
CC {ECO:0000305}.
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DR EMBL; X07875; CAA30724.1; -; Genomic_DNA.
DR PIR; S00837; S00837.
DR RefSeq; WP_000351266.1; NZ_WSWV01000078.1.
DR AlphaFoldDB; P05530; -.
DR SMR; P05530; -.
DR GO; GO:0046677; P:response to antibiotic; IEA:UniProtKB-KW.
DR InterPro; IPR001646; 5peptide_repeat.
DR Pfam; PF13599; Pentapeptide_4; 1.
PE 3: Inferred from homology;
KW Antibiotic resistance; Plasmid.
FT CHAIN 1..187
FT /note="Protein McbG"
FT /id="PRO_0000068575"
SQ SEQUENCE 187 AA; 21848 MW; BB350883C4491AC0 CRC64;
MDIIEKRITK RHLSESELSG VNYYNCIFER IQLDNFNFRD CEFEKCRFVN CSIKNLKLNF
FKLIDCEFKD CLLQGVNAAD IMFPCTFSLV NCDLRFVDFI SLRLQKSIFL SCRFRDCLFE
ETDLRKSDFT GSEFNNTEFR HSDLSHCDFS MTEGLDINPE INRILSIKIP QEAGLKILKR
MGVVVGG